1
40
4
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.23736/S0026-4946.16.04282-1" target="_blank" rel="noreferrer noopener">http://doi.org/10.23736/S0026-4946.16.04282-1</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Sleep disordered breathing in a cohort of children with achondroplasia: correlation between clinical and instrumental findings
Publisher
An entity responsible for making the resource available
Minerva Pediatrica
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Age Factors; Male; Surveys and Questionnaires; Child; Humans; Cohort Studies; Female; Child Preschool; Infant; Incidence; Sleep Apnea Syndromes/di [Diagnosis]; Sleep Apnea Syndromes/et [Etiology]; Achondroplasia/co [Complications]; Polysomnography/mt [Methods]; Receptor Fibroblast Growth Factor Type 3/ge [Genetics]; Sleep Apnea Syndromes/ep [Epidemiology]; Achondroplasia/ge [Genetics]; EC 2-7-10-1 (FGFR3 protein human); EC 2-7-10-1 (Receptor Fibroblast Growth Factor Type 3); feeding difficulties; Achondroplasia; trajectory; characteristics; respiratory sleep disorder
Creator
An entity primarily responsible for making the resource
Zaffanello M; Lo Tartaro P; Piacentini G; Cantalupo G; Gasperi E; Antoniazzi F
Description
An account of the resource
BACKGROUND: The aim of the present study was to show the results of an overnight polysomnography in a cohort of 9 children (7 females and 2 males) with achondroplasia, aged between 1 and 12 years (5.56+/-4.7 years). All of the children carried the Gly380Arg (G380R) mutation on the FGFR3 gene. METHODS: All the young patients underwent nocturnal polysomnography without sleep deprivation. Sleep staging was noted according to the guidelines of the American Academy of Sleep Medicine. At the time of registration, the parents answered to a Sleep Control Test questionnaire regarding medical history and diurnal and nocturnal symptoms of their children. RESULTS: Respiratory sleep disorder was present in 78% of cases, and was generally mild. In 67% of the children there was respiratory effort for more than 30% of the total sleep time. The sample was divided into two age categories: 5 children under the age of 3 years and 4 children over 10 years old. A higher incidence of sleep disorder was found in the first few years of life, where the obstructive pattern predominates. Regarding sleep architecture, we did not find macroscopic alterations of sleep architecture and its phasic manifestations in our paediatric group. However, parents have not been referred daytime sleepiness, attention deficiency, hyperactivity and nocturnal enuresis. Only one had referred recurrent respiratory infections. CONCLUSIONS: Polysomnography is a very useful tool in the evaluation of sleep-disordered breathing in children with achondroplasia.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.23736/S0026-4946.16.04282-1" target="_blank" rel="noreferrer noopener">10.23736/S0026-4946.16.04282-1</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
achondroplasia
Achondroplasia/co [Complications]
Achondroplasia/ge [Genetics]
Age Factors
Antoniazzi F
Cantalupo G
characteristics
Child
Child Preschool
Cohort Studies
EC 2-7-10-1 (FGFR3 protein human)
EC 2-7-10-1 (Receptor Fibroblast Growth Factor Type 3)
feeding difficulties
Female
Gasperi E
Humans
Incidence
Infant
Lo Tartaro P
Male
Minerva Pediatrica
Piacentini G
Polysomnography/mt [Methods]
Receptor Fibroblast Growth Factor Type 3/ge [Genetics]
respiratory sleep disorder
Sleep Apnea Syndromes/di [Diagnosis]
Sleep Apnea Syndromes/ep [Epidemiology]
Sleep Apnea Syndromes/et [Etiology]
Surveys And Questionnaires
Trajectory
Zaffanello M
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/ajmg.1320590412" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ajmg.1320590412</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of obstructive sleep apnea in achondroplasia: evaluation of sleep, breathing, and somatosensory-evoked potentials
Publisher
An entity responsible for making the resource available
American Journal of Medical Genetics
Date
A point or period of time associated with an event in the lifecycle of the resource
1995
Subject
The topic of the resource
Achondroplasia/co [Complications]; Adolescent; Adult Child; Child; Preschool; Evoked Potentials; Female; Humans; Infant; Male; Middle Aged; Respiration; Sleep Apnea Syndromes/et [Etiology]; Sleep Apnea Syndromes/th [Therapy]; Tonsillectomy; Weight Loss; breathing difficulties; achondroplasia; surgical interventions; physical interventions; adenotonsillectomy; losing weight; weight loss; CPAP; respiratory disturbance index
Creator
An entity primarily responsible for making the resource
Waters K A; Everett F; Sillence D O; Fagan E R; Sullivan C E
Description
An account of the resource
The occurrence of obstructive sleep apnea (OSA) is achondroplasia has been linked to brain stem compression. Overnight sleep studies (11 subjects) and somatosensory-evoked potentials (SEP's, 10 subjects) were recorded before and after conventional treatment of OSA in achondroplasia. The two groups were derived from 30 subjects who underwent diagnostic sleep studies and SEPs, including 15 females and 15 males with a median age 6.6 years (range 1.0-47.6) at the time of the first study. In 30 initial studies there was no correlation between severity of OSA and abnormalities on SEP evaluation. Treatment of 17 subjects included adenotonsillectomy (n = 3), weight loss (n = 1), and nasal-mask continuous positive airway pressure (CPAP) (n = 13). Sleep studies in 11 subjects after a delay of 8.8 +/- 2.8 months showed a reduction in respiratory disturbance index (RDI) from 38.4 +/- 6.9 to 6.5 +/- 1.8 events hr(-1) (p < 0.001) and movements/arousals fell from 10.4 +/- 2.2 to 4.8 +/- 0.2 hr(-1) (p < 0.04). Obstructive events were reduced from 33.7 +/- 6.9 to 2.4 +/- 1.0 hr(-1) (p < 0.001). Improvement of respiratory indices was associated with an increased proportion of slow-wave sleep from 25.2 +/- 4.0% to 32.3 +/- 2.4% (p = 0.01), and decrease in stage 1-2 sleep from 59.3 +/- 5.8% to 46.6 +/- 1.9% (p = 0.03). There was no increase in the percentage of REM sleep (15.2 to 21.2%). Repeat SEP studies in 10 subjects, after clinically effective treatment of OSA, showed improvement of SEP score of at least 1 grade, in 5 of 7 (71%) with initially abnormal values. We conclude that treatment of relieve upper airway obstruction improves OSA in achondroplasia, accompanied by changes in sleep structure and, in some cases, improved studies of neurological function.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/ajmg.1320590412" target="_blank" rel="noreferrer noopener">10.1002/ajmg.1320590412</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
1995
achondroplasia
Achondroplasia/co [Complications]
adenotonsillectomy
Adolescent
Adult Child
American Journal Of Medical Genetics
breathing difficulties
Child
CPAP
Everett F
Evoked Potentials
Fagan E R
Female
Humans
Infant
losing weight
Male
Middle Aged
physical interventions
Preschool
Respiration
respiratory disturbance index
Sillence D O
Sleep Apnea Syndromes/et [Etiology]
Sleep Apnea Syndromes/th [Therapy]
Sullivan C E
surgical interventions
Tonsillectomy
Waters K A
Weight Loss
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1097/00005792-198807000-00002" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/00005792-198807000-00002</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Respiratory complications of mucopolysaccharide storage disorders
Publisher
An entity responsible for making the resource available
Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
1988
Subject
The topic of the resource
Male; Child; Humans; Adult; Adolescent; Female; Child Preschool; Infant; Retrospective Studies; Sleep Apnea Syndromes/et [Etiology]; Mucopolysaccharidoses/co [Complications]; Respiratory Tract Diseases/et [Etiology]; Airway Obstruction/et [Etiology]; Anesthesia General/ae [Adverse Effects]; Cardiovascular Diseases/et [Etiology]; Intubation Intratracheal/ae [Adverse Effects]; Lung Diseases/et [Etiology]; Lung Diseases/pp [Physiopathology]; Mucopolysaccharidoses/mo [Mortality]; Mucopolysaccharidoses/pp [Physiopathology]; Respiratory Tract Diseases/pp [Physiopathology]; Respiratory Tract Diseases/ra [Radiography]; Spinal Diseases/et [Etiology]; Spinal Diseases/ra [Radiography]; breathing difficulties; MLII; MLIII; MPSI; MPSII; MPSVI; surgical interventions; pharmacologic interventions; tonsillectomy; adenoidectomy; tracheostomy; diuretics; theophylline; digoxin; beta adrenergic blockers; calcium antagonists; respiratory problems
Creator
An entity primarily responsible for making the resource
Semenza G L; Pyeritz R E
Description
An account of the resource
Twenty-one patients with the diagnosis of mucopolysaccharidosis or mucolipidosis and a history of respiratory complaints or thorough respiratory evaluation were studied retrospectively. Anatomic factors affecting respiratory status included: (i) upper airway narrowing by hypertrophied tongue, tonsils, adenoids, and mucous membranes; (ii) lower airway narrowing by glycosaminoglycan deposition within the tracheobronchial mucosa; (iii) decreased thoracic dimensions due to scoliosis and thoracic hyperkyphosis; and (iv) decreased abdominal dimensions due to lumbar hyperlordosis, gibbus formation and hepatosplenomegaly. Cardiac and neurologic involvement, while present, did not play primary roles in the development of respiratory disease. The functional consequences of these findings included increased risk of developing: (i) respiratory tract infections; (ii) airway compromise during or after anesthesia or sedation; (iii) dyspnea on exertion; (iv) obstructive lung disease; (v) obstructive sleep apnea; and (vi) cor pulmonale. A management approach is presented which can reduce the morbidity and mortality experienced by these patients.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/00005792-198807000-00002" target="_blank" rel="noreferrer noopener">10.1097/00005792-198807000-00002</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
1988
adenoidectomy
Adolescent
Adult
Airway Obstruction/et [Etiology]
Anesthesia General/ae [Adverse Effects]
beta adrenergic blockers
breathing difficulties
calcium antagonists
Cardiovascular Diseases/et [Etiology]
Child
Child Preschool
digoxin
diuretics
Female
Humans
Infant
Intubation Intratracheal/ae [Adverse Effects]
Lung Diseases/et [Etiology]
Lung Diseases/pp [Physiopathology]
Male
Medicine
MLII
MLIII
MPSI
MPSII
MPSVI
Mucopolysaccharidoses/co [Complications]
Mucopolysaccharidoses/mo [Mortality]
Mucopolysaccharidoses/pp [Physiopathology]
pharmacologic interventions
Pyeritz R E
respiratory problems
Respiratory Tract Diseases/et [Etiology]
Respiratory Tract Diseases/pp [Physiopathology]
Respiratory Tract Diseases/ra [Radiography]
Retrospective Studies
Semenza G L
Sleep Apnea Syndromes/et [Etiology]
Spinal Diseases/et [Etiology]
Spinal Diseases/ra [Radiography]
surgical interventions
theophylline
Tonsillectomy
Tracheostomy
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1111/j.1469-8749.1994.tb11850.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1469-8749.1994.tb11850.x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Sleep abnormalities in patients with severe cerebral palsy
Publisher
An entity responsible for making the resource available
Developmental Medicine & Child Neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
Subject
The topic of the resource
Child; Preschool; infant; Human; Electroencephalography; Seizures/co [Complications]; Cerebral Palsy/co [Complications]; Sleep Disorders/et [Etiology]; Sleep Apnea Syndromes/di [Diagnosis]; Sleep Apnea Syndromes/et [Etiology]; Sleep Disorders/di [Diagnosis]
Creator
An entity primarily responsible for making the resource
Kotagal S; Gibbons VP; Stith JA
Description
An account of the resource
The all-night polysomnographic findings of nine patients with spastic quadriparesis (mean age 36.7 months) were analysed retrospectively and compared with those of nine age-matched controls (mean age 37.4 months). The cerebral palsy group had significantly more respiratory disturbances per hour of sleep, with five of nine being diagnosed as having obstructive sleep apnea. They also had fewer changes in body position during the night. Interictal epileptiform discharges averaged 23.3 per cent of the total arousals in the cerebral palsy group. Obstructive apnea, decreased ability to change body position, and interictal epileptiform discharges are prevalent in the sleep of patients with severe cerebral palsy, and contribute towards its disruption.
1994
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1469-8749.1994.tb11850.x" target="_blank" rel="noreferrer">10.1111/j.1469-8749.1994.tb11850.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1994
Backlog
Cerebral Palsy/co [Complications]
Child
Developmental Medicine & Child Neurology
Electroencephalography
Gibbons VP
Human
Infant
Journal Article
Kotagal S
Preschool
Seizures/co [Complications]
Sleep Apnea Syndromes/di [Diagnosis]
Sleep Apnea Syndromes/et [Etiology]
Sleep Disorders/di [Diagnosis]
Sleep Disorders/et [Etiology]
Stith JA