Subject
PedPal Lit; 'improved' or 'unchanged'. The secondary pH-metric outcome of the number of reflux episodes; a good or excellent result was obtained in 93% of the domperidone group compared with 33% of the controls (P < 0.05). In the trial undertaken by de Loore; after 2 weeks of treatment 75% of patients treated with domperidone were found not to be vomiting; and reference citations of the RCTs that had been found electronically. RESULTS: Four RCTs were identified. Only the two older trials showed any benefits of domperidone on clinical symptoms of GORD in older children; Antiemetics/therapeutic use Child Child; compared with 43% in the metoclopramide group and 7% in the placebo group. The trial by Corraccio gave no detailed results regarding the primary outcomes of effect of domperidone on symptoms but simply reported 'cured'; drug therapy Humans Infant Randomized Controlled Trials/methods Research Design Treatment Outcome; Medline (Pub-med) 1966 to present and Embase from 1974 to 2004; Preschool Domperidone/; the widespread use of unlicensed medicines for GOR is not warranted.; therapeutic use Dopamine Antagonists/; therapeutic use Evidence-Based Medicine Gastroesophageal Reflux/; there was no robust evidence of efficacy for the treatment of GOR with domperidone in young children. Given the usually benign nature of the condition; was reduced with domperidone. CONCLUSION: From the limited evidence available; which were the primary outcome measures. In the trial undertaken by Clara