1
40
21
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.3171/2011.8.PEDS11153" target="_blank" rel="noreferrer noopener">http://doi.org/10.3171/2011.8.PEDS11153</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Deep brain stimulation in children: experience and technical pearls
Publisher
An entity responsible for making the resource available
Journal of Neurosurgery - Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
Subject
The topic of the resource
Adolescent; Adult; Age; Factors Brain/pa [Pathology]; Brain/ra [Radiography]; Child; Preschool; Deep Brain Stimulation/ae [Adverse Effects]; Deep Brain Stimulation/mt [Methods]; Dystonia/pp [Physiopathology]; Dystonia/th [Therapy]; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Movement; Retrospective Studies; Tomography; X-Ray Computed Treatment Outcome; tone and motor problems; Glutaric acidemia type I; Lesch-Nyhan syndrome; deep brain stimulation; secondary dystonia
Creator
An entity primarily responsible for making the resource
Air E L; Ostrem J L; Sanger T D; Starr P A
Description
An account of the resource
OBJECT: Deep brain stimulation (DBS) is an established technique for the treatment of several movement disorders in adults. However, the technical approach, complications, and results of DBS in children have not been well documented. METHODS: A database of DBS implantations performed at a single institution, prospectively established in 1998, was reviewed for patients who received DBS prior to the age of 18. Diagnoses, surgical technique, and complications were noted. Outcomes were assessed using standard rating scales of neurological function. RESULTS: Of 815 patients undergoing DBS implantation over a 12-year period, 31 were children (mean age at surgery 13.2 years old, range 4-17 years old). Diagnoses included the following: DYT1 primary dystonia (autosomal dominant, Tor1ADELTAGAG mutation, 10 cases), non-DYT1 primary dystonia (3 cases), secondary dystonia (11 cases), neurodegeneration with brain iron accumulation (NBIA, 3 cases), levodopa-responsive parkinsonism (2 cases), Lesch-Nyhan disease (1 case), and glutaric aciduria Type 1 (1 case). Six children ages 15-17 years old underwent awake microelectrode-guided surgery. For 25 children operated under general anesthesia, the surgical technique evolved from microelectrode-guided surgery to image-guided surgeries using real-time intraoperative MR imaging or CT for lead location confirmation. Complications included 5 hardware infections, all in children younger than 10 years old. At 1 year after implantation, patients with DYT1 dystonia had a mean improvement in the Burke-Fahn-Marsden Dystonia Rating Scale movement subscore of 75%, while those with secondary dystonia had only small improvements. Outcomes in the 3 children with NBIA were disappointing. CONCLUSIONS: Results of DBS in children with primary and secondary dystonias were similar to those in adults, with excellent results for DYT1 dystonia in children without fixed orthopedic deformity and much more modest results in secondary dystonia. In contrast to reported experience in adults with NBIA, these results in children with NBIA were poor. Infection risk was highest in the youngest patients.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3171/2011.8.PEDS11153" target="_blank" rel="noreferrer noopener">10.3171/2011.8.PEDS11153</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2011
Adolescent
Adult
Age
Air E L
Brain/ra [Radiography]
Child
deep brain stimulation
Deep Brain Stimulation/ae [Adverse Effects]
Deep Brain Stimulation/mt [Methods]
Dystonia/pp [Physiopathology]
Dystonia/th [Therapy]
Factors Brain/pa [Pathology]
Female
Follow-up Studies
Glutaric acidemia type I
Humans
Journal of Neurosurgery - Pediatrics
Lesch-Nyhan syndrome
Magnetic Resonance Imaging
Male
Movement
Ostrem J L
Preschool
Retrospective Studies
Sanger T D
secondary dystonia
Starr P A
Tomography
tone and motor problems
X-Ray Computed Treatment Outcome
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1155/2013/327903" target="_blank" rel="noreferrer">http://doi.org/10.1155/2013/327903</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Postmortem computed tomography imaging in the investigation of nontraumatic death in infants and children
Publisher
An entity responsible for making the resource available
Biomed Research International
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
Subject
The topic of the resource
Child; Female; Humans; infant; Male; Death; Autopsy; Preschool; Newborn; Tomography; X-Ray Computed
Creator
An entity primarily responsible for making the resource
Noda Y; Yoshimura K; Tsuji Shoji; Ohashi A; Kawasaki H; Kaneko K; Ikeda S; Kurokawa H; Tanigawa N
Description
An account of the resource
OBJECTIVE: To determine the accuracy of postmortem computed tomography (PMCT) for the assessment of causes in nontraumatic deaths in children. STUDY DESIGN: We enrolled cases of nontraumatic deaths of infants and children who underwent PMCT at a single center. The presumed cause of death determined by PMCT was prospectively compared with the clinical and pathological diagnoses of deaths. RESULTS: Thirty-eight cases were enrolled for analysis. Among them, seven cases also underwent conventional medical autopsy. PMCT revealed an identifiable cause of death in accordance with the clinical diagnosis of death in 16 cases of the 38 cases (the concordance rate was 42%) and in accordance with the autopsy cause of death in four of the seven autopsy cases (the concordance rate was 57%). Among eight cases with unknown cause of death by clinical diagnosis, four cases (50%) were identified with cardiac tamponade as a cause of death (one case) and intracranial hemorrhage suggesting abuse (3 cases). CONCLUSIONS: PMCT seems to be a promising technique that might serve as a substitute for conventional medical autopsy and give us the complementary information to clinical diagnoses particularly in cases of child abuse. Larger multicenter trials are worthwhile to validate the general feasibility of PMCT.
2013
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1155/2013/327903" target="_blank" rel="noreferrer">10.1155/2013/327903</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2013
Autopsy
Backlog
Biomed Research International
Child
Death
Female
Humans
Ikeda S
Infant
Journal Article
Kaneko K
Kawasaki H
Kurokawa H
Male
Newborn
Noda Y
Ohashi A
Preschool
Tanigawa N
Tomography
Tsuji Shoji
X-Ray Computed
Yoshimura K
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.3171/2013.4.PEDS12474" target="_blank" rel="noreferrer">http://doi.org/10.3171/2013.4.PEDS12474</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Percutaneous CT-guided cordotomy for the treatment of pediatric cancer pain
Publisher
An entity responsible for making the resource available
Journal Of Neurosurgery. Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
Subject
The topic of the resource
Child; Humans; Male; Palliative Care; Pain; hospice care; Treatment Outcome; Palliative Care; Tomography; X-Ray Computed; Intractable; Cordotomy; Groin; Lower Extremity; Medulloblastoma
Creator
An entity primarily responsible for making the resource
Reddy GD; Okhuysen-Cawley R; Harsh V; Viswanathan A
Description
An account of the resource
Percutaneous cordotomy using CT guidance has been shown to be a safe and effective means of reducing pain in adults with cancer in 2 large case series. Its effectiveness in pediatric patients, however, has not been reported. Here, the authors present a case of CT-guided percutaneous cordotomy being used effectively for the treatment of unilateral limb pain in a 9-year-old boy suffering from metastatic medulloblastoma. The efficacy and minimally invasive nature of this procedure support its use in selected pediatric cases.
2013-07
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3171/2013.4.PEDS12474" target="_blank" rel="noreferrer">10.3171/2013.4.PEDS12474</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2013
Backlog
Child
Cordotomy
Groin
Harsh V
Hospice Care
Humans
Intractable
Journal Article
Journal Of Neurosurgery. Pediatrics
Lower Extremity
Male
Medulloblastoma
Okhuysen-Cawley R
Pain
Palliative Care
Reddy GD
Tomography
Treatment Outcome
Viswanathan A
X-Ray Computed
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1097/BPO.0b013e3181558bc1" target="_blank" rel="noreferrer">http://doi.org/10.1097/BPO.0b013e3181558bc1</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Diagnostic evaluation using whole-body technetium bone scan in children with cerebral palsy and pain.
Publisher
An entity responsible for making the resource available
Journal Of Pediatric Orthopedics
Date
A point or period of time associated with an event in the lifecycle of the resource
2008
Subject
The topic of the resource
Child; Female; Humans; Male; Pain Measurement; Adult; Severity of Illness Index; Reproducibility of Results; adolescent; Preschool; retrospective studies; Emission-Computed; Tomography; Diagnosis; Differential; Bone and Bones/radionuclide imaging; Cerebral Palsy/complications/radionuclide imaging; Pain/etiology/radionuclide imaging; Single-Photon/methods; Technetium/diagnostic use; Whole Body Imaging/methods
Creator
An entity primarily responsible for making the resource
Bajelidze G; Belthur MV; Littleton AG; Dabney Kirk W; Miller F
Description
An account of the resource
BACKGROUND: Pain in noncommunicative children can be difficult to localize and diagnose. The purpose of this study is to report our experience using a 3-phase whole-body technetium bone scan as a screening tool in identifying the source of persistent pain in children with profound disabilities who cannot communicate. METHODS: We reviewed the medical and imaging records of 45 patients who met the inclusion criteria of the study, which included a diagnosis of spastic quadriplegic cerebral palsy with severe motor and cognitive impairment, persistent pain of more than 1 week in duration with no recognizable source, and a 3-phase whole-body bone scan as part of the pain workup. RESULTS: The study group included 26 females and 19 males with an average age at presentation of 13.5 years (range, 3-20 years). A positive bone scan was seen in 24 patients (53%). The diagnosis and the source of pain were identified in all 24 patients with a positive bone scan, with the bone scan being instrumental in establishing a diagnosis or localization in 22 patients. An orthopaedic diagnosis was not established in the 21 other patients with a negative bone scan. Based on the bone scan results, additional imaging was obtained at the anatomical location indicated. The bone scan was used to establish a diagnosis of fracture in 10 of 24 patients. Other diagnoses included 3 patients with painful internal hardware, 2 with sinusitis, 2 with infections, and 1 with an obstructed kidney. CONCLUSIONS: Whole-body bone scan is a viable imaging option to identify the source of persistent pain in children who are noncommunicative. The bone scan can assist in localizing the source of pain and direct the location for further imaging as needed.
2008-02
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/BPO.0b013e3181558bc1" target="_blank" rel="noreferrer">10.1097/BPO.0b013e3181558bc1</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2008
Adolescent
Adult
Backlog
Bajelidze G
Belthur MV
Bone and Bones/radionuclide imaging
Cerebral Palsy/complications/radionuclide imaging
Child
Dabney Kirk W
Diagnosis
Differential
Emission-Computed
Female
Humans
Journal Article
Journal Of Pediatric Orthopedics
Littleton AG
Male
Miller F
Pain Measurement
Pain/etiology/radionuclide imaging
Preschool
Reproducibility of Results
Retrospective Studies
Severity Of Illness Index
Single-Photon/methods
Technetium/diagnostic use
Tomography
Whole Body Imaging/methods
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1227/01.NEU.0000327885.15132.CA" target="_blank" rel="noreferrer">http://doi.org/10.1227/01.NEU.0000327885.15132.CA</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Direct measurement of intracranial pressure at high altitude and correlation of ventricular size with acute mountain sickness: Brian Cummins' results from the 1985 Kishtwar expedition
Publisher
An entity responsible for making the resource available
Neurosurgery
Date
A point or period of time associated with an event in the lifecycle of the resource
2008
Subject
The topic of the resource
Humans; Male; Young Adult; Adult; Middle Aged; Severity of Illness Index; Intracranial Pressure; Acute Disease; adolescent; Tomography; X-Ray Computed; India; Altitude Sickness/diagnosis/etiology/physiopathology; Brain/complications/physiopathology; Cerebral Ventricles/physiopathology; Expeditions; Experimental; Headache/etiology; Hypoxia; Implants; Intracranial Hypertension/diagnosis/etiology; Physical Exertion; Telemetry/instrumentation
Creator
An entity primarily responsible for making the resource
Wilson MH; Milledge J
Description
An account of the resource
OBJECTIVE AND IMPORTANCE: The "tight-fit" hypothesis and subsequent current understanding of acute mountain sickness (AMS) is that individuals with less compliant cerebrospinal fluid systems (smaller ventricles and cerebrospinal fluid spaces) have a greater increase in intracranial pressure (ICP) for a given increase in brain volume as a result of hypoxic cerebral edema. There has only been 1 study of direct (telemetric) ICP measurement at high altitude. This was performed in 1985 on 3 subjects by Brian Cummins up to a maximum height of 16,500 ft (5030 m). The group also investigated the "tight-fit" hypothesis by correlating computed tomographic scans that measured ventricular size (read blindly) with headache score and AMS symptomatology in 10 subjects. Unfortunately, the data were thought to have been destroyed by fire, and, hence, the findings were not published. The data have now been rediscovered, and this article reviews the methodology and findings of this unique piece of work. RESULTS: The ICP monitoring study demonstrated that ICP remained normal at rest at all altitudes; however, in the single subject with AMS, there was a dramatic increase in ICP even on minimal exertion. The computed tomographic scan analysis of brain compliance demonstrated an inverse correlation between ventricular size and headache score. CONCLUSION: This unique research, which is unlikely to ever be repeated, is the only report of direct ICP measurement at high altitude. This and the computed tomographic study provide the first objective evidence supporting the "tight-fit" hypothesis of AMS.
2008
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1227/01.NEU.0000327885.15132.CA" target="_blank" rel="noreferrer">10.1227/01.NEU.0000327885.15132.CA</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2008
Acute Disease
Adolescent
Adult
Altitude Sickness/diagnosis/etiology/physiopathology
Backlog
Brain/complications/physiopathology
Cerebral Ventricles/physiopathology
Expeditions
Experimental
Headache/etiology
Humans
Hypoxia
Implants
India
Intracranial Hypertension/diagnosis/etiology
Intracranial Pressure
Journal Article
Male
Middle Aged
Milledge J
Neurosurgery
Physical Exertion
Severity Of Illness Index
Telemetry/instrumentation
Tomography
Wilson MH
X-Ray Computed
Young Adult
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1542/peds.2008-1159" target="_blank" rel="noreferrer">http://doi.org/10.1542/peds.2008-1159</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Neuroimaging-use trends in nonacute pediatric headache before and after clinical practice parameters
Publisher
An entity responsible for making the resource available
Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2008
Subject
The topic of the resource
Child; Cross-Sectional Studies; Female; Humans; Male; adolescent; Preschool; Physician's Practice Patterns/statistics & numerical data; retrospective studies; Tomography; Headache/diagnosis; Magnetic Resonance Imaging/utilization; X-Ray Computed/utilization
Creator
An entity primarily responsible for making the resource
Graf WD; Kayyali HR; Alexander JJ; Simon SD; Morriss MC
Description
An account of the resource
OBJECTIVES: The objective of this study was to determine trends in diagnostic neuroimaging-use rates in nonacute pediatric headache before and after publication of clinical practice guidelines. METHODS: Retrospective, cross-sectional analysis was conducted of neuroimaging rates for 725 children and adolescents who were aged 3 to 18 years with nonacute headache and normal neurologic examination and were evaluated in a single pediatric neurology clinic during study years 1992, 1996, 2000, and 2004. Following recommendations of current practice parameters, patients with conditions that justify consideration for neuroimaging (eg, progressive headache, abnormal neurologic examination) were excluded from this analysis. We recorded the origin of any neuroimaging request at the time of the clinic visit and any abnormal neuroimaging findings that led to major clinical consequences. RESULTS: Overall, the mean rate of neuroimaging for patients with nonacute headache was 45%. Use rates remained steady during the 13-year study period (range: 41%-47%). The majority of neuroimaging studies were ordered originally by primary care providers. The proportion of neuroimaging studies that were ordered by primary care providers increased significantly from 1992 to 2004. CONCLUSIONS: In the evaluation of patients who had nonacute pediatric headache and were referred to a child neurology clinic, neuroimaging-use rates remained stable during the past decade. An increasing proportion of neuroimaging studies are ordered by primary care providers. The influence of evidence-based medicine on medical decision-making may be partly responsible for curbing increases in neuroimaging overuse. The perceived value of neuroimaging by physicians and consumers deserves ongoing study.
2008
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1542/peds.2008-1159" target="_blank" rel="noreferrer">10.1542/peds.2008-1159</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2008
Adolescent
Alexander JJ
Backlog
Child
Cross-sectional Studies
Female
Graf WD
Headache/diagnosis
Humans
Journal Article
Kayyali HR
Magnetic Resonance Imaging/utilization
Male
Morriss MC
Pediatrics
Physician's Practice Patterns/statistics & numerical data
Preschool
Retrospective Studies
Simon SD
Tomography
X-Ray Computed/utilization
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/j.jpeds.2004.11.031" target="_blank" rel="noreferrer">http://doi.org/10.1016/j.jpeds.2004.11.031</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Gastric sensory and motor dysfunction in adolescents with functional dyspepsia
Publisher
An entity responsible for making the resource available
The Journal Of Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
Subject
The topic of the resource
Female; Humans; Male; adolescent; Non-U.S. Gov't; P.H.S.; Research Support; U.S. Gov't; Emission-Computed; Tomography; Receptors; Breath Tests; Dyspepsia/physiopathology; Gastric Emptying; Sensory/physiopathology; Single-Photon; Stomach/physiopathology
Creator
An entity primarily responsible for making the resource
Chitkara DK; Camilleri M; Zinsmeister AR; Burton D; El-Youssef M; Freese D; Walker L; Stephens D
Description
An account of the resource
OBJECTIVES: Validated, noninvasive studies were used to compare sensation and motor function of the upper gastrointestinal tract in adolescents with functional dyspepsia (FD) and in control subjects. STUDY DESIGN: Fifteen adolescents with FD and 15 healthy participants underwent standardized symptom assessment, a satiation nutrient drink test, and 13 C-Spirulina platensis breath test for gastric emptying of solids. Adolescents with FD also underwent measurements of fasting and postprandial gastric volume by means of single-photon emission computed tomography, and their results were compared with those from 15 healthy volunteers (age, 18 to 25 years). RESULTS: Compared with control subjects, adolescents with FD had significantly higher postprandial symptoms 30 minutes after reaching maximum satiation with the nutrient drink test and significant delay in the T 1/2 for gastric emptying of solids. Compared with healthy 18- to 25-year-old adults, adolescents had a diminished postprandial gastric volume response. By means of single-photon emission computed tomography, frequent baseline dyspeptic symptoms were associated with prolonged T 1/2 for gastric emptying and higher postprandial aggregate symptom score. A baseline increased severity of dyspepsia symptoms was associated with prolonged T 1/2 for gastric emptying. CONCLUSIONS: Adolescents with FD demonstrate increased postprandial symptoms after challenge, delayed gastric emptying, and a reduced gastric volume response to feeding.
2005
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jpeds.2004.11.031" target="_blank" rel="noreferrer">10.1016/j.jpeds.2004.11.031</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2005
Adolescent
Backlog
Breath Tests
Burton D
Camilleri M
Chitkara DK
Dyspepsia/physiopathology
El-Youssef M
Emission-Computed
Female
Freese D
Gastric Emptying
Humans
Journal Article
Male
Non-U.S. Gov't
P.H.S.
Receptors
Research Support
Sensory/physiopathology
Single-Photon
Stephens D
Stomach/physiopathology
The Journal Of Pediatrics
Tomography
U.S. Gov't
Walker L
Zinsmeister AR
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1001/archpsyc.61.1.34" target="_blank" rel="noreferrer">http://doi.org/10.1001/archpsyc.61.1.34</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy
Publisher
An entity responsible for making the resource available
Archives Of General Psychiatry
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
Subject
The topic of the resource
Female; Humans; Male; Adult; Follow-Up Studies; Middle Aged; Sensitivity and Specificity; Personality Inventory; Antidepressive Agents; Depressive Disorder; Ambulatory Care; Outcome and Process Assessment (Health Care); Non-U.S. Gov't; Research Support; Comparative Study; Blood Glucose/metabolism; Brain Mapping; Cerebral Cortex/physiopathology/radionuclide imaging; Cognitive Therapy; Emission-Computed; Energy Metabolism/physiology; Fluorodeoxyglucose F18/diagnostic use; Frontal Lobe/physiopathology/radionuclide imaging; Limbic System/physiopathology/radionuclide imaging; Major/physiopathology/radionuclide imaging/therapy; Nerve Net/physiopathology/radionuclide imaging; Neural Pathways/physiopathology/radionuclide imaging; Paroxetine/therapeutic use; Prefrontal Cortex/physiopathology/radionuclide imaging; Second-Generation/therapeutic use; Tomography
Creator
An entity primarily responsible for making the resource
Goldapple K; Segal Z; Garson C; Lau M; Bieling P; Kennedy S; Mayberg H
Description
An account of the resource
BACKGROUND: Functional imaging studies of major depressive disorder demonstrate response-specific regional changes following various modes of antidepressant treatment. OBJECTIVE: To examine changes associated with cognitive behavior therapy (CBT). METHODS: Brain changes underlying response to CBT were examined using resting-state fluorine-18-labeled deoxyglucose positron emission tomography. Seventeen unmedicated, unipolar depressed outpatients (mean +/- SD age, 41 +/- 9 years; mean +/- SD initial 17-item Hamilton Depression Rating Scale score, 20 +/- 3) were scanned before and after a 15- to 20-session course of outpatient CBT. Whole-brain, voxel-based methods were used to assess response-specific CBT effects. A post hoc comparison to an independent group of 13 paroxetine-treated responders was also performed to interpret the specificity of identified CBT effects. RESULTS: A full course of CBT resulted in significant clinical improvement in the 14 study completers (mean +/- SD posttreatment Hamilton Depression Rating Scale score of 6.7 +/- 4). Treatment response was associated with significant metabolic changes: increases in hippocampus and dorsal cingulate (Brodmann area [BA] 24) and decreases in dorsal (BA 9/46), ventral (BA 47/11), and medial (BA 9/10/11) frontal cortex. This pattern is distinct from that seen with paroxetine-facilitated clinical recovery where prefrontal increases and hippocampal and subgenual cingulate decreases were seen. CONCLUSIONS: Like other antidepressant treatments, CBT seems to affect clinical recovery by modulating the functioning of specific sites in limbic and cortical regions. Unique directional changes in frontal cortex, cingulate, and hippocampus with CBT relative to paroxetine may reflect modality-specific effects with implications for understanding mechanisms underlying different treatment strategies.
2004
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1001/archpsyc.61.1.34" target="_blank" rel="noreferrer">10.1001/archpsyc.61.1.34</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2004
Adult
Ambulatory Care
Antidepressive Agents
Archives Of General Psychiatry
Backlog
Bieling P
Blood Glucose/metabolism
Brain Mapping
Cerebral Cortex/physiopathology/radionuclide imaging
Cognitive Therapy
Comparative Study
Depressive Disorder
Emission-Computed
Energy Metabolism/physiology
Female
Fluorodeoxyglucose F18/diagnostic use
Follow-up Studies
Frontal Lobe/physiopathology/radionuclide imaging
Garson C
Goldapple K
Humans
Journal Article
Kennedy S
Lau M
Limbic System/physiopathology/radionuclide imaging
Major/physiopathology/radionuclide imaging/therapy
Male
Mayberg H
Middle Aged
Nerve Net/physiopathology/radionuclide imaging
Neural Pathways/physiopathology/radionuclide imaging
Non-U.S. Gov't
Outcome And Process Assessment (health Care)
Paroxetine/therapeutic use
Personality Inventory
Prefrontal Cortex/physiopathology/radionuclide imaging
Research Support
Second-Generation/therapeutic use
Segal Z
Sensitivity and Specificity
Tomography
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/S0387-7604(03)00113-X" target="_blank" rel="noreferrer">http://doi.org/10.1016/S0387-7604(03)00113-X</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Unilateral closed-lip schizencephaly and epilepsy: a comparison with cases of unilateral polymicrogyria
Publisher
An entity responsible for making the resource available
Brain & Development
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
Subject
The topic of the resource
Child; Female; Humans; Male; Adult; Follow-Up Studies; Magnetic Resonance Imaging; adolescent; Preschool; infant; Q3 Literature Search; Tomography; X-Ray Computed; Electroencephalography; Epilepsy/pathology; Brain/abnormalities/pathology; Frontal Lobe/pathology; Gait Disorders; Neurologic/complications/pathology; Temporal Lobe/pathology
Creator
An entity primarily responsible for making the resource
Caraballo RH; Cersosimo RO; Fejerman N
Description
An account of the resource
We compared the electroclinical features and evolution of patients with two different types of abnormal cortical organization: unilateral closed-lip schizencephaly (SCHZ) and unilateral polymicrogyria (PMG). Between February 1990 and June 2002, 51 children with either unilateral PMG or closed-lip SCHZ were selected through neuroradiological analysis for investigation at our service. We evaluated the frequency of epilepsy, electroclinical features and evolution. The mean time of follow-up was 7 years (range 1-12 years). All patients underwent neurological examination, computed tomography scan and magnetic resonance imaging, serial electroencephalographic (EEG) recordings and neuropsychological assessment. Thirty-six of the 51 patients had unilateral PMG. All patients had hemiparesis with mild spasticity. Mental retardation was mild in 20 and moderate in 14. In two patients IQ was normal. Partial motor seizures were recorded in 28 patients, with secondary generalization in 20. The median age at onset of seizures was 2 years (range 4 months-7 years). Interictal EEGs showed unilateral spikes in all patients. In 21 patients epilepsy worsened between the ages of 4 and 8 (mean 5.6 years) with frequent atonic seizures, atypical absences, epileptic negative myoclonus and gait difficulties. EEGs showed continuous spike-wave activity or bilateral high-frequency spike discharges during slow-wave sleep. Frequent relapses of atonic and myoclonic seizures were seen in nine patients. At present, 16 patients are seizure-free. Fifteen patients with unilateral SCHZ were included in the study. Focal motor seizures were registered in seven cases, in three of them with secondary generalization. The median age at onset of epilepsy was 2.5 years (range 1-4 years). Interictal EEGs showed unilateral spikes in these seven cases. All patients except one presented mild spastic hemiparesis. Mental retardation was mild in ten children, moderate in two and IQ was normal in three. Although the underlying mechanisms leading to PMG and SCHZ are probably similar, the electroclinical phenomenon of secondary bilateral synchrony with frequent negative myoclonus was not present in our cases with unilateral closed-lip SCHZ.
2004
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/S0387-7604(03)00113-X" target="_blank" rel="noreferrer">10.1016/S0387-7604(03)00113-X</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2004
Adolescent
Adult
Backlog
Brain & Development
Brain/abnormalities/pathology
Caraballo RH
Cersosimo RO
Child
Electroencephalography
Epilepsy/pathology
Fejerman N
Female
Follow-up Studies
Frontal Lobe/pathology
Gait Disorders
Humans
Infant
Journal Article
Magnetic Resonance Imaging
Male
Neurologic/complications/pathology
Preschool
Q3 Scoping Review Results
Temporal Lobe/pathology
Tomography
X-Ray Computed
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1097/00005176-200209000-00029" target="_blank" rel="noreferrer">http://doi.org/10.1097/00005176-200209000-00029</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Diagnosis and management of MNGIE syndrome in children: case report and review of the literature
Publisher
An entity responsible for making the resource available
Journal Of Pediatric Gastroenterology And Nutrition
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
Subject
The topic of the resource
Child; Female; Humans; Parenteral Nutrition; adolescent; Tomography; X-Ray Computed; Duodenum/radiography; Gastrointestinal Diseases/physiopathology/radiography/therapy; Mitochondrial Encephalomyopathies/physiopathology/radiography/therapy; Stomach/radiography; Total; Ubiquinone/therapeutic use; Vitamins/therapeutic use
Creator
An entity primarily responsible for making the resource
Teitelbaum JE; Berde CB; Nurko S; Buonomo C; Perez-Atayde AR; Fox VL
Description
An account of the resource
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) syndrome is a rare disorder that presents in childhood; however, marked delay in diagnosis is common. We report a case and review the literature describing the typical features that should alert pediatricians to the diagnosis. We also describe a novel management strategy for providing symptomatic relief.
2002
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/00005176-200209000-00029" target="_blank" rel="noreferrer">10.1097/00005176-200209000-00029</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2002
Adolescent
Backlog
Berde CB
Buonomo C
Child
Duodenum/radiography
Female
Fox VL
Gastrointestinal Diseases/physiopathology/radiography/therapy
Humans
Journal Article
Journal Of Pediatric Gastroenterology And Nutrition
Mitochondrial Encephalomyopathies/physiopathology/radiography/therapy
Nurko S
Parenteral Nutrition
Perez-Atayde AR
Stomach/radiography
Teitelbaum JE
Tomography
Total
Ubiquinone/therapeutic use
Vitamins/therapeutic use
X-Ray Computed
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1111/j.1469-8749.2004.tb00983.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1469-8749.2004.tb00983.x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Joubert syndrome: long-term follow-up
Publisher
An entity responsible for making the resource available
Developmental Medicine And Child Neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
Subject
The topic of the resource
Child; Female; Humans; Male; Prognosis; Follow-Up Studies; Magnetic Resonance Imaging; Tomography; X-Ray Computed; Evoked Potentials; Disease Specific; Achilles Tendon/pathology/physiopathology; Cerebellar Ataxia/physiopathology/radiography; Cerebellum/abnormalities/radiography; Developmental Disabilities/physiopathology/radiography; Eye Movements; Pigment Epithelium of Eye/pathology/physiopathology; Visual
Creator
An entity primarily responsible for making the resource
Hodgkins PR; Harris CM; Shawkat FS; Thompson DA; Chong K; Timms C; Russell-Eggitt I; Taylor DS; Kriss A
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1469-8749.2004.tb00983.x" target="_blank" rel="noreferrer">10.1111/j.1469-8749.2004.tb00983.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2004
2004
Achilles Tendon/pathology/physiopathology
Backlog
Cerebellar Ataxia/physiopathology/radiography
Cerebellum/abnormalities/radiography
Child
Chong K
Developmental Disabilities/physiopathology/radiography
Developmental Medicine and Child Neurology
Disease Specific
Evoked Potentials
Eye Movements
Female
Follow-up Studies
Harris CM
Hodgkins PR
Humans
Journal Article
Kriss A
Magnetic Resonance Imaging
Male
Pigment Epithelium of Eye/pathology/physiopathology
Prognosis
Russell-Eggitt I
Shawkat FS
Taylor DS
Thompson DA
Timms C
Tomography
Visual
X-Ray Computed
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1212/wnl.59.4.490" target="_blank" rel="noreferrer">http://doi.org/10.1212/wnl.59.4.490</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Practice parameter: evaluation of children and adolescents with recurrent headaches: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society
Publisher
An entity responsible for making the resource available
Neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
Subject
The topic of the resource
Child; Female; Humans; Male; Risk Factors; Magnetic Resonance Imaging; Predictive Value of Tests; adolescent; Preschool; Tomography; X-Ray Computed; Electroencephalography; Recurrence; Spinal Puncture; Headache/diagnosis/etiology; Migraine Disorders/diagnosis; Neurologic Examination/standards
Creator
An entity primarily responsible for making the resource
Lewis DW; Ashwal S; Dahl G; Dorbad D; Hirtz D; Prensky A; Jarjour I; Quality Standards Subcommittee of the American Academy of Neurology ; Practice Committee of the Child Neurology Society
Description
An account of the resource
OBJECTIVE: The Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society develop practice parameters as strategies for patient management based on analysis of evidence. For this parameter, the authors reviewed available evidence on the evaluation of the child with recurrent headaches and made recommendations based on this evidence. METHODS: Relevant literature was reviewed, abstracted, and classified. Recommendations were based on a four-tiered scheme of evidence classification. RESULTS: There is inadequate documentation in the literature to support any recommendation as to the appropriateness of routine laboratory studies or performance of lumbar puncture. EEG is not recommended in the routine evaluation, as it is unlikely to define or determine an etiology or distinguish migraine from other types of headaches. In those children undergoing evaluation for recurrent headache found to have a paroxysmal EEG, the risk for future seizures is negligible; therefore, further investigation for epilepsy or treatments aimed at preventing future seizures is not indicated. Obtaining a neuroimaging study on a routine basis is not indicated in children with recurrent headaches and a normal neurologic examination. Neuroimaging should be considered in children with an abnormal neurologic examination or other physical findings that suggest CNS disease. Variables that predicted the presence of a space-occupying lesion included 1) headache of less than 1-month duration; 2) absence of family history of migraine; 3) abnormal neurologic findings on examination; 4) gait abnormalities; and 5) occurrence of seizures. CONCLUSIONS: Recurrent headaches occur commonly in children and are diagnosed on a clinical basis rather than by any testing. The routine use of any diagnostic studies is not indicated when the clinical history has no associated risk factors and the child's examination is normal.
2002
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1212/wnl.59.4.490" target="_blank" rel="noreferrer">10.1212/wnl.59.4.490</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2002
Adolescent
Ashwal S
Backlog
Child
Dahl G
Dorbad D
Electroencephalography
Female
Headache/diagnosis/etiology
Hirtz D
Humans
Jarjour I
Journal Article
Lewis DW
Magnetic Resonance Imaging
Male
Migraine Disorders/diagnosis
Neurologic Examination/standards
Neurology
Practice Committee of the Child Neurology Society
Predictive Value of Tests
Prensky A
Preschool
Quality Standards Subcommittee of the American Academy of Neurology
Recurrence
Risk Factors
Spinal Puncture
Tomography
X-Ray Computed
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1212/wnl.59.7.1058" target="_blank" rel="noreferrer">http://doi.org/10.1212/wnl.59.7.1058</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Neuroanatomy of holoprosencephaly as predictor of function: beyond the face predicting the brain
Publisher
An entity responsible for making the resource available
Neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
Subject
The topic of the resource
Child; Female; Humans; Male; Adult; Prospective Studies; Magnetic Resonance Imaging; Linear Models; Chi-Square Distribution; Forecasting; adolescent; Preschool; infant; Q3 Literature Search; Nonparametric; Statistics; Tomography; Brain/pathology; X-Ray Computed; Face/pathology; Holoprosencephaly/pathology/physiopathology; Seizures/pathology/physiopathology
Creator
An entity primarily responsible for making the resource
Plawner LL; Delgado MR; Miller VS; Levey EB; Kinsman SL; Barkovich AJ; Simon EM; Clegg NJ; Sweet VT; Stashinko EE; Hahn JS
Description
An account of the resource
BACKGROUND: Despite advances in neuroimaging and molecular genetics of holoprosencephaly (HPE), the clinical spectrum of HPE has remained inadequately described. OBJECTIVE: To better characterize the clinical features of HPE and identify specific neuroanatomic abnormalities that may be useful predictors of neurodevelopmental function. METHODS: The authors evaluated 68 children with HPE in a multicenter, prospective study. Neuroimaging studies were assessed for the grade of HPE (lobar, semilobar, and alobar), the degree of nonseparation of the deep gray nuclei, and presence of dorsal cyst or cortical malformation. RESULTS: In general, the severity of clinical problems and neurologic dysfunctions correlated with the degree of hemispheric nonseparation (grade of HPE). Nearly three-quarters of the patients had endocrinopathies, with all having at least diabetes insipidus. The severity of endocrine abnormalities correlated with the degree of hypothalamic nonseparation (p = 0.029). Seizures occurred in approximately half of the children with HPE. The presence of cortical malformations was associated with difficult-to-control seizures. The presence and degree of dystonia correlated with the degree of nonseparation of the caudate and lentiform nuclei and the grade of HPE (p < 0.05). Hypotonia correlated with the grade of HPE (p < 0.05). Mobility, upper extremity function, and language correlated with the degree of nonseparation of the caudate, lentiform and thalamic nuclei, and grade of HPE (p < 0.01). CONCLUSIONS: Patients with HPE manifest a wide spectrum of clinical problems and neurologic dysfunction. The nature and severity of many of these problems can be predicted by specific neuroanatomic abnormalities found in HPE.
2002
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1212/wnl.59.7.1058" target="_blank" rel="noreferrer">10.1212/wnl.59.7.1058</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2002
Adolescent
Adult
Backlog
Barkovich AJ
Brain/pathology
Chi-Square Distribution
Child
Clegg NJ
Delgado MR
Face/pathology
Female
Forecasting
Hahn JS
Holoprosencephaly/pathology/physiopathology
Humans
Infant
Journal Article
Kinsman SL
Levey EB
Linear Models
Magnetic Resonance Imaging
Male
Miller VS
Neurology
Nonparametric
Plawner LL
Preschool
Prospective Studies
Q3 Scoping Review Results
Seizures/pathology/physiopathology
Simon EM
Stashinko EE
Statistics
Sweet VT
Tomography
X-Ray Computed
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1002/ajmg.1320570205" target="_blank" rel="noreferrer">http://doi.org/10.1002/ajmg.1320570205</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Neuronal ceroid-lipofuscinosis: A clinical and morphological study of 19 patients.
Publisher
An entity responsible for making the resource available
American Journal Of Medical Genetics
Date
A point or period of time associated with an event in the lifecycle of the resource
1995
Subject
The topic of the resource
Child; Female; Humans; Male; Adult; Follow-Up Studies; Longitudinal Studies; Magnetic Resonance Imaging; Time Factors; adolescent; Preschool; infant; Tomography; Age of Onset; Atrophy; Brain/pathology/radiography; Cerebellum/pathology; Neuronal Ceroid-Lipofuscinoses/diagnosis/physiopathology; X-Ray Computed
Creator
An entity primarily responsible for making the resource
Nardocci N; Verga ML; Binelli S; Zorzi G; Angelini L; Bugiani O
Description
An account of the resource
We report on clinical, electrophysiological, neuroradiological, and morphological data from 19 patients with different types (late infantile, juvenile, and adult) of neuronal ceroid-lipofuscinosis (NCL), observed in the last 10 years at the Neurological Institute of Milan. Late Infantile NCL (LINCL) (8 patients, 4m/4f). Age at onset: 2-4 1/2 years. Seizures (6 patients) or decline of mental capacities (2 patients) were the presenting symptoms, followed by myoclonus and ataxia; visual loss and optic atrophy occurred in 6 patients within 3 years. All but 2 children became bedridden within 3 1/2 years. CT and MRI demonstrated different degrees of cerebral and cerebellar atrophy within 3 years from onset of the disease. Ultrastructural studies showed fingerprint profiles (FP) and osmiophilic bodies (OB) in circulating lymphocytes; curvilinear bodies (CB) and FP were detected in eccrine secretory cells. Juvenile NCL (JNCL) (7 patients, 4m/3f). Age at onset: 6-9 years. Visual loss with retinal degeneration was the presenting symptoms, accompanied in all but 2 patients by slight mental impairment. Seizures occurred within 2-4 years. CT and MRI detected cerebral or cerebellar atrophy in those patients (5 patients) with a clinical follow-up longer than 4 years. Electron microscopy showed FP on circulating lymphocytes, and both FP and CB on skin biopsy specimens. Adult NCL (ANCL) (4 patients, 3 m/1f). Age at onset: 12-50 years. Progressive myoclonus epilepsy (1 patient) or dementia with motor disturbances (3 patients) were the clinical phenotypes of the disease. MRI demonstrated cerebral and cerebellar atrophy within 6 years from onset. Electron microscopy disclosed FP in cytoplasmic vacuoles inside eccrine secretory cells.
1995
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/ajmg.1320570205" target="_blank" rel="noreferrer">10.1002/ajmg.1320570205</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1995
Adolescent
Adult
Age of Onset
American Journal Of Medical Genetics
Angelini L
Atrophy
Backlog
Binelli S
Brain/pathology/radiography
Bugiani O
Cerebellum/pathology
Child
Female
Follow-up Studies
Humans
Infant
Journal Article
Longitudinal Studies
Magnetic Resonance Imaging
Male
Nardocci N
Neuronal Ceroid-Lipofuscinoses/diagnosis/physiopathology
Preschool
Time Factors
Tomography
Verga ML
X-Ray Computed
Zorzi G
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1002/ana.410340107" target="_blank" rel="noreferrer">http://doi.org/10.1002/ana.410340107</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes (MELAS): clinical, radiological, pathological, and genetic observations
Publisher
An entity responsible for making the resource available
Annals Of Neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
Subject
The topic of the resource
Child; Female; Humans; Male; Molecular Sequence Data; Preschool; infant; Q3 Literature Search; Tomography; X-Ray Computed; Base Sequence; Capillaries/pathology; DNA/analysis; Electron; MELAS Syndrome/genetics/pathology/radiography; Microscopy; Mitochondria/pathology; Muscles/pathology
Creator
An entity primarily responsible for making the resource
Koo B; Becker LE; Chuang S; Merante F; Robinson BH; MacGregor D; Tein I; Ho VB; McGreal DA; Wherrett JR
Description
An account of the resource
We reviewed 10 patients (5 males, 5 females) with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes. The age of symptom onset ranged from 3 months to 12 years. All had lactic acidosis, multiple stroke-like events with secondary neurological deficits, radiological changes of progressive brain infarction, and muscle biopsy showing ragged-red fibers. In patients with earlier onset of symptoms (< 2 yr), involvement tended to be more diffuse, with failure to thrive and early onset of delayed development. Patients whose symptoms appeared later tended to have focal neurological deficits with migraine-like headache, and a rate of cognitive regression reflecting the rapidity of disease progression. Radiological changes included multiple areas of infarction with initial predilection for parietal occipital areas, progressing to generalized atrophy. Pathological findings in muscle biopsies included type 1 fiber predominance, ragged-red fibers, increased intermyofibrillar lipid deposition, and abnormal mitochondria. Four patients showed mitochondrial DNA tRNA mutation at position 3,243. No difference was noted in clinical, radiological, or pathological findings in patients with and without this mutation, suggesting that multiple sites of point mutation may give rise to mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes.
1993
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/ana.410340107" target="_blank" rel="noreferrer">10.1002/ana.410340107</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1993
Annals Of Neurology
Backlog
Base Sequence
Becker LE
Capillaries/pathology
Child
Chuang S
DNA/analysis
Electron
Female
Ho VB
Humans
Infant
Journal Article
Koo B
MacGregor D
Male
McGreal DA
MELAS Syndrome/genetics/pathology/radiography
Merante F
Microscopy
Mitochondria/pathology
Molecular Sequence Data
Muscles/pathology
Preschool
Q3 Scoping Review Results
Robinson BH
Tein I
Tomography
Wherrett JR
X-Ray Computed
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1007/bf00598955" target="_blank" rel="noreferrer">http://doi.org/10.1007/bf00598955</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Tay-Sachs disease: Progression of changes on neuroimaging in four cases.
Publisher
An entity responsible for making the resource available
Neuroradiology
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
Subject
The topic of the resource
Child; Humans; Male; Follow-Up Studies; Longitudinal Studies; Magnetic Resonance Imaging; Preschool; infant; Brain Diseases; Emission-Computed; Tomography; Brain/pathology; Atrophy; X-Ray Computed; Demyelinating Diseases/diagnosis/pathology; Metabolic/diagnosis/pathology; Tay-Sachs Disease/diagnosis/pathology
Creator
An entity primarily responsible for making the resource
Fukumizu M; Yoshikawa H; Takashima S; Sakuragawa N; Kurokawa T
Description
An account of the resource
The neuroradiological findings in four patients with Tay-Sachs disease are described in three phases of the clinical course. The basal ganglia and cerebral white matter show low density on computed tomography and high signal intensity on T2-weighted magnetic resonance imaging in the initial phase. The caudate nuclei are characteristically enlarged and protrude into the lateral ventricles in the first and second phases. The cerebral white matter shows low density on the CT which varies in extent from the second to third phases, and the whole brain becomes atrophic in the last phase. Thus, central nervous system involvement in the disease may begin in basal ganglia as well as in cerebral white matter.
1992
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/bf00598955" target="_blank" rel="noreferrer">10.1007/bf00598955</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1992
Atrophy
Backlog
Brain Diseases
Brain/pathology
Child
Demyelinating Diseases/diagnosis/pathology
Emission-Computed
Follow-up Studies
Fukumizu M
Humans
Infant
Journal Article
Kurokawa T
Longitudinal Studies
Magnetic Resonance Imaging
Male
Metabolic/diagnosis/pathology
Neuroradiology
Preschool
Sakuragawa N
Takashima S
Tay-Sachs Disease/diagnosis/pathology
Tomography
X-Ray Computed
Yoshikawa H
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/0387-7604(94)90077-9" target="_blank" rel="noreferrer">http://doi.org/10.1016/0387-7604(94)90077-9</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Acute onset of X-linked adrenoleukodystrophy mimicking encephalitis
Publisher
An entity responsible for making the resource available
Brain & Development
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
Subject
The topic of the resource
Humans; Male; Acute Disease; infant; Q3 Literature Search; Tomography; Diagnosis; Differential; X-Ray Computed; Adrenoleukodystrophy/diagnosis/drug therapy/genetics; Encephalitis/diagnosis; Erucic Acids/therapeutic use; Fatty Acids/blood; Linkage (Genetics); X Chromosome
Creator
An entity primarily responsible for making the resource
Zammarchi E; Donati MA; Tucci F; Fonda C; Fanelli F; Pazzaglia R
Description
An account of the resource
We report the case of a 6-year-old boy with X-linked adrenoleukodystrophy (ALD). In view of the acute onset of vomiting, fever, and coma, encephalitis was initially suspected. However, brain magnetic resonance imaging demonstrated a pattern of demyelination that was consistent with ALD; this diagnosis was confirmed by the finding of elevated plasma very long-chain fatty acids levels. At presentation, the patient was hyponatremic. That this metabolic disturbance and the coma resolved within hours of the initiation of corticosteroid therapy suggests that the presenting symptoms were secondary to adrenal cortical insufficiency. Primary adrenal failure was confirmed by endocrinologic evaluation. Thrombocytopenia, hepatic transaminase abnormalities, anemia and leukopenia developed during the subsequent course of therapy with oleic acid and erucic acid.
1994
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0387-7604(94)90077-9" target="_blank" rel="noreferrer">10.1016/0387-7604(94)90077-9</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1994
Acute Disease
Adrenoleukodystrophy/diagnosis/drug therapy/genetics
Backlog
Brain & Development
Diagnosis
Differential
Donati MA
Encephalitis/diagnosis
Erucic Acids/therapeutic use
Fanelli F
Fatty Acids/blood
Fonda C
Humans
Infant
Journal Article
Linkage (Genetics)
Male
Pazzaglia R
Q3 Scoping Review Results
Tomography
Tucci F
X Chromosome
X-Ray Computed
Zammarchi E
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s0387-7604(96)00558-x" target="_blank" rel="noreferrer">http://doi.org/10.1016/s0387-7604(96)00558-x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Recurrent pain attacks in a 3-year-old patient with myoclonus epilepsy associated with ragged-red fibers (MERRF): a single-photon emission computed tomographic (SPECT) and electrophysiological study
Publisher
An entity responsible for making the resource available
Brain & Development
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
Subject
The topic of the resource
Child; Female; Humans; Magnetic Resonance Imaging; Preschool; Q3 Literature Search; Emission-Computed; Tomography; Evoked Potentials; Epilepsies; Recurrence; Pain/diagnosis/drug therapy/etiology; Single-Photon; Somatosensory/physiology; Cytochrome c Group/pharmacology; Flavin Mononucleotide/pharmacology; MERRF Syndrome/complications/diagnosis/physiopathology; Myoclonic/complications/physiopathology/radionuclide imaging; Thalamus/blood supply; Thiamine/pharmacology
Creator
An entity primarily responsible for making the resource
Tanaka S; Osari S; Ozawa M; Yamanouchi H; Goto Y; Matsuda H; Nonaka I
Description
An account of the resource
We reported a 3-year-old girl with myoclonus epilepsy associated with ragged-red fibers (MERRF) who was afflicted with recurrent pain attacks and allodynia on the right side of the body. Although magnetic resonance imaging showed normal intensity in the thalamus, single-photon emission computed tomography (SPECT) revealed hypoperfusion in the thalamus. Somatosensory evoked potentials showed delayed early cortical responses, particularly on right median nerve stimulation. The parenteral administration of cytochrome c with flavin mononucleotide and thiamine diphosphate abolished the intolerable pain. This clinical improvement was objectively supported by the results of SPECT and neurophysiological findings. These observations suggested that a dysfunction of the thalamus was responsible for her pain and that cytochrome c therapy was of benefit for this symptom.
1997
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0387-7604(96)00558-x" target="_blank" rel="noreferrer">10.1016/s0387-7604(96)00558-x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1997
Backlog
Brain & Development
Child
Cytochrome c Group/pharmacology
Emission-Computed
Epilepsies
Evoked Potentials
Female
Flavin Mononucleotide/pharmacology
Goto Y
Humans
Journal Article
Magnetic Resonance Imaging
Matsuda H
MERRF Syndrome/complications/diagnosis/physiopathology
Myoclonic/complications/physiopathology/radionuclide imaging
Nonaka I
Osari S
Ozawa M
Pain/diagnosis/drug therapy/etiology
Preschool
Q3 Scoping Review Results
Recurrence
Single-Photon
Somatosensory/physiology
Tanaka S
Thalamus/blood supply
Thiamine/pharmacology
Tomography
Yamanouchi H
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1038/jcbfm.1994.17" target="_blank" rel="noreferrer">http://doi.org/10.1038/jcbfm.1994.17</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Brain metabolism during short-term starvation in humans
Publisher
An entity responsible for making the resource available
Journal Of Cerebral Blood Flow And Metabolism
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
Subject
The topic of the resource
Female; Humans; Male; Adult; Time Factors; Tissue Distribution; Non-U.S. Gov't; Research Support; Emission-Computed; Tomography; Brain/metabolism; Starvation/metabolism; Blood Glucose/analysis; Ketone Bodies/metabolism; Arteries; Deoxyglucose/analogs & derivatives/metabolism; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose/metabolism; Osmolar Concentration
Creator
An entity primarily responsible for making the resource
Hasselbalch SG; Knudsen GM; Jakobsen J; Hageman LP; Holm S; Paulson OB
Description
An account of the resource
During prolonged starvation, brain energy requirements are covered in part by the metabolism of ketone bodies. It is unknown whether short-term starvation of a few days' duration may lead to reduced brain glucose metabolism due to the change toward ketone body consumption. In the present study we measured the cerebral metabolism of glucose and ketone bodies in nine healthy volunteers before and after 3.5 days of starvation. Regional glucose metabolism was measured by dynamic positron emission tomography using [18F]2-fluoro-2-deoxy-D-glucose. The mean value of K1* in gray and white matter increased by 12% (p < 0.05), whereas k2* and k3* were unchanged compared with control values. Regional glucose metabolism in cortical gray matter was reduced by 26% from 0.294 +/- 0.054 to 0.217 +/- 0.040 mumol g-1 min-1 (p < 0.001). White matter glucose metabolism decreased by 27% (p < 0.02). The decrease was uniform in gray and white matter with regional decreases ranging from 24 to 30%. A determination using Fick's principle confirmed the reduction in glucose metabolism yielding a decrease of 24% from 0.307 +/- 0.050 to 0.233 +/- 0.073 mumol g-1 min-1 (p < 0.05), whereas CBF did not change (0.57 +/- 0.07 vs. 0.57 +/- 0.06 ml g-1 min-1). The global net uptake of beta-hydroxybutyrate increased 13-fold from 0.012 +/- 0.024 to 0.155 +/- 0.140 mumol g-1 min-1 (p < 0.05). Net uptake of acetoacetate and net efflux of lactate and pyruvate did not change significantly during starvation. The present study shows that the human brain adapts to the changes in energy supply as early as 3 days following initiation of starvation, at which time ketone bodies account for approximately one-fourth of the cerebral energy requirements.
1994
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1038/jcbfm.1994.17" target="_blank" rel="noreferrer">10.1038/jcbfm.1994.17</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1994
Adult
Arteries
Backlog
Blood Glucose/analysis
Brain/metabolism
Deoxyglucose/analogs & derivatives/metabolism
Emission-Computed
Female
Fluorine Radioisotopes
Fluorodeoxyglucose F18
Glucose/metabolism
Hageman LP
Hasselbalch SG
Holm S
Humans
Jakobsen J
Journal Article
Journal Of Cerebral Blood Flow And Metabolism
Ketone Bodies/metabolism
Knudsen GM
Male
Non-U.S. Gov't
Osmolar Concentration
Paulson OB
Research Support
Starvation/metabolism
Time Factors
Tissue Distribution
Tomography
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1111/j.1651-2227.1995.tb13616.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1651-2227.1995.tb13616.x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Late onset globoid cell leukodystrophy (Krabbe's disease)--Swedish case with 15 years of follow-up.
Publisher
An entity responsible for making the resource available
Acta Paediatrica
Date
A point or period of time associated with an event in the lifecycle of the resource
1995
Subject
The topic of the resource
Humans; Male; Adult; Follow-Up Studies; Longitudinal Studies; Sweden; Tomography; Age of Onset; X-Ray Computed; Leukodystrophy; Vision Disorders/etiology; Epilepsy/etiology; Galactosylceramidase/blood; Globoid Cell/complications/enzymology/radiography; Musculoskeletal Equilibrium
Creator
An entity primarily responsible for making the resource
Arvidsson J; Hagberg B; Mansson JE; Svennerholm L
Description
An account of the resource
We describe a male patient with late onset globoid cell leukodystrophy (GLD) (Krabbe's disease) still alive at 24 years of age, with a well preserved intellectual and communicative capacity, in contrast to visual failure and severe central pyramidal and extrapyramidal motor disability with spasticity, dystonia, ataxia and peripheral neuropathy. Visual dysfunction began at 4 years of age, limping and balance problems at 8 years and epilepsy at 14 years of age. Neuroimaging at 15 years of age revealed white matter lesions, and nerve conduction velocity examinations showed a slowly developing polyneuropathy. Galactosylceramidase activity was reduced in leukocytes to 0.07 mu kat/kg protein compared with 0.02 (SD 0.01) mu kat/kg protein in infantile GLD.
1995
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1651-2227.1995.tb13616.x" target="_blank" rel="noreferrer">10.1111/j.1651-2227.1995.tb13616.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1995
Acta Paediatrica
Adult
Age of Onset
Arvidsson J
Backlog
Epilepsy/etiology
Follow-up Studies
Galactosylceramidase/blood
Globoid Cell/complications/enzymology/radiography
Hagberg B
Humans
Journal Article
Leukodystrophy
Longitudinal Studies
Male
Mansson JE
Musculoskeletal Equilibrium
Svennerholm L
Sweden
Tomography
Vision Disorders/etiology
X-Ray Computed
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1136/jnnp.56.8.900" target="_blank" rel="noreferrer">http://doi.org/10.1136/jnnp.56.8.900</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Mitochondrial encephalomyopathy: variable clinical expression within a single kindred
Publisher
An entity responsible for making the resource available
Journal Of Neurology, Neurosurgery, And Psychiatry
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
Subject
The topic of the resource
Child; Female; Humans; Male; Adult; Aged; Middle Aged; adolescent; Preschool; Q3 Literature Search; Tomography; Pedigree; X-Ray Computed; DNA/analysis; Brain/radiography; Mitochondrial Encephalomyopathies/genetics/pathology/radiography; Muscles/pathology/ultrastructure
Creator
An entity primarily responsible for making the resource
Crimmins D; Morris JG; Walker GL; Sue CM; Byrne E; Stevens S; Jean-Francis B; Yiannikas C; Pamphlett R
Description
An account of the resource
The clinical manifestations of mitochondrial encephalomyopathy are described in four generations of a single kindred. The age of onset of major neurological disturbance varied from 3-70 years. In some patients, deafness was the only manifestation; in others, recurrent bouts of status epilepticus associated with focal neurological deficits and headache, caused severe disability or death. Examples of all three adult forms of mitochondrial encephalomyopathy: MELAS, MERFF and Kearns Sayre syndrome, were represented within the kindred. Associated features included deafness, short stature, non-insulin-dependent diabetes mellitus, migraine, peptic ulceration and severe constipation. The nt 3243 A-G MELAS mutation was detected in two members of the kindred. This study highlights the diversity of clinical expression of a mitochondrial mutation within a single kindred.
1993
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1136/jnnp.56.8.900" target="_blank" rel="noreferrer">10.1136/jnnp.56.8.900</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1993
Adolescent
Adult
Aged
Backlog
Brain/radiography
Byrne E
Child
Crimmins D
DNA/analysis
Female
Humans
Jean-Francis B
Journal Article
Journal Of Neurology, Neurosurgery, And Psychiatry
Male
Middle Aged
Mitochondrial Encephalomyopathies/genetics/pathology/radiography
Morris JG
Muscles/pathology/ultrastructure
Pamphlett R
Pedigree
Preschool
Q3 Scoping Review Results
Stevens S
Sue CM
Tomography
Walker GL
X-Ray Computed
Yiannikas C