1
40
3
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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URL Address
<a href="http://doi.org/10.1038/nrclinonc.2011.95" target="_blank" rel="noreferrer">http://doi.org/10.1038/nrclinonc.2011.95</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Challenging issues in pediatric oncology
Publisher
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Nature Reviews Clinical Oncology
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
Creator
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Pui CH; Gajjar A; Kane JR; Qaddoumi IA; Pappo AS; Medscape
Description
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Improvements in protocol-driven clinical trials and supportive care for children and adolescents with cancer have reduced mortality rates by more than 50% over the past three decades. Overall, the 5-year survival rate for patients with pediatric cancer has increased to approximately 80%. Recognition of the biological heterogeneity within specific subtypes of cancer, the discovery of genetic lesions that drive malignant transformation and cancer progression, and improved understanding of the basis of drug resistance will undoubtedly catalyze further advances in risk-directed treatments and the development of targeted therapies, boosting the cure rates further. Emerging new treatments include novel formulations of existing chemotherapeutic agents, monoclonal antibodies against cancer-associated antigens, and molecular therapies that target genetic lesions and their associated signaling pathways. Recent findings that link pharmacogenomic variations with drug exposure, adverse effects, and efficacy should accelerate efforts to develop personalized therapy for individual patients. Finally, palliative care should be included as an essential part of cancer management to prevent and relieve the suffering and to improve the quality of life of patients and their families.
Identifier
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<a href="http://doi.org/10.1038/nrclinonc.2011.95" target="_blank" rel="noreferrer">10.1038/nrclinonc.2011.95</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2011
Backlog
Gajjar A
Journal Article
Kane JR
Medscape
Nature Reviews Clinical Oncology
Pappo AS
Pui CH
Qaddoumi IA
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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URL Address
<a href="http://doi.org/10.1023/b:qure.0000021697.43165.87" target="_blank" rel="noreferrer">http://doi.org/10.1023/b:qure.0000021697.43165.87</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Quality of life as conveyed by pediatric patients with cancer
Publisher
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Quality of Life Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
Subject
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adolescent; U.S. Gov't; PedPal Lit; Non-U.S. Gov't Research Support; psychology Questionnaires Research Support; Adolescent Psychology Cancer Care Facilities Child; Child Psychology Female Humans Interviews Male Neoplasms/physiopathology/; methods Quality of Life/; P.H.S. Self Assessment (Psychology); psychology/therapy Pediatrics Pilot Projects Psychometrics/instrumentation/; Sickness Impact Profile Tennessee; the domain most frequently missing was the meaning of being ill domain. Here we present a new definition of the quality of life of pediatric oncology patients that is based on six domains; this definition may ensure the completeness and sensitivity of these important instruments.
Creator
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Hinds PS; Gattuso JS; Fletcher A; Baker E; Coleman B; Jackson T; Jacobs-Levine A; June D; Rai SN; Lensing S; Pui CH
Identifier
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<a href="http://doi.org/10.1023/b:qure.0000021697.43165.87" target="_blank" rel="noreferrer">10.1023/b:qure.0000021697.43165.87</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2004
2004
Adolescent
Adolescent Psychology Cancer Care Facilities Child
Backlog
Baker E
Child Psychology Female Humans Interviews Male Neoplasms/physiopathology/
Coleman B
Fletcher A
Gattuso JS
Hinds PS
Jackson T
Jacobs-Levine A
Journal Article
June D
Lensing S
methods Quality of Life/
Non-U.S. Gov't Research Support
P.H.S. Self Assessment (Psychology)
PedPal Lit
psychology Questionnaires Research Support
psychology/therapy Pediatrics Pilot Projects Psychometrics/instrumentation/
Pui CH
Quality of Life Research
Rai SN
Sickness Impact Profile Tennessee
the domain most frequently missing was the meaning of being ill domain. Here we present a new definition of the quality of life of pediatric oncology patients that is based on six domains
this definition may ensure the completeness and sensitivity of these important instruments.
U.S. Gov't
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1007/s11136-004-4714-y" target="_blank" rel="noreferrer">http://doi.org/10.1007/s11136-004-4714-y</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Proxy assessment of quality of life in pediatric clinical trials: application of the Health Utilities Index 3
Publisher
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Quality of Life Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
Subject
The topic of the resource
symptoms; U.S. Gov't; PedPal Lit; Extramural Research Support; N.I.H.; Non-U.S. Gov't Research Support; Adolescent ChildClinical Trials Female Health Status Humans Leukemia/drug therapy/physiopathology/psychology MalePediatricsProxy Quality of Life/psychology Research Support; domains specific and sensitive to both disease and treatment; P.H.S.Sickness Impact Profile%X BACKGROUND: With increased cure rates; pediatric oncology protocols increasingly seek to document the impact of treatment on patients' disease; the proxy respondents evaluated the ease of use of the instrument and the data quality. RESULTS: As patients' health status declined
Creator
An entity primarily responsible for making the resource
Cox CL; Lensing S; Rai SN; Hinds P; Burghen E; Pui CH
Identifier
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<a href="http://doi.org/10.1007/s11136-004-4714-y" target="_blank" rel="noreferrer">10.1007/s11136-004-4714-y</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2005
2005
Adolescent ChildClinical Trials Female Health Status Humans Leukemia/drug therapy/physiopathology/psychology MalePediatricsProxy Quality of Life/psychology Research Support
Backlog
Burghen E
Cox CL
domains specific and sensitive to both disease and treatment
Extramural Research Support
Hinds P
Journal Article
Lensing S
N.I.H.
Non-U.S. Gov't Research Support
P.H.S.Sickness Impact Profile%X BACKGROUND: With increased cure rates
pediatric oncology protocols increasingly seek to document the impact of treatment on patients' disease
PedPal Lit
Pui CH
Quality of Life Research
Rai SN
Symptoms
the proxy respondents evaluated the ease of use of the instrument and the data quality. RESULTS: As patients' health status declined
U.S. Gov't