1
40
9
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Dublin Core
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Title
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2021 Special Edition 2 - Oncology
Text
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Citation List Month
2021 Special Edition - Oncology
URL Address
<a href="http://doi.org/10.1186/s12887-021-02841-7" target="_blank" rel="noreferrer noopener"> http://doi.org/10.1186/s12887-021-02841-7</a>
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Advance Care Planning For Adolescents with Cancer and Their Parents: Study Protocol of the Boost Pacp Multi-Centre Randomised Controlled Trial and Process Evaluation
Publisher
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BMC Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2021
Subject
The topic of the resource
Child; Adolescent; Humans; Terminal Care; Surveys and Questionnaires; Parents; Communication; Advance Care Planning; Randomized Controlled Trials as Topic; Multicenter Studies as Topic; Advance care planning; Neoplasms/therapy; Adolescent; Multi-Centre randomised controlled trial; Paediatric oncology; Paediatric palliative care; Parent-adolescent communication
Creator
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van Driessche A; De Vleminck A; Gilissen J; Kars MC; van der Werff TBJ; Deliens L; Cohen J; Beernaert K
Description
An account of the resource
BACKGROUND: Research has highlighted the need for evidence-based interventions to improve paediatric advance care planning (pACP) in adolescents with cancer. Although adolescents express the desire and ability to share their values, beliefs and preferences for treatment, there is a lack of structured multicomponent interventions to improve parent-adolescent communication on different ACP themes including those not limited to end-of-life care. The aim of this study is to evaluate the effectiveness and implementation, context and mechanisms of impact of a novel ACP program in paediatric oncology. METHODS: We will conduct a multi-centre parallel-group randomised controlled superiority trial with embedded mixed-methods process evaluation in Flanders, Belgium. Adolescents aged 10-18 who have cancer, and their parent(s) will be recruited via all four university hospitals in Flanders, Belgium, and support groups. Families will be randomised to receive care as usual or the multicomponent BOOST pACP program, consisting of three conversation sessions between an external facilitator and the adolescent and parent(s). The primary endpoint is improved parent-adolescent communication from the perspective of the adolescent. Secondary endpoints are adolescents' and parents' attitudes, self-efficacy, intention and behaviour regarding talking about ACP themes with each other, parents' perspective of shared decision making in the last clinical encounter, and the paediatric oncologist's intention and behaviour regarding talking about ACP themes with the family. Measurements will be performed at baseline, at 3 months and at 7 months using structured self-reported questionnaires. We will perform a process evaluation in the intervention group, with measurement throughout and post-intervention, using structured diaries filled out by the facilitators, interviews with facilitators, interviews with involved paediatric oncology teams, and audio-recordings of the BOOST pACP conversations. DISCUSSION: The BOOST pACP program has been developed to stimulate conversations on ACP themes between parent(s) and the adolescents, simultaneously lowering the threshold to discuss similar themes with healthcare professionals, initiating a process of normalization and integration of ACP in standard care. This combined outcome and process evaluation aims to contribute to building the necessary evidence to improve ACP in paediatric oncology. TRIAL REGISTRATION: The study is registered at ISRCTN, ISRCTN33228289 . Registration date: January 22, 2021.
Identifier
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<a href="http://doi.org/10.1186/s12887-021-02841-7" target="_blank" rel="noreferrer noopener">10.1186/s12887-021-02841-7</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2021
2021 Special Edition - Oncology
Adolescent
Advance Care Planning
Beernaert K
Bmc Pediatrics
Child
Cohen J
Communication
De Vleminck A
Deliens L
Gilissen J
Humans
Kars MC
Multi-Centre randomised controlled trial
Multicenter Studies as Topic
Neoplasms/therapy
Paediatric oncology
paediatric palliative care
Parent-adolescent communication
Parents
Randomized Controlled Trials as Topic
Surveys And Questionnaires
Terminal Care
van der Werff TBJ
van Driessche A
-
Dublin Core
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Title
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January 2021 List
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
January 2021 List
URL Address
<a href="http://doi.org/10.1002/14651858.CD002271.pub3" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/14651858.CD002271.pub3</a>
Dublin Core
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Title
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Continuous positive airway pressure (CPAP) for respiratory distress in preterm infants
Publisher
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Cochrane Database of Systematic Reviews
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
Subject
The topic of the resource
Humans; Infant Newborn; Treatment Failure; Infant Premature; Randomized Controlled Trials as Topic; Selection Bias; Infant Low Birth Weight; Pneumothorax/etiology; Outcome Assessment Health Care; Bronchopulmonary Dysplasia/etiology; Continuous Positive Airway Pressure/adverse effects/methods; Intermittent Positive-Pressure Ventilation/adverse effects; Pulmonary Surfactants/therapeutic use; Respiratory Insufficiency/prevention & control; Respiratory Distress Syndrome Newborn/mortality/therapy
Creator
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Ho JJ; Subramaniam P; Davis PG
Description
An account of the resource
BACKGROUND: Respiratory distress, particularly respiratory distress syndrome (RDS), is the single most important cause of morbidity and mortality in preterm infants. In infants with progressive respiratory insufficiency, intermittent positive pressure ventilation (IPPV) with surfactant has been the usual treatment, but it is invasive, potentially resulting in airway and lung injury. Continuous positive airway pressure (CPAP) has been used for the prevention and treatment of respiratory distress, as well as for the prevention of apnoea, and in weaning from IPPV. Its use in the treatment of RDS might reduce the need for IPPV and its sequelae. OBJECTIVES: To determine the effect of continuous distending pressure in the form of CPAP on the need for IPPV and associated morbidity in spontaneously breathing preterm infants with respiratory distress. SEARCH METHODS: We used the standard strategy of Cochrane Neonatal to search CENTRAL (2020, Issue 6); Ovid MEDLINE and Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Daily and Versions; and CINAHL on 30 June 2020. We also searched clinical trials databases and the reference lists of retrieved articles for randomised controlled trials and quasi-randomised trials. SELECTION CRITERIA: All randomised or quasi-randomised trials of preterm infants with respiratory distress were eligible. Interventions were CPAP by mask, nasal prong, nasopharyngeal tube or endotracheal tube, compared with spontaneous breathing with supplemental oxygen as necessary. DATA COLLECTION AND ANALYSIS: We used standard methods of Cochrane and its Neonatal Review Group, including independent assessment of risk of bias and extraction of data by two review authors. We used the GRADE approach to assess the certainty of evidence. Subgroup analyses were planned on the basis of birth weight (greater than or less than 1000 g or 1500 g), gestational age (groups divided at about 28 weeks and 32 weeks), timing of application (early versus late in the course of respiratory distress), pressure applied (high versus low) and trial setting (tertiary compared with non-tertiary hospitals; high income compared with low income) MAIN RESULTS: We included five studies involving 322 infants; two studies used face mask CPAP, two studies used nasal CPAP and one study used endotracheal CPAP and continuing negative pressure for a small number of less ill babies. For this update, we included one new trial. CPAP was associated with lower risk of treatment failure (death or use of assisted ventilation) (typical risk ratio (RR) 0.64, 95% confidence interval (CI) 0.50 to 0.82; typical risk difference (RD) -0.19, 95% CI -0.28 to -0.09; number needed to treat for an additional beneficial outcome (NNTB) 6, 95% CI 4 to 11; I(2) = 50%; 5 studies, 322 infants; very low-certainty evidence), lower use of ventilatory assistance (typical RR 0.72, 95% CI 0.54 to 0.96; typical RD -0.13, 95% CI -0.25 to -0.02; NNTB 8, 95% CI 4 to 50; I(2) = 55%; very low-certainty evidence) and lower overall mortality (typical RR 0.53, 95% CI 0.34 to 0.83; typical RD -0.11, 95% CI -0.18 to -0.04; NNTB 9, 95% CI 2 to 13; I(2) = 0%; 5 studies, 322 infants; moderate-certainty evidence). CPAP was associated with increased risk of pneumothorax (typical RR 2.48, 95% CI 1.16 to 5.30; typical RD 0.09, 95% CI 0.02 to 0.16; number needed to treat for an additional harmful outcome (NNTH) 11, 95% CI 7 to 50; I(2) = 0%; 4 studies, 274 infants; low-certainty evidence). There was no evidence of a difference in bronchopulmonary dysplasia, defined as oxygen dependency at 28 days (RR 1.04, 95% CI 0.35 to 3.13; I(2) = 0%; 2 studies, 209 infants; very low-certainty evidence). The trials did not report use of surfactant, intraventricular haemorrhage, retinopathy of prematurity, necrotising enterocolitis and neurodevelopment outcomes in childhood. AUTHORS' CONCLUSIONS: In preterm infants with respiratory distress, the application of CPAP is associated with reduced respiratory failure, use of mechanical ventilation and mortality and an increased rate of pneumothorax compared to spontaneous breathing with supplemental oxygen as necessary. Three out of five of these trials were conducted in the 1970s. Therefore, the applicability of these results to current practice is unclear. Further studies in resource-poor settings should be considered and research to determine the most appropriate pressure level needs to be considered.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/14651858.CD002271.pub3" target="_blank" rel="noreferrer noopener">10.1002/14651858.CD002271.pub3</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2020
Bronchopulmonary Dysplasia/etiology
Cochrane Database of Systematic Reviews
Continuous Positive Airway Pressure/adverse effects/methods
Davis PG
Ho JJ
Humans
Infant Low Birth Weight
Infant Newborn
Infant Premature
Intermittent Positive-Pressure Ventilation/adverse effects
January 2021 List
Outcome Assessment Health Care
Pneumothorax/etiology
Pulmonary Surfactants/therapeutic use
Randomized Controlled Trials as Topic
Respiratory Distress Syndrome Newborn/mortality/therapy
Respiratory Insufficiency/prevention & control
Selection Bias
Subramaniam P
Treatment Failure
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1093/rheumatology/ken110" target="_blank" rel="noreferrer">http://doi.org/10.1093/rheumatology/ken110</a>
Dublin Core
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Title
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Is there any evidence to support the use of anti-depressants in painful rheumatological conditions? Systematic review of pharmacological and clinical studies
Publisher
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Rheumatology
Date
A point or period of time associated with an event in the lifecycle of the resource
2008
Subject
The topic of the resource
Humans; Evidence-Based Medicine; Randomized Controlled Trials as Topic; Chronic disease; Pain/drug therapy/etiology; Fibromyalgia/drug therapy; Antidepressive Agents/therapeutic use; Arthritis/complications/drug therapy; Low Back Pain/drug therapy; Rheumatic Diseases/complications/drug therapy
Creator
An entity primarily responsible for making the resource
Perrot S; Javier RM; Marty M; Le Jeunne C; Laroche F; CEDR (Cercle d'Etude de la Douleur en Rhumatologie France) Pain Study Section French Rheumatological Society
Description
An account of the resource
The aim of this study was to review the evidence supporting the use of anti-depressants in painful rheumatological conditions. A systematic review of papers published between 1966 and 2007, in five European languages, on anti-depressants in rheumatological conditions was performed. Papers were scored using Jadad method and analgesic ES was calculated. We selected 78 clinical studies and 12 meta-analyses, from 140 papers. The strongest evidence of an analgesic effect of anti-depressants has been obtained for fibromyalgia. A weak analgesic effect is observed for chronic low back pain, with an efficacy level close to that of analgesics. In RA and AS, there is no analgesic effect of anti-depressants, but these drugs may help to manage fatigue and sleep disorders. There is no clear evidence of an analgesic effect inOA, but studies have poor methodological quality. Analgesic effects of anti-depressants are independent of their anti-depressant effects. Tricyclic anti-depressants (TCAs), even at low doses, have analgesic effects equivalent to those of serotonin and noradrenalin reuptake inhibitors (SNRIs), but are less well tolerated. Selective serotonin reuptake inhibitors (SSRIs) have modest analgesic effects, but higher doses are required to achieve analgesia. Anti-depressant drugs, particularly TCAs and SNRIs, have analgesic effects in chronic rheumatic painful states in which analgesics and NSAIDs are not very efficient, such as fibromyalgia and chronic low back pain. In inflammatory rheumatic diseases, anti-depressants may be useful for managing fatigue and sleep disorders. Further studies are required to compare anti-depressants with other analgesics in the management of chronic painful rheumatological conditions.
2008
Identifier
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<a href="http://doi.org/10.1093/rheumatology/ken110" target="_blank" rel="noreferrer">10.1093/rheumatology/ken110</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2008
Antidepressive Agents/therapeutic use
Arthritis/complications/drug therapy
Backlog
CEDR (Cercle d'Etude de la Douleur en Rhumatologie France) Pain Study Section French Rheumatological Society
Chronic Disease
Evidence-based Medicine
Fibromyalgia/drug therapy
Humans
Javier RM
Journal Article
Laroche F
Le Jeunne C
Low Back Pain/drug therapy
Marty M
Pain/drug therapy/etiology
Perrot S
Randomized Controlled Trials as Topic
Rheumatic Diseases/complications/drug therapy
Rheumatology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1136/adc.2009.160994" target="_blank" rel="noreferrer">http://doi.org/10.1136/adc.2009.160994</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Role of systemic steroids in acute preschool wheeze
Publisher
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Archives Of Disease In Childhood
Date
A point or period of time associated with an event in the lifecycle of the resource
2010
Subject
The topic of the resource
Child; Humans; Acute Disease; Randomized Controlled Trials as Topic; Emergency Service; Preschool; infant; Hospital; Glucocorticoids/pharmacology; Respiratory Sounds/drug effects
Creator
An entity primarily responsible for making the resource
Grigg J
Identifier
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<a href="http://doi.org/10.1136/adc.2009.160994" target="_blank" rel="noreferrer">10.1136/adc.2009.160994</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2010
2010
Acute Disease
Archives of Disease in Childhood
Backlog
Child
Emergency Service
Glucocorticoids/pharmacology
Grigg J
Hospital
Humans
Infant
Journal Article
Preschool
Randomized Controlled Trials as Topic
Respiratory Sounds/drug effects
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1186/1471-2288-10-1" target="_blank" rel="noreferrer">http://doi.org/10.1186/1471-2288-10-1</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
A tutorial on pilot studies: the what, why and how
Publisher
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Bmc Medical Research Methodology
Date
A point or period of time associated with an event in the lifecycle of the resource
2010
Subject
The topic of the resource
Humans; Pilot Projects; Randomized Controlled Trials as Topic; Clinical Trials; Research Design/standards; Phase III as Topic/methods
Creator
An entity primarily responsible for making the resource
Thabane L; Ma J; Chu R; Cheng J; Ismaila A; Rios LP; Robson R; Thabane M; Giangregorio L; Goldsmith CH
Description
An account of the resource
Pilot studies for phase III trials - which are comparative randomized trials designed to provide preliminary evidence on the clinical efficacy of a drug or intervention - are routinely performed in many clinical areas. Also commonly know as "feasibility" or "vanguard" studies, they are designed to assess the safety of treatment or interventions; to assess recruitment potential; to assess the feasibility of international collaboration or coordination for multicentre trials; to increase clinical experience with the study medication or intervention for the phase III trials. They are the best way to assess feasibility of a large, expensive full-scale study, and in fact are an almost essential pre-requisite. Conducting a pilot prior to the main study can enhance the likelihood of success of the main study and potentially help to avoid doomed main studies. The objective of this paper is to provide a detailed examination of the key aspects of pilot studies for phase III trials including: 1) the general reasons for conducting a pilot study; 2) the relationships between pilot studies, proof-of-concept studies, and adaptive designs; 3) the challenges of and misconceptions about pilot studies; 4) the criteria for evaluating the success of a pilot study; 5) frequently asked questions about pilot studies; 7) some ethical aspects related to pilot studies; and 8) some suggestions on how to report the results of pilot investigations using the CONSORT format.
2010
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1186/1471-2288-10-1" target="_blank" rel="noreferrer">10.1186/1471-2288-10-1</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2010
Backlog
Bmc Medical Research Methodology
Cheng J
Chu R
Clinical Trials
Giangregorio L
Goldsmith CH
Humans
Ismaila A
Journal Article
Ma J
Phase III as Topic/methods
Pilot Projects
Randomized Controlled Trials as Topic
Research Design/standards
Rios LP
Robson R
Thabane L
Thabane M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1503/cmaj.082007" target="_blank" rel="noreferrer">http://doi.org/10.1503/cmaj.082007</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
What kind of randomized trials do we need?
Publisher
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Canadian Medical Association Journal
Date
A point or period of time associated with an event in the lifecycle of the resource
2009
Subject
The topic of the resource
Humans; United States; Research Design; United States Food and Drug Administration; Randomized Controlled Trials as Topic
Creator
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Zwarenstein M; Treweek S
Identifier
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<a href="http://doi.org/10.1503/cmaj.082007" target="_blank" rel="noreferrer">10.1503/cmaj.082007</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2009
2009
Backlog
Canadian Medical Association Journal
Humans
Journal Article
Randomized Controlled Trials as Topic
Research Design
Treweek S
United States
United States Food and Drug Administration
Zwarenstein M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1007/s11920-005-0004-9" target="_blank" rel="noreferrer">http://doi.org/10.1007/s11920-005-0004-9</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Treatment of mania in children and adolescents
Publisher
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Current Psychiatry Reports
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
Subject
The topic of the resource
Child; Humans; Randomized Controlled Trials as Topic; adolescent; Antimanic Agents/adverse effects/therapeutic use; Antipsychotic Agents/adverse effects/therapeutic use; Bipolar Disorder/diagnosis/drug therapy/psychology; Carbamazepine/adverse effects/therapeutic use; Lithium Compounds/adverse effects/therapeutic use; Valproic Acid/adverse effects/therapeutic use
Creator
An entity primarily responsible for making the resource
Sheikh R; Kang J; Weller R; Weller EB
Description
An account of the resource
Bipolar disorder (BPD) is a severe and complex illness that seriously disrupts the lives of those afflicted. Increased rates of suicide attempts and completions, poorer academic performances, disturbed interpersonal relationships, increased rates of substance abuse, legal difficulties, and multiple hospitalizations all have been associated with BPD. At least 1% of children and adolescents have this disorder. This commentary is designed to review and summarize the recent literature on the treatment of manic and/or hypomanic phases of BPD in children and adolescents.
2005
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s11920-005-0004-9" target="_blank" rel="noreferrer">10.1007/s11920-005-0004-9</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2005
Adolescent
Antimanic Agents/adverse effects/therapeutic use
Antipsychotic Agents/adverse effects/therapeutic use
Backlog
Bipolar Disorder/diagnosis/drug therapy/psychology
Carbamazepine/adverse effects/therapeutic use
Child
Current Psychiatry Reports
Humans
Journal Article
Kang J
Lithium Compounds/adverse effects/therapeutic use
Randomized Controlled Trials as Topic
Sheikh R
Valproic Acid/adverse effects/therapeutic use
Weller EB
Weller R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1186/1471-2288-12-80" target="_blank" rel="noreferrer">http://doi.org/10.1186/1471-2288-12-80</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The quality of the evidence base for clinical pathway effectiveness: room for improvement in the design of evaluation trials.
Publisher
An entity responsible for making the resource available
Bmc Medical Research Methodology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
Subject
The topic of the resource
Humans; Length of Stay; Risk Assessment; Clinical Trials as Topic; Reproducibility of Results; Randomized Controlled Trials as Topic; Bias (Epidemiology); Meta-Analysis as Topic; Evidence-Based Medicine; Selection Bias; Critical Pathways/st [Standards]; Guidelines as Topic; Outcome and Process Assessment (Health Care); Research Design/st [Standards]
Creator
An entity primarily responsible for making the resource
Kinsman L; James E; Machotta A; Steyerberg EW
Description
An account of the resource
BACKGROUND: The purpose of this article is to report on the quality of the existing evidence base regarding the effectiveness of clinical pathway (CPW) research in the hospital setting. The analysis is based on a recently published Cochrane review of the effectiveness of CPWs., METHODS: An integral component of the review process was a rigorous appraisal of the methodological quality of published CPW evaluations. This allowed the identification of strengths and limitations of the evidence base for CPW effectiveness. We followed the validated Cochrane Effective Practice and Organisation of Care Group (EPOC) criteria for randomized and non-randomized clinical pathway evaluations. In addition, we tested the hypotheses that simple pre-post studies tend to overestimate CPW effects reported., RESULTS: Out of the 260 primary studies meeting CPW content criteria, only 27 studies met the EPOC study design criteria, with the majority of CPW studies (more than 70%) excluded from the review on the basis that they were simple pre-post evaluations, mostly comparing two or more annual patient cohorts. Methodologically poor study designs are often used to evaluate CPWs and this compromises the quality of the existing evidence base., CONCLUSIONS: Cochrane EPOC methodological criteria, including the selection of rigorous study designs along with detailed descriptions of CPW development and implementation processes, are recommended for quantitative evaluations to improve the evidence base for the use of CPWs in hospitals.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1186/1471-2288-12-80" target="_blank" rel="noreferrer">10.1186/1471-2288-12-80</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2012
Backlog
Bias (Epidemiology)
Bmc Medical Research Methodology
Clinical Trials as Topic
Critical Pathways/st [Standards]
Evidence-based Medicine
Guidelines As Topic
Humans
James E
Journal Article
Kinsman L
Length Of Stay
Machotta A
Meta-Analysis as Topic
Outcome And Process Assessment (health Care)
Randomized Controlled Trials as Topic
Reproducibility of Results
Research Design/st [Standards]
Risk Assessment
Selection Bias
Steyerberg EW
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1186/1748-5908-7-47" target="_blank" rel="noreferrer">http://doi.org/10.1186/1748-5908-7-47</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The European quality of care pathways (EQCP) study on the impact of care pathways on interprofessional teamwork in an acute hospital setting: study protocol: for a cluster randomised controlled trial and evaluation of implementation processes.
Publisher
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Implementation Science
Date
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2012
Subject
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Humans; Comorbidity; Europe; Pulmonary Disease; Process Assessment (Health Care); Critical Pathways; Research Design; Interprofessional Relations; Randomized Controlled Trials as Topic; Chronic Obstructive/ep [Epidemiology]; Chronic Obstructive/th [Therapy]; Femoral Fractures/ep [Epidemiology]; Femoral Fractures/th [Therapy]
Creator
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Euwema M; Lodewijckx C; Panella M; Sermeus W; Vanhaecht K
Description
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BACKGROUND: Although care pathways are often said to promote teamwork, high-level evidence that supports this statement is lacking. Furthermore, knowledge on conditions and facilitators for successful pathway implementation is scarce. The objective of the European Quality of Care Pathway (EQCP) study is therefore to study the impact of care pathways on interprofessional teamwork and to build up understanding on the implementation process., METHODS/DESIGN: An international post-test-only cluster Randomised Controlled Trial (cRCT), combined with process evaluations, will be performed in Belgium, Ireland, Italy, and Portugal. Teams caring for proximal femur fracture (PFF) patients and patients hospitalized with an exacerbation of chronic obstructive pulmonary disease (COPD) will be randomised into an intervention and control group. The intervention group will implement a care pathway for PFF or COPD containing three active components: a formative evaluation of the actual teams' performance, a set of evidence-based key interventions, and a training in care pathway-development. The control group will provide usual care. A set of team input, process and output indicators will be used as effect measures. The main outcome indicator will be relational coordination. Next to these, process measures during and after pathway development will be used to evaluate the implementation processes. In total, 132 teams have agreed to participate, of which 68 were randomly assigned to the intervention group and 64 to the control group. Based on power analysis, a sample of 475 team members per arm is required. To analyze results, multilevel analysis will be performed., DISCUSSION: Results from our study will enhance understanding on the active components of care pathways. Through this, preferred implementation strategies can be defined.
Identifier
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<a href="http://doi.org/10.1186/1748-5908-7-47" target="_blank" rel="noreferrer">10.1186/1748-5908-7-47</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2012
Backlog
Chronic Obstructive/ep [Epidemiology]
Chronic Obstructive/th [Therapy]
Comorbidity
Critical Pathways
Europe
Euwema M
Femoral Fractures/ep [Epidemiology]
Femoral Fractures/th [Therapy]
Humans
Implementation Science
Interprofessional Relations
Journal Article
Lodewijckx C
Panella M
Process Assessment (Health Care)
Pulmonary Disease
Randomized Controlled Trials as Topic
Research Design
Sermeus W
Vanhaecht K