1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1097/01.inf.0000126273.27123.33" target="_blank" rel="noreferrer">http://doi.org/10.1097/01.inf.0000126273.27123.33</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Driscoll Children's Hospital respiratory syncytial virus database: risk factors, treatment and hospital course in 3308 infants and young children, 1991 to 2002 Publisher An entity responsible for making the resource available The Pediatric Infectious Disease Journal Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource Hospitalization; Humans; infant; Intensive Care Units; Pediatrics; Length of Stay; Severity of Illness Index; Risk Factors; Medical Records; infant; Newborn; Premature; Human; Databases; Factual; Mechanical; Ventilators; Antiviral Agents/therapeutic use; Respiratory Syncytial Virus; Respiratory Syncytial Virus Infections/drug therapy/physiopathology/virology; Respiratory Tract Infections/drug therapy/physiopathology/virology; Ribavirin/therapeutic use Creator An entity primarily responsible for making the resource Purcell K; Fergie J Description An account of the resource BACKGROUND: Treatment of respiratory syncytial virus (RSV) lower respiratory tract infection has historically been one of the most frequent reasons for admission to Driscoll Children's Hospital. OBJECTIVE: The objective of this study was to examine the relationship of risk factors for a severe and complicated disease course to the treatment and hospital length of stay. METHODS: Subjects were identified through a retrospective review of the medical records of all patients discharged with a diagnosis of RSV lower respiratory tract infection during 9 of the 11 RSV seasons between July 1, 1991 and June 30, 2002. The RSV seasons from 1991-1992 to 1994-1995 were compared with the RSV seasons from 1995-1996 to 2001-2002 with regard to treatment and hospital course. RESULTS: There were a total of 3308 admissions. Compared with patients with no risk factors, higher percentages of patients with age <6 weeks, history of prematurity, congenital heart disease and neurologic disease were admitted to the pediatric intensive care unit (PICU) and required mechanical ventilation (P < 0.001). Also the hospital length of stay was longer for patients with each of these individual risk factors (P < 0.001). The hospital length of stay and the percentages of patients admitted to the PICU and requiring on mechanical ventilation increased as the number of risk factors increased from zero to 3 or more (P < 0.001). Of patients with 3 or more risk factors, the average hospital length of stay was 13.5 days; 67% were admitted to the PICU, and 47% required mechanical ventilation. Ribavirin use decreased in patients with each of the individual risk factors (P < 0.001) as well as in patients with one or more risk factors (P < 0.001). At the same time the PICU admission rate increased from 6.1% to 11.2% (P < 0.001). CONCLUSIONS: Patients with three or more risk factors were at very high risk for having a severe or complicated disease course associated with admission to the PICU, placement on mechanical ventilation and a longer hospital length of stay. 2004 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1097/01.inf.0000126273.27123.33" target="_blank" rel="noreferrer">10.1097/01.inf.0000126273.27123.33</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 2004 Antiviral Agents/therapeutic use Backlog Databases Factual Fergie J Hospitalization Human Humans Infant Intensive Care Units Journal Article Length Of Stay Mechanical Medical Records Newborn Pediatrics Premature Purcell K Respiratory Syncytial Virus Respiratory Syncytial Virus Infections/drug therapy/physiopathology/virology Respiratory Tract Infections/drug therapy/physiopathology/virology Ribavirin/therapeutic use Risk Factors Severity Of Illness Index The Pediatric Infectious Disease Journal Ventilators