1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1007/s00520-003-0530-0" target="_blank" rel="noreferrer">http://doi.org/10.1007/s00520-003-0530-0</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Oral morphine and respiratory function amongst hospice inpatients with advanced cancer
Publisher
An entity responsible for making the resource available
Supportive Care In Cancer : Official Journal Of The Multinational Association Of Supportive Care In Cancer
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
Subject
The topic of the resource
Female; Humans; Male; Analgesics; Aged; Middle Aged; Drug Monitoring; Health Services Research; Inpatients; Administration; Oral; Pain/drug therapy/etiology; Respiratory Function Tests; hospice care; Morphine/administration & dosage/adverse effects; Neoplasms/classification/complications/physiopathology; Opioid/administration & dosage/adverse effects; Respiratory Insufficiency/chemically induced/diagnosis
Creator
An entity primarily responsible for making the resource
Walsh TD; Rivera NI; Kaiko R
Description
An account of the resource
BACKGROUND: Respiratory depression is the opioid adverse effect feared most by physicians. This may hinder adequate dosing in cancer pain. The study was conducted to examine the respiratory function of patients with advanced cancer receiving significant doses (>100 mg/24 h) of oral morphine. PATIENTS AND METHODS: Consecutive pain-free hospice inpatients with advanced cancer receiving high-dose immediate-release oral morphine were evaluated. A single assessment of respiratory rate (RR), arterial blood gas (ABG), and peak flow rate (PFR) was made at assumed morphine steady state. Venous blood was drawn for a trough morphine plasma level. RESULTS: Of 31 patients who consented to examination, 20 completed the study assessment; 12 had chronic bronchitis. The median morphine dose was 30 mg 4-hourly (range 20 to 90 mg). Only one patient had evidence of ventilatory impairment. CONCLUSIONS: Morphine does not commonly cause chronic ventilatory impairment when given in this way in this population even in the presence of pre-existing or concurrent respiratory disease. Oral morphine given repeatedly in individualized dosage is a safe and efficacious analgesic in the majority of those with advanced cancer.
2003
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s00520-003-0530-0" target="_blank" rel="noreferrer">10.1007/s00520-003-0530-0</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2003
Administration
Aged
Analgesics
Backlog
Drug Monitoring
Female
Health Services Research
Hospice Care
Humans
Inpatients
Journal Article
Kaiko R
Male
Middle Aged
Morphine/administration & dosage/adverse effects
Neoplasms/classification/complications/physiopathology
Opioid/administration & dosage/adverse effects
Oral
Pain/drug therapy/etiology
Respiratory Function Tests
Respiratory Insufficiency/chemically induced/diagnosis
Rivera NI
Supportive Care In Cancer : Official Journal Of The Multinational Association Of Supportive Care In Cancer
Walsh TD