1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1007/s10147-013-0521-1" target="_blank" rel="noreferrer">http://doi.org/10.1007/s10147-013-0521-1</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Safe lumbar puncture under analgo-sedation in children with acute lymphoblastic leukemia Publisher An entity responsible for making the resource available International Journal Of Clinical Oncology Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource adolescent; Child; Female; Humans; infant; Male; Pain; Pain Measurement; Deep Sedation; Propofol; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Central Nervous System; Preschool; Injections; Spinal; Spinal Puncture Creator An entity primarily responsible for making the resource Maurizi P; Russo I; Rizzo D; Chiaretti A; Coccia P; Attinà G; Ruggiero A; Riccardi R Description An account of the resource BACKGROUND: Children with acute lymphoblastic leukemia (ALL) undergo multiple lumbar punctures (LPs) during their course of treatment for diagnostic and therapeutic purposes. LP is a stressful and painful procedure, affecting the quality of life of these children. Procedural analgo-sedation might improve the child's comfort and prevent the child's movements, reducing the risk of traumatic lumbar puncture with blasts (TLP+), mainly at diagnosis, when higher numbers of blast cells are circulating in the peripheral blood. The aim of this study was to evaluate the safety and efficacy of procedural analgo-sedation in children with ALL. METHODS: From September 2006 to November 2008, we performed a total of 252 lumbar punctures under deep sedation with propofol and ketamine in 25 children with ALL treated at our division. During the procedures, vital parameters were monitored and side effects were recorded. The efficacy of deep sedation was evaluated using Ramsay and Children's Hospital Eastern Ontario Pain scales. Cerebrospinal fluid was collected for chemical and cytological examinations. RESULTS: In all patients a satisfactory sedation and analgesia were achieved. The evaluation of vital parameters did not show any significant variation compared to baseline values. No side effects were recorded. Only 3 (1.2 %) of 252 lumbar punctures resulted in traumatic effects. CONCLUSION: To strongly improve comfort and quality of life of children with ALL and reduce the risk of TLP+ mainly at diagnosis, we recommend performing the lumbar punctures under analgo-sedation because it is a safe and effective procedure. 2014-02 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1007/s10147-013-0521-1" target="_blank" rel="noreferrer">10.1007/s10147-013-0521-1</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 2014 Adolescent Attinà G Backlog Central Nervous System Chiaretti A Child Coccia P Deep Sedation Female Humans Infant Injections International Journal Of Clinical Oncology Journal Article Male Maurizi P Pain Pain Measurement Precursor Cell Lymphoblastic Leukemia-Lymphoma Preschool Propofol Riccardi R Rizzo D Ruggiero A Russo I Spinal Spinal Puncture