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Text
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Citation List Month
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URL Address
<a href="http://doi.org/10.1007/bf00598955" target="_blank" rel="noreferrer">http://doi.org/10.1007/bf00598955</a>
Dublin Core
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Title
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Tay-Sachs disease: Progression of changes on neuroimaging in four cases.
Publisher
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Neuroradiology
Date
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1992
Subject
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Child; Humans; Male; Follow-Up Studies; Longitudinal Studies; Magnetic Resonance Imaging; Preschool; infant; Brain Diseases; Emission-Computed; Tomography; Brain/pathology; Atrophy; X-Ray Computed; Demyelinating Diseases/diagnosis/pathology; Metabolic/diagnosis/pathology; Tay-Sachs Disease/diagnosis/pathology
Creator
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Fukumizu M; Yoshikawa H; Takashima S; Sakuragawa N; Kurokawa T
Description
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The neuroradiological findings in four patients with Tay-Sachs disease are described in three phases of the clinical course. The basal ganglia and cerebral white matter show low density on computed tomography and high signal intensity on T2-weighted magnetic resonance imaging in the initial phase. The caudate nuclei are characteristically enlarged and protrude into the lateral ventricles in the first and second phases. The cerebral white matter shows low density on the CT which varies in extent from the second to third phases, and the whole brain becomes atrophic in the last phase. Thus, central nervous system involvement in the disease may begin in basal ganglia as well as in cerebral white matter.
1992
Identifier
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<a href="http://doi.org/10.1007/bf00598955" target="_blank" rel="noreferrer">10.1007/bf00598955</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1992
Atrophy
Backlog
Brain Diseases
Brain/pathology
Child
Demyelinating Diseases/diagnosis/pathology
Emission-Computed
Follow-up Studies
Fukumizu M
Humans
Infant
Journal Article
Kurokawa T
Longitudinal Studies
Magnetic Resonance Imaging
Male
Metabolic/diagnosis/pathology
Neuroradiology
Preschool
Sakuragawa N
Takashima S
Tay-Sachs Disease/diagnosis/pathology
Tomography
X-Ray Computed
Yoshikawa H