1
40
3
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1186/1471-2288-6-57" target="_blank" rel="noreferrer">http://doi.org/10.1186/1471-2288-6-57</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Dealing with missing data in a multi-question depression scale: a comparison of imputation methods
Publisher
An entity responsible for making the resource available
Bmc Medical Research Methodology
Date
A point or period of time associated with an event in the lifecycle of the resource
2006
Subject
The topic of the resource
Female; Humans; Male; Attitude to Health; Questionnaires; Research Design; Hospitals; Reproducibility of Results; Regression Analysis; Alberta; Teaching; Statistical; Data Interpretation; Psychiatric Status Rating Scales; Self Assessment (Psychology); Surgical Procedures; Depression/classification/diagnosis; Operative/psychology; Outcome Assessment (Health Care)/methods/statistics & numerical data; Preoperative Care; Psychometrics/methods
Creator
An entity primarily responsible for making the resource
Shrive FM; Stuart H; Quan H; Ghali WA
Description
An account of the resource
BACKGROUND: Missing data present a challenge to many research projects. The problem is often pronounced in studies utilizing self-report scales, and literature addressing different strategies for dealing with missing data in such circumstances is scarce. The objective of this study was to compare six different imputation techniques for dealing with missing data in the Zung Self-reported Depression scale (SDS). METHODS: 1580 participants from a surgical outcomes study completed the SDS. The SDS is a 20 question scale that respondents complete by circling a value of 1 to 4 for each question. The sum of the responses is calculated and respondents are classified as exhibiting depressive symptoms when their total score is over 40. Missing values were simulated by randomly selecting questions whose values were then deleted (a missing completely at random simulation). Additionally, a missing at random and missing not at random simulation were completed. Six imputation methods were then considered; 1) multiple imputation, 2) single regression, 3) individual mean, 4) overall mean, 5) participant's preceding response, and 6) random selection of a value from 1 to 4. For each method, the imputed mean SDS score and standard deviation were compared to the population statistics. The Spearman correlation coefficient, percent misclassified and the Kappa statistic were also calculated. RESULTS: When 10% of values are missing, all the imputation methods except random selection produce Kappa statistics greater than 0.80 indicating 'near perfect' agreement. MI produces the most valid imputed values with a high Kappa statistic (0.89), although both single regression and individual mean imputation also produced favorable results. As the percent of missing information increased to 30%, or when unbalanced missing data were introduced, MI maintained a high Kappa statistic. The individual mean and single regression method produced Kappas in the 'substantial agreement' range (0.76 and 0.74 respectively). CONCLUSION: Multiple imputation is the most accurate method for dealing with missing data in most of the missind data scenarios we assessed for the SDS. Imputing the individual's mean is also an appropriate and simple method for dealing with missing data that may be more interpretable to the majority of medical readers. Researchers should consider conducting methodological assessments such as this one when confronted with missing data. The optimal method should balance validity, ease of interpretability for readers, and analysis expertise of the research team.
2006
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1186/1471-2288-6-57" target="_blank" rel="noreferrer">10.1186/1471-2288-6-57</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2006
Alberta
Attitude To Health
Backlog
Bmc Medical Research Methodology
Data Interpretation
Depression/classification/diagnosis
Female
Ghali WA
Hospitals
Humans
Journal Article
Male
Operative/psychology
Outcome Assessment (Health Care)/methods/statistics & numerical data
Preoperative Care
Psychiatric Status Rating Scales
Psychometrics/methods
Quan H
Questionnaires
Regression Analysis
Reproducibility of Results
Research Design
Self Assessment (Psychology)
Shrive FM
statistical
Stuart H
Surgical Procedures
Teaching
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1097/PEP.0b013e3182351f04" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/PEP.0b013e3182351f04</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Validation of the Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP INTEND)
Publisher
An entity responsible for making the resource available
Pediatric Physical Therapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
Subject
The topic of the resource
infant; Pediatrics; Rehabilitation; validity; outcome assessment; child; female; male; disease severity; (health care); atrophies of childhood/diagnosis; child development/physiology; childhood/physiopathology; disability evaluation; humans; motor skills/physiology; natural-history; physical therapy/methods; preschool; psychometrics/methods; severity of illness index; sma; smn2 copy number; spinal muscular; spinal muscular atrophies of; spinal muscular-atrophy; tone and motor problems; SMA1; tool development; scale development; CHOP INTEND
Creator
An entity primarily responsible for making the resource
Glanzman A M; McDermott M P; Montes J; Martens W B; Flickinger J; Riley S; Quigley J; Dunaway S; O'Hagen J; Deng L Y; Chung W K; Tawil R; Darras B T; Yang M; Sproule D; De Vivo D C; Kaufmann P; Finkel R S; Pediatric Neuromuscular Clinical Research; Muscle Study Group
Description
An account of the resource
Purpose: Preliminary validation of the Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP INTEND) for motor skill assessment in spinal muscular atrophy type I. Methods: A total of 27 subjects 3 to 260 months old (mean = 49, SD = 69) with spinal muscular atrophy-I were evaluated with the CHOP INTEND. Subjects were evaluated as part of a multicenter natural history study. Results: CHOP INTEND scores and age were significantly correlated (r = -0.51, P = .007; 2 survival of the motor neuron [SMN] 2 gene copies, n = 16, r = -0.60, 3 SMN2 gene copies, n = 9, r = -0.83). Respiratory support and CHOP INTEND scores were correlated (r = -0.74, P <.0001, n = 26). The CHOP INTEND and age regression in patients with 2 copies versus 3 copies of SMN2 approached significance (P = .0711, n = 25). Subjects who required respiratory support scored significantly lower (mean = 15.5, SD = 10.2 vs mean = 31.2, SD = 4.2, P <.0001, n = 27). Correlation with motor unit number estimation and combined motor unit activation were not significant. Conclusion: The CHOP INTEND reflects measures of disease severity and supports continued exploration of the CHOP INTEND. (Pediatr Phys Ther 2011; 23: 322-326)
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/PEP.0b013e3182351f04" target="_blank" rel="noreferrer noopener">10.1097/PEP.0b013e3182351f04</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
(health care)
2011
atrophies of childhood/diagnosis
Child
Child Development/physiology
childhood/physiopathology
CHOP INTEND
Chung W K
Darras B T
De Vivo D C
Deng L Y
Disability Evaluation
Disease Severity
Dunaway S
Female
Finkel R S
Flickinger J
Glanzman A M
Humans
Infant
Kaufmann P
Male
Martens W B
McDermott M P
Montes J
Motor Skills/physiology
Muscle Study Group
natural-history
O'Hagen J
outcome assessment
Pediatric Neuromuscular Clinical Research
Pediatric Physical Therapy
Pediatrics
physical therapy/methods
Preschool
Psychometrics/methods
Quigley J
Rehabilitation
Riley S
scale development
Severity Of Illness Index
Sma
SMA1
smn2 copy number
spinal muscular
spinal muscular atrophies of
spinal muscular-atrophy
Sproule D
Tawil R
tone and motor problems
tool development
Validity
Yang M
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/ajmg.a.31623" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ajmg.a.31623</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Behavioral problems in relation to intelligence in children with 22q11.2 deletion syndrome: a matched control study
Publisher
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American Journal of Medical Genetics Part A
Date
A point or period of time associated with an event in the lifecycle of the resource
2007
Subject
The topic of the resource
Male; Case-Control Studies; Child; Humans; Child Behavior Disorders/psychology; Female; Reproducibility of Results; Syndrome; Psychometrics/methods; Chromosome Deletion; Chromosomes Human Pair 22; Intelligence; Abnormalities Multiple/genetics/pathology/psychology; Craniofacial Abnormalities/psychology; behavioral problems; 22q11.2 deletion syndrome; trajectory; characteristics
Creator
An entity primarily responsible for making the resource
Jansen P W; Duijff S N; Beemer F A; Vorstman J A; Klaassen P W; Morcus M E; Heineman-de B J A
Description
An account of the resource
The 22q11.2 deletion syndrome (22q11DS) is a genetic disorder associated with palatal abnormalities, cardiac defects, a characteristic facial appearance, learning difficulties, and delays in speech and language development. Various behavioral disorders and psychiatric illnesses have also been reported. There is much debate as to whether the behavioral problems are caused by factors such as medical discomfort, facial abnormalities or a lower intelligence, or whether they are independently related to the genetic abnormality ("behavioral phenotype"). We examined the relationship between intelligence level and behavioral problems. A group of 69 children with 22q11DS was compared with 69 children with craniofacial anomalies (CFA) using the child behavior checklist (CBCL). The matches between individual children were based on their total IQ scores. Use of the CBCL norm scores covered the corrections for age and sex. The group of 22q11DS children showed significantly more behavioral problems than the CFA group: this was especially apparent on the CBCL subscales "withdrawn," "anxious/depressed," "delinquent behavior," "aggressive behavior," "somatic complaints," and "social problems." We found no correlation between IQ score and behavioral problems in the 22q11DS group, which was remarkable because, comparable with the general population, intellectual disabilities were a predictor of behavioral problems in the CFA group. 22q11DS children with relatively higher IQs showed more problems of an internalizing than an externalizing nature, whereas the 22q11DS children with lower IQs showed various behavioral problems. The absence of a statistically significant correlation between intelligence and behavior problems in the group of 22q11DS children is tentative evidence for a 22q11DS behavioral phenotype.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/ajmg.a.31623" target="_blank" rel="noreferrer noopener">10.1002/ajmg.a.31623</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2007
22q11.2 Deletion Syndrome
Abnormalities Multiple/genetics/pathology/psychology
American Journal of Medical Genetics Part A
Beemer F A
behavioral problems
Case-Control Studies
characteristics
Child
Child Behavior Disorders/psychology
Chromosome Deletion
Chromosomes Human Pair 22
Craniofacial Abnormalities/psychology
Duijff S N
Female
Heineman-de B J A
Humans
Intelligence
Jansen P W
Klaassen P W
Male
Morcus M E
Psychometrics/methods
Reproducibility of Results
Syndrome
Trajectory
Vorstman J A