Judging the effectiveness of analgesia for children and adolescents during vaso-occlusive events of sickle cell disease
Child; Female; Humans; Male; Analgesics; Anemia; adolescent; P.H.S.; Research Support; U.S. Gov't; Interviews; Pain/physiopathology; Opioid/therapeutic use; Analgesia/standards; Nalbuphine/therapeutic use; Sickle Cell/complications; Vascular Diseases/etiology/physiopathology/therapy
The effectiveness of analgesia during sickle cell crisis was examined in this descriptive, exploratory study. Pain scores (using the African-American Oucher and the Adolescent Pediatric Pain Tool) and analgesics administered were examined during a 2-hour observation/interview in the hospital while children/adolescents with sickle cell disease (SCD) experienced a vaso-occlusive episode (VOE). A convenience sample of twenty-one 6- to 16-year olds with SCD was included. Evidence indicated that 15 of the 21 children in the sample were in moderate to severe pain during their interviews, indicating that the analgesics did not effectively control their pain. Most participants (17) had received nalbuphine as the primary analgesic by intravenous infusion drip and/or patient-controlled analgesia pump. Many reasons were identified for the inadequate analgesia. The results suggested that the pain of SCD is very complex, requiring continuous adjustment of comfort measures, especially analgesics. More research is needed to examine pain control in children with SCD.
2000
Beyer JE
Journal Of Pain And Symptom Management
2000
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Journal Article
<a href="http://doi.org/10.1016/s0885-3924(99)00134-7" target="_blank" rel="noreferrer">10.1016/s0885-3924(99)00134-7</a>
A comparison of two regimens of patient-controlled analgesia for children with sickle cell disease
Child; Female; Male; Analgesics; Case-Control Studies; Anemia; Comparative Study; retrospective studies; Human; Adolescence; Patient-Controlled; Midwestern United States; Morphine/administration & dosage; Analgesia; Opioid/administration & dosage; Pain/drug therapy/etiology; Sickle Cell/complications
Recently, patient controlled analgesia (PCA) has gained prominence in the treatment of pain for children suffering from vaso-occlusive crisis associated with sickle cell disease. Because there are several different regimens that can be used for PCA, the purpose of this study was to compare and contrast two regimens of patient controlled analgesia (PCA) in terms of safety, efficacy, and cost for the treatment of vaso-occlusive pain associated with sickle cell disease. In this study a retrospective chart review was conducted. The charts of 26 children, hospitalized on 60 different occasions in which PCA was used in the treatment of vaso-occlusive disease were included in the final sample. Patients were grouped according to the type of PCA regimen they received: high dose PCA/low basal infusion (HPCA/LBI) or low dose PCA/high basal infusion (LPCA/HBI). Children in Group 1 (HPCA/LBI) used significantly less morphine during their hospitalization, were hospitalized fewer days, and reported lower pain scores on day 2. There were considerable cost savings due to decreased length of stay, less morphine consumed overall, and fewer days required for rental of the PCA pump.
1998
Trentadue NO; Kachoyeanos MK; Lea G
Journal Of Pediatric Nursing
1998
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Journal Article