1
40
3
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1097/00002508-200503000-00012" target="_blank" rel="noreferrer">http://doi.org/10.1097/00002508-200503000-00012</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Analgesic effects of topical methadone: a report of four cases
Publisher
An entity responsible for making the resource available
The Clinical Journal Of Pain
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
Subject
The topic of the resource
Female; Humans; Male; Analgesics; Aged; Middle Aged; Treatment Outcome; Bandages; 80 and over; Administration; Pain/drug therapy/etiology; Palliative Care/methods; Opioid/administration & dosage; Wounds; Methadone/administration & dosage; Penetrating/complications; Topical
Creator
An entity primarily responsible for making the resource
Gallagher RE; Arndt DR; Hunt KL
Description
An account of the resource
Topical morphine has been used on open wounds for pain management, but has a variable duration of action not suitable for palliative dressing changes. The objective of this study is to find an opioid and delivery method that would provide long-lasting pain relief between dressing changes. Methadone powder (100 mg) was mixed in Stomahesive powder (10 g) and sprinkled on the open wound once daily at the time of dressing change. Four cases are presented with varying results using the methadone/Stomahesive mixture. Exudative wounds with exposed tissue work best, whereas dry wounds with eschar show less response. Topical methadone powder can be effective for pain relief in open, exudative wounds with little eschar. Further research questions are raised.
2005
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/00002508-200503000-00012" target="_blank" rel="noreferrer">10.1097/00002508-200503000-00012</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2005
80 And Over
Administration
Aged
Analgesics
Arndt DR
Backlog
Bandages
Female
Gallagher RE
Humans
Hunt KL
Journal Article
Male
Methadone/administration & Dosage
Middle Aged
Opioid/administration & dosage
Pain/drug therapy/etiology
Palliative Care/methods
Penetrating/complications
The Clinical Journal Of Pain
Topical
Treatment Outcome
Wounds
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16495423" target="_blank" rel="noreferrer">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16495423</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The decision to use topical anesthetic for intravenous insertion in the pediatric emergency department
Publisher
An entity responsible for making the resource available
Academic Emergency Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2006
Subject
The topic of the resource
Child; Female; Humans; Male; Pennsylvania; Clinical Competence; Sensitivity and Specificity; Clinical Protocols; Anesthetics; Preschool; PedPal Lit; Comparative Study; Administration; Infusions; Hospital; Nursing Assessment/methods; Topical; Emergency Service; Pain/drug therapy/etiology; Emergency Nursing/methods/standards; Intravenous/adverse effects/nursing; Local/administration & dosage; Pediatric Nursing/methods; Triage/standards
Creator
An entity primarily responsible for making the resource
Fein JA; Gorelick MH
Description
An account of the resource
OBJECTIVES: Topical anesthetic creams to reduce the pain of intravenous (IV) placement may be more effectively used in the emergency setting if they are applied by nurses in the triage area of the emergency department or soon after the patient is placed into a room. This strategy requires accurate prediction of which patients will require IV placement. The objective of this study was to compare triage nurse judgment regarding IV placement in pediatric patients with a triage prediction rule using chief complaint, referral status, and high-risk medical history. A secondary objective was to evaluate whether the presence of the anesthetic cream placed in triage influenced the subsequent decision to place an IV and thus invalidate the prediction strategy. METHODS: Triage nurses were randomly assigned to a prediction score group (PRD), classifying patients as "IV likely" if the prediction score was > or =2, or an "own judgment" (RN JDGMT) group, classifying any patient that he or she considered to have a > or =50% risk of receiving an IV. The rate of actual IV placement in the emergency department treatment rooms was compared between the triage prediction strategies. To assess the influence of the presence of lidocaine 2.5% and prilocaine 2.5% (EMLA cream) on the judgment to place an IV, only 75% of the "IV likely" patients had EMLA applied in triage; the IV placement rate was compared between "IV likely" patients who did or did not have EMLA applied. RESULTS: The authors enrolled 3,790 of 5,025 (75.4%) of eligible patients. The RN JDGMT group predicted 165 of 250 (66%; 95% confidence interval = 59% to 72%) of IVs placed, compared with 127 of 305 (41%; 95% CI = 36% to 47%) in the PRD group (p < 0.0001). Positive predictive values were 59% and 53% for the RN JDGMNT and PRD groups, respectively. There was no difference in IV placement rates in the "IV likely" patients who did and did not have EMLA applied. CONCLUSIONS: Triage nurse judgment to predict eventual IV placement had greater sensitivity and similar predictive value compared with a prediction model based on medical history and chief complaint. The triage placement of topical anesthetic in pediatric patients did not change the eventual rate of IV placement.
2006
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2006
Academic Emergency Medicine
Administration
Anesthetics
Backlog
Child
Clinical Competence
Clinical Protocols
Comparative Study
Emergency Nursing/methods/standards
Emergency Service
Fein JA
Female
Gorelick MH
Hospital
Humans
Infusions
Intravenous/adverse effects/nursing
Journal Article
Local/administration & dosage
Male
Nursing Assessment/methods
Pain/drug therapy/etiology
Pediatric Nursing/methods
PedPal Lit
Pennsylvania
Preschool
Sensitivity and Specificity
Topical
Triage/standards
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1124/pr.55.1.1" target="_blank" rel="noreferrer">http://doi.org/10.1124/pr.55.1.1</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Topical and peripherally acting analgesics
Publisher
An entity responsible for making the resource available
Pharmacological Reviews
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
Subject
The topic of the resource
Humans; Animals; Non-U.S. Gov't; Research Support; Administration; Neurons; Peripheral Nervous System/drug effects; Topical; Afferent/drug effects/metabolism/physiology; Analgesics/administration & dosage/pharmacology/therapeutic use; Nociceptors/metabolism/physiology; Pain/drug therapy/metabolism/physiopathology; Signal Transduction/drug effects/physiology
Creator
An entity primarily responsible for making the resource
Sawynok J
Description
An account of the resource
Acute nociceptive, inflammatory, and neuropathic pain all depend to some degree on the peripheral activation of primary sensory afferent neurons. The localized peripheral administration of drugs, such as by topical application, can potentially optimize drug concentrations at the site of origin of the pain, while leading to lower systemic levels and fewer adverse systemic effects, fewer drug interactions, and no need to titrate doses into a therapeutic range compared with systemic administration. Primary sensory afferent neurons can be activated by a range of inflammatory mediators such as prostanoids, bradykinin, ATP, histamine, and serotonin, and inhibiting their actions represents a strategy for the development of analgesics. Peripheral nerve endings also express a variety of inhibitory neuroreceptors such as opioid, alpha-adrenergic, cholinergic, adenosine and cannabinoid receptors, and agonists for these receptors also represent viable targets for drug development. At present, topical and other forms of peripheral administration of nonsteroidal anti-inflammatory drugs, opioids, capsaicin, local anesthetics, and alpha-adrenoceptor agonists are being used in a variety of clinical states. There also are some clinical data on the use of topical antidepressants and glutamate receptor antagonists. There are preclinical data supporting the potential for development of local formulations of adenosine agonists, cannabinoid agonists, cholinergic ligands, cytokine antagonists, bradykinin antagonists, ATP antagonists, biogenic amine antagonists, neuropeptide antagonists, and agents that alter the availability of nerve growth factor. Given that activation of sensory neurons involves multiple mediators, combinations of agents targeting different mechanisms may be particularly useful. Topical analgesics represent a promising area for future drug development.
2003
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1124/pr.55.1.1" target="_blank" rel="noreferrer">10.1124/pr.55.1.1</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2003
Administration
Afferent/drug effects/metabolism/physiology
Analgesics/administration & dosage/pharmacology/therapeutic use
Animals
Backlog
Humans
Journal Article
Neurons
Nociceptors/metabolism/physiology
Non-U.S. Gov't
Pain/drug therapy/metabolism/physiopathology
Peripheral Nervous System/drug effects
Pharmacological Reviews
Research Support
Sawynok J
Signal Transduction/drug effects/physiology
Topical