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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1017/s001216220400132x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1017/s001216220400132x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Systematic review of melatonin treatment in children with neurodevelopmental disabilities and sleep impairment
Publisher
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Developmental Medicine and Child Neurology
Date
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2004
Subject
The topic of the resource
Child; Humans; Wakefulness/physiology; Brain/physiopathology; Melatonin/therapeutic use; Antioxidants/therapeutic use; Developmental Disabilities/drug therapy/epidemiology/physiopathology; Sleep Wake Disorders/epidemiology; sleep disturbance/disorders; Rett syndrome; pharmacologic intervention; melatonin
Creator
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Phillips L; Appleton R E
Description
An account of the resource
Sleep disturbances in children with neurodevelopmental disabilities are common and frequently difficult to treat with conventional pharmacological and behavioural methods. Melatonin is a pineal hormone known to be important in the regulation of the circadian rhythm, including the sleep-wake cycle. This systematic review of available evidence from randomized clinical trials assesses whether melatonin plays a beneficial role in these children and, in particular, its effect on total sleep time, time to sleep onset (sleep latency), and number of awakenings. We also looked at a parental view of the effect. Randomized clinical trials were identified where oral melatonin was compared with a placebo in children with any type of neurodevelopmental disability and associated sleep disturbance. Only three studies, reporting a total of 35 children, fulfilled the criteria for inclusion. The two studies that reported time to sleep onset showed a significant decrease (p<0.05) in this specific outcome where melatonin was compared with a placebo. There was no significant effect of melatonin compared with a placebo on the other outcome measures of total sleep time, night-time awakenings, and parental opinions. Despite the extremely limited randomized clinical trial data, melatonin appears to remain a commonly prescribed drug for disturbed sleep in children with neurodevelopmental abnormalities.
Identifier
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<a href="http://doi.org/10.1017/s001216220400132x" target="_blank" rel="noreferrer noopener">10.1017/s001216220400132x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2004
Antioxidants/therapeutic use
Appleton R E
Brain/physiopathology
Child
Developmental Disabilities/drug therapy/epidemiology/physiopathology
Developmental Medicine and Child Neurology
Humans
melatonin
Melatonin/therapeutic use
pharmacologic intervention
Phillips L
Rett syndrome
sleep disturbance/disorders
Sleep Wake Disorders/epidemiology
Wakefulness/physiology
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1365-2788.2008.01047.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1365-2788.2008.01047.x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Health and sleep problems in Cornelia de Lange Syndrome: a case control study
Publisher
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Journal of Intellectual Disability Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2008
Subject
The topic of the resource
Male; Severity of Illness Index; Case-Control Studies; Comorbidity; Surveys and Questionnaires; Humans; Adolescent; Prevalence; Female; Health Status; De Lange Syndrome/epidemiology/psychology; Ear Diseases/epidemiology/psychology; Eye Diseases/epidemiology/psychology; Gastrointestinal Diseases/epidemiology/psychology; Hernia/epidemiology/psychology; Intellectual Disability/epidemiology/psychology; Self-Injurious Behavior/epidemiology/psychology; Skin Diseases/epidemiology/psychology; Sleep Wake Disorders/epidemiology; Stomatognathic Diseases/epidemiology/psychology; behavioral problems; sleep disturbance; De Lange syndrome; trajectory; characteristics; self-injury
Creator
An entity primarily responsible for making the resource
Hall S; Arron K; Sloneem J; Oliver C
Description
An account of the resource
BACKGROUND: Self-injury, sleep problems and health problems are commonly reported in Cornelia de Lange Syndrome (CdLS) but there are no comparisons with appropriately matched participants. The relationship between these areas and comparison to a control group is warranted. METHOD: 54 individuals with CdLS were compared with 46 participants with intellectual disability (ID) of mixed aetiology who were similar in terms of degree of ID, mobility, age and gender using informant-based measures of health problems, sleep and self-injury. RESULTS: Participants with CdLS experienced significantly more current and lifetime health problems with eye problems and gastrointestinal disorders prominent. Although 55% of those with CdLS experienced sleep problems this prevalence was not different from the comparison group. Sleep disorder was not associated with self-injury in the CdLS group, skin problems were associated with severity of self-injury but not presence. DISCUSSION: People with CdLS experience a range of significant health problems and have more health concerns than others with the same degree of ID. Although this has been well documented in the past, the current high prevalence of health concerns indicates the need for regular health assessment and appropriate intervention.
Identifier
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<a href="http://doi.org/10.1111/j.1365-2788.2008.01047.x" target="_blank" rel="noreferrer noopener">10.1111/j.1365-2788.2008.01047.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2008
Adolescent
Arron K
behavioral problems
Case-Control Studies
characteristics
Comorbidity
De Lange syndrome
De Lange Syndrome/epidemiology/psychology
Ear Diseases/epidemiology/psychology
Eye Diseases/epidemiology/psychology
Female
Gastrointestinal Diseases/epidemiology/psychology
Hall S
Health Status
Hernia/epidemiology/psychology
Humans
Intellectual Disability/epidemiology/psychology
Journal Of Intellectual Disability Research
Male
Oliver C
Prevalence
Self-Injurious Behavior/epidemiology/psychology
self-injury
Severity Of Illness Index
Skin Diseases/epidemiology/psychology
sleep disturbance
Sleep Wake Disorders/epidemiology
Sloneem J
Stomatognathic Diseases/epidemiology/psychology
Surveys And Questionnaires
Trajectory