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Text
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Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1155/2004/370915" target="_blank" rel="noreferrer">http://doi.org/10.1155/2004/370915</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Treatment of pediatric chronic pain with tramadol hydrochloride: siblings with Ehlers-Danlos syndrome - Hypermobility type
Publisher
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Pain Research & Management
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
Subject
The topic of the resource
Child; Humans; Male; Analgesics; Preschool; Chronic disease; Pain/drug therapy/etiology; Opioid/administration & dosage; Ehlers-Danlos Syndrome/complications; Joint Instability/etiology; Tramadol/administration & dosage
Creator
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Brown SC; Stinson J
Description
An account of the resource
OBJECTIVE: To evaluate the effectiveness of tramadol hydrochloride for the treatment of chronic pain refractory to previous treatment in two pediatric patients. METHODS: Tramadol hydrochloride was administered (50 mg/day to 150 mg/day) to two siblings with Ehlers-Danlos syndrome - Hypermobility type refractory to previous pharmacological treatments, and changes in pain intensity and physical activity were assessed. RESULTS: Pain intensity decreased and physical activity improved within days of starting therapy. Positive results have been maintained for 30 months. CONCLUSIONS: Tramadol hydrochloride was a safe and effective treatment for relieving chronic pain in two pediatric patients suffering from the hypermobility type of Ehlers-Danlos syndrome. No morbidity or side effects were noted during the 30-month follow-up.
2004
Identifier
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<a href="http://doi.org/10.1155/2004/370915" target="_blank" rel="noreferrer">10.1155/2004/370915</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2004
Analgesics
Backlog
Brown SC
Child
Chronic Disease
Ehlers-Danlos Syndrome/complications
Humans
Joint Instability/etiology
Journal Article
Male
Opioid/administration & dosage
Pain Research & Management
Pain/drug therapy/etiology
Preschool
Stinson J
Tramadol/administration & dosage
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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PedPalASCNet Member Publications
Subject
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A collection of relevant articles published by one or more of PedPalASCNet's members
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805346/" target="_blank" rel="noreferrer">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805346/</a>
Notes
<p>1918-1523<br />Siden, Harold B<br />Carleton, Bruce C<br />Oberlander, Tim F<br />Clinical Trial<br />Journal Article<br />Research Support, Non-U.S. Gov't<br />United States<br />Pain Res Manag. 2013 Sep-Oct;18(5):243-8. Epub 2013 Jul 24.</p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
Title
A name given to the resource
Physician Variability In Treating Pain And Irritability Of Unknown Origin In Children With Severe Neurological Impairment
Publisher
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Pain Research & Management
Subject
The topic of the resource
Adolescent; Analgesics/ Therapeutic Use; Child; Developmental Disabilities/ Complications; Female; Humans; Male; Pain/complications/ Drug Therapy; Pain Management/ Methods; Pilot Projects; Practice Patterns Physicians'/ Statistics & Numerical Data
Creator
An entity primarily responsible for making the resource
Siden H; Carleton BC; Oberlander TF
Description
An account of the resource
BACKGROUND: Pain and irritability of unknown origin (PIUO) is a challenging problem for nonverbal children with severe neurological impairments. PIUO is not associated with an identifiable source of nociceptive-inflammatory or neuropathic pain. OBJECTIVE: To assess how physicians use pharmacotherapy to treat PIUO, and to report a pilot study of a standardized approach to investigating and treating PIUO. METHOD: Part 1 of the present study involved independently presenting a case vignette of a patient with PIUO to six experienced physicians who care for children with neurological impairments. They were asked for medication choices and sequences to empirically treat PIUO. Part 2 was a pilot study of a PIUO protocol. Patients followed a standard pathway for PIUO, referred to as the pathway for unknown pain (PUP). The initial drug sequence for the PUP was based on Part 1. RESULTS: In Part 1, physicians responding to the case vignette listed eight medications (atypical antipsychotics, benzodiazepines, gabapentin, methadone, opioids, selective serotonin reuptake inhibitors, tramadol and tricylic antidepressants) and eight empiric drug sequences. In Part 2, eight children with PIUO (six to 17 years of age; five females, three males) were enrolled in a pilot clinic. Only two had been fully evaluated for nociceptive-inflammatory pain sources before enrollment. At the end of the pilot study, four patients were clinically improved and only three required a study medication. DISCUSSION AND CONCLUSION: Even experienced physicians do not agree on a common approach for medical treatment of PIUO. A standardized pathway is feasible and readily implemented. The proposed PUP has the potential to address PIUO and be the basis for future intervention studies.
Identifier
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<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805346/" target="_blank" rel="noreferrer">PMC3805346/</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2013
Adolescent
Analgesics/ Therapeutic Use
Carleton BC
Child
Developmental Disabilities/ Complications
Female
Humans
Male
Oberlander TF
Pain and Irritability Project
Pain Management/ Methods
Pain Research & Management
Pain/complications/ Drug Therapy
Physician Variability In Treating Pain And Irritability Of Unknown Origin In Children With Severe Neurological Impairment
Pilot Projects
Practice Patterns Physicians'/ Statistics & Numerical Data
Siden H