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Text
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URL Address
<a href="http://doi.org/10.1542/peds.2006-1609" target="_blank" rel="noreferrer">http://doi.org/10.1542/peds.2006-1609</a>
<a href="http://pediatrics.aappublications.org/content/119/2/e519.abstract" target="_blank" rel="noreferrer">http://pediatrics.aappublications.org/content/119/2/e519.abstract</a>
Dublin Core
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Title
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Gabapentin Successfully Manages Chronic Unexplained Irritability in Children With Severe Neurologic Impairment
Publisher
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Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2007
Subject
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Child; Female; Humans; Male; Adult; Severity of Illness Index; adolescent; Preschool; infant; Chronic disease; retrospective studies; Nervous System Diseases/complications; Analgesics/therapeutic use; Amines/therapeutic use; Cyclohexanecarboxylic Acids/therapeutic use; gamma-Aminobutyric Acid/therapeutic use; Irritable Mood/drug effects; Remission Induction
Creator
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Hauer JM; Wical BS; Charnas L
Description
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Neurologically impaired children have an increased frequency of recurrent pain and irritability that persist in some despite comprehensive evaluation and management of possible pain sources. We hypothesized that visceral hyperalgesia was a source of chronic unexplained irritability and report the outcome of gabapentin treatment in 9 severely neurologically impaired children. Caregivers reported marked improvement after treatment ranging from 3 months to 3 years. Nystagmus in 1 child was the only noted adverse effect. Visceral hyperalgesia may be a source of unexplained irritability in the neurologically impaired child. Symptoms may improve with gabapentin treatment.
2007-02
Identifier
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<a href="http://doi.org/10.1542/peds.2006-1609" target="_blank" rel="noreferrer">10.1542/peds.2006-1609</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2007
Adolescent
Adult
Amines/therapeutic use
Analgesics/therapeutic use
Backlog
Charnas L
Child
Chronic Disease
Cyclohexanecarboxylic Acids/therapeutic use
Female
gamma-Aminobutyric Acid/therapeutic use
Hauer JM
Humans
Infant
Irritable Mood/drug effects
Journal Article
Male
Nervous System Diseases/complications
Pediatrics
Preschool
Remission Induction
Retrospective Studies
Severity Of Illness Index
Wical BS