1
40
210
-
Text
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Citation List Month
July 2016 List
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Dying Later, Surviving Longer
Publisher
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Archives Of Disease In Childhood
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
Life; Pediatrics; Child; Death; Mortality; Decision Making; Intensive Care; Chronic Illnesses; Pain; Demographics; Children & Youth
Epidemiology; Ethics; Intensive Care; Mortality
Creator
An entity primarily responsible for making the resource
Wilkinson D; J Weitz
Description
An account of the resource
Most children who die in the UK have an underlying chronic illness, and the majority of these deaths take place in a paediatric intensive care unit (PICU).1 The overall community burden of paediatric chronic illness is increasing as the population expands and as children with chronic conditions live longer. Improvements in public health measures, and in the recognition and management of paediatric critical illness, mean that children with chronic conditions are increasingly the majority population in PICU.
Plunkett and Parslow describe a shift in the timing of death in PICUs in England and Wales over the last decade.2 They observed an increase in the average length of stay for children who died (about 3 days longer, on average, in 2013 than in 2003) and a corresponding increase in the proportion of children dying after more than 4 weeks of intensive care; in 2013, approximately 12% of deaths in PICU occurred late (after 28 days), compared with only about 8% a decade earlier.
What should we make of this finding? Does it represent a failure of end-of-life decision-making? Plunkett and Parslow point to this, suggesting that children with life-limiting illnesses are now dying after a long PICU admission rather than experiencing an early death in PICU.
Identifier
An unambiguous reference to the resource within a given context
doi:10.1136/archdischild-2016-310637
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
Archives of Disease in Childhood
Child
Children & Youth
Chronic Illnesses
Death
Decision Making
Demographics
Epidemiology
Ethics
Intensive Care
J Weitz
July 2016 List
Life
Mortality
Pain
Pediatrics
Wilkinson D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
July 2016 List
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Young Children's Ability To Report On Past, Future, And Hypothetical Pain States: A Cognitive-developmental Perspective
Publisher
An entity responsible for making the resource available
Pain
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
Declarative Memory; Randomized-trial; Mental Time-travel; Recall; Needle Pain; Child; Clinical Neurology; Age-children; Cognitive-development; Medical Procedures; Attention; Self-report; Memory; Pain Assessment; Intensity; Neurosciences; Anesthesiology; Self
Creator
An entity primarily responsible for making the resource
Jaaniste T
Description
An account of the resource
Children are at times asked by clinicians or researchers to rate their pain associated with their past, future, or hypothetical experiences. However, little consideration is typically given to the cognitive-developmental requirements of such pain reports. Consequently, these pain assessment tasks may exceed the abilities of some children, potentially resulting in biased or random responses. This could lead to the over- or under-treatment of children's pain. This review provides an overview of factors, and specifically the cognitive-developmental prerequisites, that may affect a child's ability to report on nonpresent pain states, such as past, future, or hypothetical pain experiences. Children's ability to report on past pains may be influenced by developmental (age, cognitive ability), contextual (mood state, language used by significant others), affective and pain-related factors. The ability to mentally construct and report on future painful experiences may be shaped by memory of past experiences, information provision and learning, contextual factors, knowledge about oneself, cognitive coping style, and cognitive development. Hypothetical pain reports are sometimes used in the development and validation of pain assessment scales, as a tool in assessing cognitive-developmental and social-developmental aspects of children's reports of pain, and for the purposes of training children to use self-report scales. Rating pain associated with hypothetical pain scenarios requires the ability to recognize pain in another person and depends on the child's experience with pain. Enhanced understanding of cognitive-developmental requirements of young children's pain reports could lead to improved understanding, assessment, and treatment of pediatric pain.
Identifier
An unambiguous reference to the resource within a given context
DOI: 10.1097/j.pain.0000000000000666
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
Age-children
Anesthesiology
Attention
Child
Clinical Neurology
Cognitive-development
Declarative Memory
Intensity
Jaaniste T
July 2016 List
Medical Procedures
Memory
Mental Time-travel
Needle Pain
Neurosciences
Pain
Pain Assessment
Randomized-trial
Recall
Self
Self-report
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
June 2017 List
URL Address
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1583746
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Family-oriented Palliative Care: Parents' Perspective And Experience
Publisher
An entity responsible for making the resource available
Neuropediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
Family Study; Palliative Therapy; Brain Damage; Child; Chromosome Disorder; Chromosome Disorders; Complication; Controlled Study; Dyspnea; Gene Deletion; Hospice; Hospital; Human; Length Of Stay; Life Expectancy; Medical Service; Metabolic Disorder; Neuromuscular Disease; Only Child; Pain; Palliative Care; Quality Of Life; Seizure; Spasticity; Spiritual Care; Symptom
Creator
An entity primarily responsible for making the resource
Pietz J
Description
An account of the resource
Palliative care is needed for children with neurodegenerative and progressive neuromuscular diseases, inborn genetic (e.g., chromosomal disorders, deletion syndromes) or metabolic disorders, as well as for children with early brain lesions which can decrease life-expectancy due to complications. Care for children with life-shortening diseases is a major challenge for parents and the whole family. A vast majority of families prefer to live at home with their severely sick child, and they also want to avoid admissions to hospital and stay at their familiar environment for the final period of life. To cope with all these demands, many families need a lot of support. By means of early integration of palliative perspective and care support can be adapted to the needs of the child and the family. Many children are living at home with their parents for many years. In many cases, quality of life and a stable familiar environment can be assured only by substantial external assistance. Support by specialized palliative care teams (SAPV), hospices and hospice services is able to unburden families. Important tasks are continuous and 24-hour medical services for symptom control (regarding e.g., pain, dyspnea, seizures, spasticity) as well as psychological, emotional, social and spiritual care for patients and all other family members.
Identifier
An unambiguous reference to the resource within a given context
DOI: 10.1055/s-0036-1583746
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
Brain Damage
Child
Chromosome Disorder
Chromosome Disorders
Complication
Controlled Study
Dyspnea
Family Study
Gene Deletion
Hospice
Hospital
Human
June 2017 List
Length Of Stay
Life Expectancy
Medical Service
Metabolic Disorder
Neuromuscular Disease
Neuropediatrics
Only Child
Pain
Palliative Care
Palliative Therapy
Pietz J
Quality Of Life
Seizure
Spasticity
Spiritual Care
Symptom
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
June 2017 List
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Aspects Of Palliative Care In Child Neurology
Publisher
An entity responsible for making the resource available
Neuropediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
Neurology; Palliative Therapy; Bereavement Counseling; Central Nervous System Tumor; Child; Child Care; Chromosome Aberration; Controlled Study; Coordination; Diagnosis; Family Study; Germany; Human; Human Experiment; Metabolic Disorder; Neurologic Disease; Only Child; Pain; Palliative Care; Quality Of Life; Spiritual Care; Terminal Care
Creator
An entity primarily responsible for making the resource
Nolte-Buchholtz S; Von Der Hagen M
Description
An account of the resource
Pediatric palliative medicine/care (PPC) is an approach to care that focuses on improving the quality of life of children facing a life limiting condition (LLC). LLCs are classified by the ACT (Association for children with life-threatening or terminal conditions and their families) concept in four groups: (i) conditions for which treatment may be feasible but can fail (ii) conditions in which premature deaths is inevitable but where long periods of participation in normal activities may be feasible (iii) progressive conditions without curative options where treatment is exclusively palliative (iv) irreversible but non-progressive conditions causing likelihood of premature death through complications. Neurological LLCs in children are represented in all four groups according to the ACT concept. Furthermore neuropediatric LLCs comprise up to 70% of the diagnoses in PPC subject to the criteria of a neurological disease entity (inclusion of CNS tumors, chromosomal anomalies, metabolic disorders etc.). The clinical course in neuropediatric LLCs differs from the course of oncological LLCs. Therefore the needs of the affected children, their families and their requirements of the PPC providers are different. In Germany PPC is often recognized solely as an end of life care. Typically, PPC accomplishes the objective of improving quality of life through symptom management e.g., pain control, coordination of care, communication and by providing psychosocial and spiritual support to the child and the family also in bereavement counseling. Within in the last years three different levels of specialized PPC have been established in Germany.
Identifier
An unambiguous reference to the resource within a given context
DOI: 10.1055/s-0036-1583743
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
Bereavement Counseling
Central Nervous System Tumor
Child
Child Care
Chromosome Aberration
Controlled Study
Coordination
Diagnosis
Family Study
Germany
Human
Human Experiment
June 2017 List
Metabolic Disorder
Neurologic Disease
Neurology
Neuropediatrics
Nolte-Buchholtz S
Only Child
Pain
Palliative Care
Palliative Therapy
Quality Of Life
Spiritual Care
Terminal Care
Von Der Hagen M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
October 2017 List
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Quality Of Care Collaborative For Paediatric Palliative Care In Australia (quocca)
Publisher
An entity responsible for making the resource available
Pediatric Blood And Cancer
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Australia; Palliative Therapy; Anxiety; Child; Clinical Trial; Diagnosis; Dyspnea; Education; Family Study; Female; Human; Major Clinical Study; Male; Nausea; Nurse; Pain; Patient Referral; Questionnaire; Seizure; Staff; Symptom; Telehealth; Terminal Care
Creator
An entity primarily responsible for making the resource
Herbert A; Irving H; Pedersen LA; Baggio S; Delaney A; Donovan L; McLarty A; Duc J; Slater P; Johnson S; Trethewie S; Ryan S; Hynson J; Duffield J; Fleming S; Heywood M; Phillips M; Momber S; Burr C
Description
An account of the resource
Background: Geography and population distribution present challenges to the care of children with life-limiting conditions (LLC) within Australia. Children and young people have unique needs in relation to the provision of palliative care within Australia. Objectives: This project aims to improving the quality of care provided to children in close proximity to their home through educational initiatives. This is primarily delivered through "pop-up" education. 'Pop-up' education usually occurs (face-face or telehealth) when a specialist service is building capacity within a child and family's local community and creating a paediatric network. The education provided can be specific to symptom management, end of life care, physical aspects of patient care according to their individualised need and diagnosis and psychosocial needs. The setting is usually in a non-metropolitan location, and the education is provided in a timely manner in relation to the patient's needs. Design/Method: The project is a collaboration of the specialist paediatric palliative care services in each state of Australia. The project is being evaluated using pre and post intervention questionnaires completed by participants in the 'pop-up' educational initiatives. Evaluationwill consider factors such as knowledge, confidence and efficacy around providing care for children with LLC. Results: Forty-six "pop-up" education sessions had been delivered between June 2015 and November 2016. This has included each state and territory of Australia. There have been 507 participants in pop-up education sessions (92 hours of education). Nurses represented the largest group of attendees.Medical and allied health staff also attended demonstrating the need for education to applicable to an inter-disciplinary audience. To date there has been an improvement in the knowledge and confidence of participants to:* manage symptoms (pain, nausea, dyspnoea, seizures, and anxiety), * manage a new referral, * be aware of available resources* be confident in how to help a family prepare for a child's death* confidence in the provision of medications to children's receiving palliative care (including subcutaneous delivery). Conclusion: A collaboration of paediatric palliative care services providing education in a planned and co-ordinated way shows promise in increasing capacity for paediatric palliative care within Australia, and should assist achieving goals of the National Palliative Care Strategy 2010.
Identifier
An unambiguous reference to the resource within a given context
10.1002/pbc.26591
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
anxiety
Australia
Baggio S
Burr C
Child
Clinical Trial
Delaney A
Diagnosis
Donovan L
Duc J
Duffield J
Dyspnea
Education
Family Study
Female
Fleming S
Herbert A
Heywood M
Human
Hynson J
Irving H
Johnson S
Major Clinical Study
Male
McLarty A
Momber S
Nausea
Nurse
October 2017 List
Pain
Palliative Therapy
Patient Referral
Pedersen LA
Pediatric Blood and Cancer
Phillips M
Questionnaire
Ryan S
Seizure
Slater P
Staff
Symptom
Telehealth
Terminal Care
Trethewie S
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
October 2017 List
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Families Are Not The Barrier: Evaluating Attitudes Toward Early Integration Of Palliative Care In Pediatric Hematopoietic Stem Cell Transplant
Publisher
An entity responsible for making the resource available
Pediatric Blood And Cancer
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Family; Hematopoietic Stem Cell; Palliative Therapy; Anxiety; Attention; Child; Constipation; Diarrhea; Female; Graft Recipient; Human; Loss Of Appetite; Major Clinical Study; Male; Nausea; Pain; Parental Attitude; Quality Of Life; School Child; Speech; Symptom
Creator
An entity primarily responsible for making the resource
Levine D; Mandrell B; Sykes A; Baker J
Description
An account of the resource
Background: The benefits of early integration of palliative care (PC) in oncology have been well established yet, there remain significant barriers to PC integration, especially in the setting of pediatric hematopoietic stem cell transplant (HSCT). HSCT patients are prone to a great degree of treatment related toxicity and are at high risk for morbidity and mortality and, while ideally suited to benefit, inherent factors in this cure oriented field preclude the integration of PC services. Most notably, family receptivity to PC is often perceived as a barrier in HSCT yet there is no data on family attitudes toward PC in this setting. Objectives: This study aimed to evaluate perceived symptom burden in the first month of pediatric HSCT, as well as patient and parent attitudes toward early PC integration in pediatric HSCT. Design/Method: After IRB approval, development and pre-testing, novel survey tools were administered to HSCT patients and parents. Eligibility criteria included parent of an HSCT recipient < age 10 or patient/parent dyad for patients aged10 years or older, time from HSCT >1 month and <1 year, English-speaking, and consent/assent. Data was assessed for trends in response content frequencies, percentages and parent/child concordance. Results: 81 total participants were enrolled, including 60 parents and 21 patients. Analysis revealed high levels of perceived symptom related suffering in the first month of HSCT with suffering from: nausea 98.3%, loss of appetite 93.3%, pain 90%, diarrhea 88.3%, depression 75%, anxiety 70%, and constipation 41.7%. 85.7% of patients and 73.4% parents expressed that a great deal or a lot of attention should be paid to quality of life from the start of HSCT. The majority of patient and parent respondents (52.4/50%) indicated they would likely want to meet with PC early in HSCT and very few reported definite opposition (0% children, 3.3% parents). Conclusion: Pediatric HSCT patients experience a high degree of symptom related suffering, perceive quality of life as a high priority, and are largely in favor of early PC involvement. Our findings suggest that family receptivity should not be a barrier to early PC in pediatric HSCT and that aggressive cure directed therapy can and should be accompanied by aggressive quality of life directed care through early PC integration.
Identifier
An unambiguous reference to the resource within a given context
10.1002/pbc.26591
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
anxiety
Attention
Baker J
Child
Constipation
Diarrhea
Family
Female
Graft Recipient
Hematopoietic Stem Cell
Human
Levine D
Loss Of Appetite
Major Clinical Study
Male
Mandrell B
Nausea
October 2017 List
Pain
Palliative Therapy
Parental Attitude
Pediatric Blood and Cancer
Quality Of Life
School Child
Speech
Sykes A
Symptom
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
October 2017 List
Notes
<p>Using Smart Source Parsing<br />Date of Publication: 2017</p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
End-of-life And Bereavement Care In Pediatric Intensive Care Units
Publisher
An entity responsible for making the resource available
Pediatric Clinics Of North America
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Bereavement Support; Child Death; Family Interaction; Pediatric Intensive Care Unit; Child; Clinical Study; Doctor Patient Relation; Female; Health; Human; Male; Pain; Sound; Terminal Care; United States
Creator
An entity primarily responsible for making the resource
Suttle M; Jenkins T L; Tamburro R F
Description
An account of the resource
Most childhood deaths in the United States occur in hospitals. Pediatric intensive care clinicians must anticipate and effectively treat dying children's pain and suffering and support the psychosocial and spiritual needs of families. These actions may help family members adjust to their loss, particularly bereaved parents who often experience reduced mental and physical health. Candid and compassionate communication is paramount to successful end-of-life (EOL) care as is creating an environment that fosters meaningful family interaction. EOL care in the pediatric intensive care unit is associated with challenging ethical issues, of which clinicians must maintain a sound and working understanding.
Identifier
An unambiguous reference to the resource within a given context
10.1016/j.pcl.2017.06.012
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Bereavement Support
Child
Child Death
Clinical Study
Doctor Patient Relation
Family Interaction
Female
Health
Human
Jenkins T L
Male
October 2017 List
Pain
Pediatric Clinics of North America
Pediatric Intensive Care Unit
Sound
Suttle M
Tamburro R F
Terminal Care
United States
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
June 2017 List
URL Address
http://www.ncbi.nlm.nih.gov/pubmed/26858170
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Reiki Therapy For Symptom Management In Children Receiving Palliative Care: A Pilot Study
Publisher
An entity responsible for making the resource available
The American Journal Of Hospice & Palliative Care
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Anxiety; Pain; Palliative; Pediatric; Reiki; Symptom Management
Creator
An entity primarily responsible for making the resource
Thrane SE; Maurer SH; Dianxu Ren; Danford CA; Cohen Susan M
Description
An account of the resource
BACKGROUND: Pain may be reported in one-half to three-fourths of children with cancer and other terminal conditions and anxiety in about one-third of them. Pharmacologic methods do not always give satisfactory symptom relief. Complementary therapies such as Reiki may help children manage symptoms. OBJECTIVE: This pre-post mixed-methods single group pilot study examined feasibility, acceptability, and the outcomes of pain, anxiety, and relaxation using Reiki therapy with children receiving palliative care. METHODS: A convenience sample of children ages 7 to 16 and their parents were recruited from a palliative care service. Two 24-minute Reiki sessions were completed at the children's home. Paired t tests or Wilcoxon signed-rank tests were calculated to compare change from pre to post for outcome variables. Significance was set at P < .10. Cohen d effect sizes were calculated. RESULTS: The final sample included 8 verbal and 8 nonverbal children, 16 mothers, and 1 nurse. All mean scores for outcome variables decreased from pre- to posttreatment for both sessions. Significant decreases for pain for treatment 1 in nonverbal children ( P = .063) and for respiratory rate for treatment 2 in verbal children ( P = .009). Cohen d effect sizes were medium to large for most outcome measures. DISCUSSION: Decreased mean scores for outcome measures indicate that Reiki therapy did decrease pain, anxiety, heart, and respiratory rates, but small sample size deterred statistical significance. This preliminary work suggests that complementary methods of treatment such as Reiki may be beneficial to support traditional methods to manage pain and anxiety in children receiving palliative care.
Identifier
An unambiguous reference to the resource within a given context
10.1177/1049909116630973
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
anxiety
Cohen Susan M
Danford CA
Dianxu Ren
June 2017 List
Maurer SH
Pain
Palliative
Pediatric
Reiki
Symptom Management
The American Journal of Hospice & Palliative Care
Thrane SE
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
July 2017 List
Notes
<p>1743-0593<br />Harrop, Emily Jane<br />Brombley, Karen<br />Boyce, Katherine<br />Journal Article<br />England<br />Arch Dis Child Educ Pract Ed. 2017 May 9. pii: edpract-2016-312522. doi: 10.1136/archdischild-2016-312522.</p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Fifteen Minute Consultation: Practical Pain Management In Paediatric Palliative Care
Publisher
An entity responsible for making the resource available
Archives Of Disease In Childhood. Education And Practice Edition
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Neurodisability; Neuropathic; Oncology; Pain; Palliative
Creator
An entity primarily responsible for making the resource
Harrop EJ; Brombley K; Boyce K
Description
An account of the resource
Pain and distress in the paediatric palliative care population can be very difficult to manage. Clinical scenarios range from the acute management of cancer-related pain at the end of life to the ongoing long-term support of children with complex multimodal pain related to progressive neurological conditions. Understanding the child's underlying condition, possible causes of pain and their preferred mode of communication are important to the delivery of holistic care. Modification of environmental factors, basic care consideration and non-pharmacological measures have a large role to play, alongside conventional analgesics. Medication may also need to be delivered by novel routes such as transdermal patches, continuous subcutaneous infusion of multiple drugs or transmucosal breakthrough analgesic doses. Two cases are used to illustrate approaches to these clinical problems.
Identifier
An unambiguous reference to the resource within a given context
10.1136/archdischild-2016-312522
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Archives of Disease in Childhood. Education and Practice Edition
Boyce K
Brombley K
Harrop EJ
July 2017 List
Neurodisability
Neuropathic
Oncology
Pain
Palliative
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
December 2017 List
URL Address
<a href="http://doi.org/10.1016/j.jped.2017.07.014" target="_blank" rel="noreferrer">http://doi.org/10.1016/j.jped.2017.07.014</a>
Notes
<p>Using Smart Source Parsing<br />Date of Publication: 2017</p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pediatric chronic patients at outpatient clinics: A study in a Latin American University Hospital
Publisher
An entity responsible for making the resource available
Jornal De Pediatria.
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Chronic Patient; Emergency Ward; Hospital Admission; Hospitalization; Outpatient; University Hospital; Adolescent; Adult; Cardiology; Child; Controlled Study; Cross Sectional Study; Death; Emergency Health Service; Endocrinology; Female; Hematology; Human; Intensive Care Unit; Kidney Transplantation; Major Clinical Study; Male; Nephrology; Neurology; Oncology; Pain; Physician; Psychiatry; Rheumatology
Creator
An entity primarily responsible for making the resource
Alveno RA; Miranda CV; Passone CG; Waetge AR; Hojo ES; Farhat SCL; Odone-Filho V; Tannuri U; Carvalho WB; Carneiro-Sampaio M; Silva CA
Description
An account of the resource
Objective: To describe the characteristics of children and adolescentes with chronic diseases of outpatient clinics at a tertiary university hospital. Methods: A cross-sectional study was performed with 16,237 patients with chronic diseases followed-up in one year. The data were collected through the electronic system, according to the number of physician appointments in 23 pediatric specialties. Patients were divided in two groups: children (0-9 years) and adolescents (10-19 years). Early (10-14 years) and late (15-19 years) adolescent groups were also analyzed. Results: Of the total sample, 56% were children and 46% were adolescents. The frequencies of following pediatric specialties were significantly higher in adolescents when compared with children: cardiology, endocrinology, hematology, nephrology/renal transplantation, neurology, nutrology, oncology, palliative and pain care, psychiatry, and rheumatology (p <. 0.05). The frequencies of emergency service visits (30% vs. 17%, p <. 0.001), hospitalizations (23% vs. 11%, p <. 0.001), intensive care unit admissions (6% vs. 2%, p <. 0.001), and deaths (1% vs. 0.6%, p = 0.002) were significantly lower in adolescents than in children. However, the number of physician appointments (>=13) per patient was also higher in the adolescent group (5% vs. 6%, p = 0.018). Further analysis comparison between early and late adolescents revealed that the first group had significantly more physician appointments (35% vs. 32%, p = 0.025), and required more than two pediatric specialties (22% vs. 21%, p = 0.047). Likewise, the frequencies of emergency service visits (19% vs. 14%, p <. 0.001) and hospitalizations (12% vs. 10%, p = 0.035) were higher in early adolescents. Conclusions: This study evaluated a large population in a Latin American hospital and suggested that early adolescents with chronic diseases required many appointments, multiple specialties and hospital admissions.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jped.2017.07.014" target="_blank" rel="noreferrer">10.1016/j.jped.2017.07.014</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Adolescent
Adult
Alveno RA
Cardiology
Carneiro-Sampaio M
Carvalho WB
Child
Chronic Patient
Controlled Study
Cross Sectional Study
Death
December 2017 List
Emergency Health Service
Emergency Ward
Endocrinology
Farhat SCL
Female
Hematology
Hojo ES
Hospital Admission
Hospitalization
Human
Intensive Care Unit
Jornal De Pediatria.
Kidney Transplantation
Major Clinical Study
Male
Miranda CV
Nephrology
Neurology
Odone-Filho V
Oncology
Outpatient
Pain
Passone CG
Physician
Psychiatry
Rheumatology
Silva CA
Tannuri U
University Hospital
Waetge AR
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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PedPalASCNet Member Publications
Subject
The topic of the resource
A collection of relevant articles published by one or more of PedPalASCNet's members
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
n/a
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Using colors to assess pain in toddlers: validation of "the rainbow pain scale"-a proof-of-principle study.
Publisher
An entity responsible for making the resource available
Journal Of Pediatric Oncology Nursing : Official Journal Of The Association Of Pediatric Oncology Nurses
Date
A point or period of time associated with an event in the lifecycle of the resource
2014
Subject
The topic of the resource
Color; Age Factors; Child; Child Preschool; Female; Humans; Infant; Inpatients/psychology; Male; Neoplasms/psychology; Oncology; Oncology Nursing/methods; Outpatients/psychology; Pain; Pain/diagnosis/psychology; Pain Measurement/methods; Pain Scale; Pediatric Nursing/methods; Preschool Children; Psychometrics/instrumentation; Self Report
Creator
An entity primarily responsible for making the resource
Mahon P; Holsti L; Siden H; Strahlendorf C; Turnham L; Giaschi D
Description
An account of the resource
Self-report, when available, is considered the ideal way to assess the intensity and other aspects of pain in children. However, self-report scales are often too complex cognitively for preschool-aged children (2-4 years). The Rainbow Pain Scale (RPS) was developed to provide individualized self-reported pain ratings for preschool-aged children. The psychometric properties of this scale have yet to be evaluated. To ensure validity, our first step was to compare RPS scores to a well-validated scale in older children who were able to self-report their pain. The purpose of this study was to assess the concurrent validity of the RPS in children aged 5 to 10 years as proof of principle. We compared ratings of 49 children's pain using the RPS with those on the Faces Pain Scale-Revised (FPS-R). Participants suffering from pain related to cancer and cancer treatment were recruited to complete both scales at 3 time points, during both inpatient and outpatient clinic visits. Pearson's r and Cohen's kappa were used to evaluate the level of association between the scales. The association between RPS and the
Identifier
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<a href="http://doi.org/10.1177/1043454214555197" target="_blank" rel="noreferrer">10.1177/1043454214555197</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2014
Age Factors
Child
Child Preschool
Color
Female
Giaschi D
Holsti L
Humans
Infant
Inpatients/psychology
Journal Of Pediatric Oncology Nursing : Official Journal Of The Association Of Pediatric Oncology Nurses
Mahon P
Male
Neoplasms/psychology
Oncology
Oncology Nursing/methods
Outpatients/psychology
Pain
Pain Measurement/methods
Pain Scale
Pain/diagnosis/psychology
Pediatric Nursing/methods
Preschool Children
Psychometrics/instrumentation
Self Report
Siden H
Strahlendorf C
Turnham L
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Oncology
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Oncology 2017 List
URL Address
<a href="http://doi.org/10.1080/07347332.2016.1147913" target="_blank" rel="noreferrer">http://doi.org/10.1080/07347332.2016.1147913</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
"His ears are so soft!" Animal-assisted interventions in oncology settings: Implications for oncology social work practice
Publisher
An entity responsible for making the resource available
Journal Of Psychosocial Oncology
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
Clinical Practice; Ear; Oncology; Skill; Social Work Practice; 50-56-6 (oxytocin); 51-61-6 (dopamine); 62-31-7 (dopamine); 54577-94-5 (oxytocin); 60118-07-2 (endorphin); Adult; Animal Experiment; Animal Model; Anxiety; Blood Pressure; Cancer Patient; Cancer Therapy; Cerebrovascular Accident; Distress Syndrome; Dog; Dopamine; Endogenous Compound; Endorphin; Family Study; Female; Gene Expression; Happiness; Heart Rate; Hospice; Hospital Patient; Human; Human Versus Animal Comparison; Infusion; Male; Narrative; Nonhuman; Oxytocin; Pain; Palliative Therapy; Pet Therapy; Program Development; Recreation; Social Support; Storytelling; Symptom; Total Quality Management; Trust; Volunteer; Waiting Room
Creator
An entity primarily responsible for making the resource
Bach C
Description
An account of the resource
Content: The use of recreational, expressive, and integrative methods of providing supportive care to patients and families coping with cancer is growing in cancer treatment settings. One such method is animal-assisted interventions (AAI). From the clinic to the infusion suite, to the palliative care office, and to the inpatient hospice, the presence of therapy animals provides an another layer of therapeutic intervention to assist in coping with cancer. AAI can provide cancer patients with an opportunity for emotional support, diversion, recreation, sensory integration/tactile benefit, social support, companionship, and relief of distress and symptoms including pain, depression, anxiety, and isolation. Research also suggests that the simple act of petting a dog can lower heart rate and blood pressure (Friedman, 2015), as well as increase levels of oxytocin, dopamine, and endorphins (Uyemura, 2013). Oxytocin influences happiness and trust in individuals. "Oxytocin has some powerful effects for us in the body's ability to be in a state of readiness to heal.so it predisposes us to an environment in our bodies where we can be healthier" (http://www.npr.org/sections/health-shots/2012/03/09/146583986/ pet-therapy-how-animals-and-humans-heal-each-other). In addition, the therapy animal serves as a vehicle of communication, narrative, and storytelling. Imagine a patient sitting anxiously in the waiting room. He or she strokes the therapy dog gently and is taken to another time and place without cancer. He or she reflects on his or her own dog's roles in his or her life, how he or she rescued the dog, plays with the dog, sleeps with the dog. He or she is distracted, relaxed, and utilizing his or her own story to invoke feelings of happiness, normalcy, and hope. This presentation will examine the history, function, and roles of animal-assisted therapy and activities in various settings. The benefits of AAI with cancer patients (both adults and children) as well as with oncology professionals will also be presented. AAI as a method of integrative supportive oncology therapy will be addressed. The benefits of AAI as well as barriers and limitations for these programs in oncology settings will be reviewed. We will explore AAI program development and evaluation through presentation of results from quality improvement surveys completed by program participants. Suggestions for program development, volunteer recruitment and retention, and therapy dog support will also be discussed. Case presentations of AAI in action from various oncology settings will be a highlight of this presentation.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1080/07347332.2016.1147913" target="_blank" rel="noreferrer">10.1080/07347332.2016.1147913</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
50-56-6 (oxytocin)
51-61-6 (dopamine)
54577-94-5 (oxytocin)
60118-07-2 (endorphin)
62-31-7 (dopamine)
Adult
Animal Experiment
Animal Model
anxiety
Bach C
Blood Pressure
Cancer Patient
Cancer Therapy
Cerebrovascular Accident
Clinical Practice
Distress Syndrome
Dog
Dopamine
Ear
Endogenous Compound
Endorphin
Family Study
Female
Gene Expression
Happiness
Heart Rate
Hospice
Hospital Patient
Human
Human Versus Animal Comparison
Infusion
Journal Of Psychosocial Oncology
Male
Narrative
Nonhuman
Oncology
Oncology 2017 List
Oxytocin
Pain
Palliative Therapy
Pet Therapy
Program Development
Recreation
Skill
Social Support
Social Work Practice
Storytelling
Symptom
Total Quality Management
Trust
Volunteer
Waiting Room
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Oncology
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Oncology 2017 List
URL Address
<a href="http://doi.org/10.1016/j.jpainsymman.2016.09.012" target="_blank" rel="noreferrer">http://doi.org/10.1016/j.jpainsymman.2016.09.012</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Home-Based Palliative Care for Children With Incurable Cancer: Long-term Perspectives of and Impact on General Practitioners
Publisher
An entity responsible for making the resource available
Journal Of Pain And Symptom Management
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Cancer Epidemiology; General Practitioner; Palliative Therapy; Child; Controlled Study; Cross-sectional Study; Death; Distress Syndrome; Doctor Patient Relation; Fatigue; Human; Human Versus Animal Comparison; Major Clinical Study; Nonhuman; Pain; Panic; Powerlessness; Questionnaire; Sadness; Symptom; Thermometer
Creator
An entity primarily responsible for making the resource
van der Geest IMM; Bindels PJE; Pluijm SMF; Michiels EMC; van der Heide A; Pieters R; Darlington ASE; van den Heuvel-Eibrink MM
Description
An account of the resource
Context: Although a large percentage of children with advanced-stage cancer die at home, remarkably little information is available regarding the experience of general practitioners (GPs) with respect to providing home-based palliative care to children with incurable cancer. Objectives: The objective of this study was to explore the perspectives of GPs who care for children with advanced-stage cancer in a home-based setting. Methods: In this cross-sectional study, 144 GPs who provided home-based palliative care to 150 children with incurable cancer from 2001 through 2010 were invited to complete a questionnaire addressing their perspectives regarding: 1) symptom management, 2) collaboration with other health care professionals, 3) the child's death and care after death, and 4) impact of having provided palliative care, scored on distress thermometer (range 0-10). Results: A total of 112 GPs (78%) responded, and 91 GPs completed the questionnaire for 93 patients. The median interval between the child's death and completing the questionnaire was seven years. The most prevalent symptoms reported in the patients were fatigue (67%) and pain (61%). Difficulties with communicating with (14%), coordinating with (11%), collaborating with (11%), and contacting (2%) fellow members of the multidisciplinary treatment team were rare. Hectic (7%) and shocking (5%) situations and panic (2%) around the child's death were rare. GPs reported feelings of sadness (61%) and/or powerlessness (43%) around the time of the patient's death, and they rated their own distress level as relatively high during the terminal phase (median score 6, range 0-9.5). The majority of GPs (94%) reported that they ultimately came to terms with the child's death. Conclusion: In general, GPs appear to be satisfied with the quality of home-based palliative care that they provide pediatric patients with incurable cancer. Communication among health care professionals is generally positive and is considered important. Finally, although the death of a pediatric patient has a profound impact on the GP, the majority of GPs eventually come to terms with the child's death. Copyright _ 2017 American Academy of Hospice and Palliative Medicine.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jpainsymman.2016.09.012" target="_blank" rel="noreferrer">10.1016/j.jpainsymman.2016.09.012</a>
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Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Bindels PJE
Cancer Epidemiology
Child
Controlled Study
Cross-sectional Study
Darlington ASE
Death
Distress Syndrome
Doctor Patient Relation
Fatigue
General Practitioner
Human
Human Versus Animal Comparison
Journal of Pain and Symptom Management
Major Clinical Study
Michiels EMC
Nonhuman
Oncology 2017 List
Pain
Palliative Therapy
Panic
Pieters R
Pluijm SMF
Powerlessness
Questionnaire
Sadness
Symptom
Thermometer
van den Heuvel-Eibrink MM
van der Geest IMM
van der Heide A
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Oncology
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Oncology 2017 List
URL Address
<a href="http://doi.org/10.1002/pbc.26589" target="_blank" rel="noreferrer">http://doi.org/10.1002/pbc.26589</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Practice patterns of palliative radiation therapy in pediatric oncology patients in an international pediatric research consortium
Publisher
An entity responsible for making the resource available
Pediatric Blood And Cancer
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Childhood Cancer/rt [radiotherapy]; Palliative Therapy; Anesthesia; Article; Brain Metastasis; Cancer Patient; Child; Cone Beam Computed Tomography; Conformal Radiotherapy; Electron Therapy; Ependymoma; Ewing Sarcoma; Health Survey; Histopathology; Human; Intensity Modulated Radiation Therapy; Intestine Obstruction; Leukemia; Lymphoma; Major Clinical Study; Malignant Neoplasm; Medulloblastoma; Metastasis; Neuroblastoma; Osteosarcoma; Pain; Primary Tumor; Priority Journal; Proton Therapy; Radiation Dose Fractionation; Radiosensitivity; Re-irradiation; Respiratory Tract Disease; Rhabdomyosarcoma; Spinal Cord Compression; Stereotactic Body Radiation Therapy; Stomach Distension
Creator
An entity primarily responsible for making the resource
Rao AD; Chen Q; Ermoian RP; Alcorn SR; Figueiredo MLS; Chen MJ; Dieckmann K; MacDonald SM; Ladra MM; Kobyzeva D; Nechesnyuk AV; Nilsson K; Ford EC; Winey BA; Villar RC; Terezakis SA
Description
An account of the resource
Background/Objectives: The practice of palliative radiation therapy (RT) is based on extrapolation from adult literature. We evaluated patterns of pediatric palliative RT to describe regimens used to identify opportunity for future pediatric-specific clinical trials. Design/Methods: Six international institutions with pediatric expertise completed a 122-item survey evaluating patterns of palliative RT for patients <=21 years old from 2010 to 2015. Two institutions use proton RT. Palliative RT was defined as treatment with the goal of symptom control or prevention of immediate life-threatening progression. Results: Of 3,225 pediatric patients, 365 (11%) were treated with palliative intent to a total of 427 disease sites. Anesthesia was required in 10% of patients. Treatment was delivered to metastatic disease in 54% of patients. Histologies included neuroblastoma (30%), osteosarcoma (18%), leukemia/lymphoma (12%), rhabdomyosarcoma (12%), medulloblastoma/ependymoma (12%), Ewing sarcoma (8%), and other (8%). Indications included pain (43%), intracranial symptoms (23%), respiratory compromise (14%), cord compression (8%), and abdominal distention (6%). Sites included nonspine bone (35%), brain (16% primary tumors, 6% metastases), abdomen/pelvis (15%), spine (12%), head/neck (9%), and lung/mediastinum (5%). Re-irradiation comprised 16% of cases. Techniques employed three-dimensional conformal RT (41%), intensity-modulated RT (23%), conventional RT (26%), stereotactic body RT (6%), protons (1%), electrons (1%), and other (2%). The most common physician-reported barrier to consideration of palliative RT was the concern about treatment toxicity (83%). Conclusion: There is significant diversity of practice in pediatric palliative RT. Combined with ongoing research characterizing treatment response and toxicity, these data will inform the design of forthcoming clinical trials to establish effective regimens and minimize treatment toxicity for this patient population.
Identifier
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<a href="http://doi.org/10.1002/pbc.26589" target="_blank" rel="noreferrer">10.1002/pbc.26589</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Alcorn SR
Anesthesia
Article
Brain Metastasis
Cancer Patient
Chen MJ
Chen Q
Child
Childhood Cancer/rt [radiotherapy]
Cone Beam Computed Tomography
Conformal Radiotherapy
Dieckmann K
Electron Therapy
Ependymoma
Ermoian RP
Ewing Sarcoma
Figueiredo MLS
Ford EC
Health Survey
Histopathology
Human
Intensity Modulated Radiation Therapy
Intestine Obstruction
Kobyzeva D
Ladra MM
Leukemia
Lymphoma
MacDonald SM
Major Clinical Study
Malignant Neoplasm
Medulloblastoma
Metastasis
Nechesnyuk AV
Neuroblastoma
Nilsson K
Oncology 2017 List
Osteosarcoma
Pain
Palliative Therapy
Pediatric Blood and Cancer
Primary Tumor
Priority Journal
Proton Therapy
Radiation Dose Fractionation
Radiosensitivity
Rao AD
Re-irradiation
Respiratory Tract Disease
Rhabdomyosarcoma
Spinal Cord Compression
Stereotactic Body Radiation Therapy
Stomach Distension
Terezakis SA
Villar RC
Winey BA
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.3928/00904481-20120727-13" target="_blank" rel="noreferrer">http://doi.org/10.3928/00904481-20120727-13</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pediatric palliative pain and symptom management
Publisher
An entity responsible for making the resource available
Pediatric Annals
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
Subject
The topic of the resource
Child; Humans; Palliative Care; Pain; Pain Management; Analgesics; Opioid; Disease Management
Creator
An entity primarily responsible for making the resource
Shaw TM
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3928/00904481-20120727-13" target="_blank" rel="noreferrer">10.3928/00904481-20120727-13</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2012
Analgesics
Backlog
Child
Disease Management
Humans
Journal Article
Opioid
Pain
Pain Management
Palliative Care
Pediatric Annals
Shaw TM
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2066846" target="_blank" rel="noreferrer">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2066846</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Comparison of morphine and methadone for prevention of postoperative pain in 3- to 7-year-old children
Publisher
An entity responsible for making the resource available
Journal Of Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
Subject
The topic of the resource
Child; Female; Male; Pain; Pain Measurement; Prospective Studies; Analysis of Variance; Double-Blind Method; Preschool; Non-U.S. Gov't; Comparative Study; Drug Evaluation; Human; Support; Postoperative/prevention & control; algorithms; Intraoperative Care; Methadone/adverse effects/pharmacokinetics/therapeutic use; Morphine/adverse effects/therapeutic use
Creator
An entity primarily responsible for making the resource
Berde CB; Beyer JE; Bournaki MC; Levin CR; Sethna NF
Description
An account of the resource
A randomized, double-blind, prospective study was performed to determine the effects of perioperative administration of morphine or methadone on postoperative analgesic requirements and pain scores in 35 children aged 3 to 7 years undergoing major surgery. After a standardized induction of anesthesia, methadone or morphine, 0.2 mg/kg, was blindly administered, and supplemental doses were titrated to achieve comfort in the recovery room. Pain was assessed during the next 36 hours with a combination of validated behavioral and self-report measures. Patients in the methadone group required fewer supplemental opioid analgesic drugs during the next 36 hours, and reported lower pain scores. No patient had prolonged emergence from anesthesia, and no patient required naloxone or postoperative ventilatory assistance. No major adverse events occurred. We conclude that perioperative intravenous administration of methadone is an effective, inexpensive, and technologically simple means for providing prolonged analgesia for children after surgery.
1991
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1991
algorithms
Analysis of Variance
Backlog
Berde CB
Beyer JE
Bournaki MC
Child
Comparative Study
Double-Blind Method
Drug Evaluation
Female
Human
Intraoperative Care
Journal Article
Journal of Pediatrics
Levin CR
Male
Methadone/adverse effects/pharmacokinetics/therapeutic use
Morphine/adverse effects/therapeutic use
Non-U.S. Gov't
Pain
Pain Measurement
Postoperative/prevention & control
Preschool
Prospective Studies
Sethna NF
Support
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11573533" target="_blank" rel="noreferrer">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11573533</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Codeine phosphate in paediatric medicine
Publisher
An entity responsible for making the resource available
British Journal Of Anaesthesia
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
Subject
The topic of the resource
Child; Pain; Analgesics; Non-U.S. Gov't; Human; Support; Postoperative/drug therapy; Codeine/pharmacokinetics/pharmacology/therapeutic use; Opioid/pharmacokinetics/pharmacology/therapeutic use
Creator
An entity primarily responsible for making the resource
Williams DG; Hatch DJ; Howard RF
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2001
2001
Analgesics
Backlog
British Journal Of Anaesthesia
Child
Codeine/pharmacokinetics/pharmacology/therapeutic use
Hatch DJ
Howard RF
Human
Journal Article
Non-U.S. Gov't
Opioid/pharmacokinetics/pharmacology/therapeutic use
Pain
Postoperative/drug therapy
Support
Williams DG
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11573519" target="_blank" rel="noreferrer">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11573519</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Codeine phosphate in children: time for re-evaluation?
Publisher
An entity responsible for making the resource available
British Journal Of Anaesthesia
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
Subject
The topic of the resource
Child; Pain; Analgesics; Evidence-Based Medicine; infant; Human; Opioid/therapeutic use; Postoperative/drug therapy; Codeine/therapeutic use
Creator
An entity primarily responsible for making the resource
Cunliffe M
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2001
2001
Analgesics
Backlog
British Journal Of Anaesthesia
Child
Codeine/therapeutic use
Cunliffe M
Evidence-based Medicine
Human
Infant
Journal Article
Opioid/therapeutic use
Pain
Postoperative/drug therapy
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://adc.bmj.com/content/85/6/460" target="_blank" rel="noreferrer">http://adc.bmj.com/content/85/6/460</a>
Dublin Core
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Title
A name given to the resource
Pain in cognitively impaired, non-communicating children
Publisher
An entity responsible for making the resource available
Archives Of Disease In Childhood
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
Subject
The topic of the resource
Pain; cognitive impairment; non-communicating
Creator
An entity primarily responsible for making the resource
Stallard P; Williams L; Lenton S; Velleman R
Description
An account of the resource
AIM To detail the everyday occurrence of pain in non-communicating children with cognitive impairment. METHODS Thirty four parents of cognitively impaired verbally non-communicating children completed pain diaries over a two week period. Each day, for five defined periods, parents rated whether their child had been in pain, and if so, its severity and duration. RESULTS Twenty five (73.5%) children experienced pain on at least one day, with moderate or severe levels of pain being experienced by 23 (67.6%). Four children (11.7%) experienced moderate or severe pain lasting longer than 30 minutes on five or more days. No child was receiving active pain management. CONCLUSIONS Everyday pain in children with severe cognitive impairment is common, yet is rarely actively treated.
2001-12
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2001
Archives of Disease in Childhood
Backlog
cognitive impairment
Journal Article
Lenton S
non-communicating
Pain
Stallard P
Velleman R
Williams L
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.2165/00003088-199733030-00005" target="_blank" rel="noreferrer">http://doi.org/10.2165/00003088-199733030-00005</a>
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Title
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Pharmacokinetic optimisation of opioid treatment in acute pain therapy
Publisher
An entity responsible for making the resource available
Clinical Pharmacokinetics
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
Subject
The topic of the resource
Humans; Pain; Analgesics; Drug Interactions; Analgesia; Drug Administration Schedule; Administration; Oral; Pain/drug therapy; Infusions; Injections; Intravenous; Dose-Response Relationship; Drug; Subcutaneous; Intramuscular; Patient-Controlled; Postoperative/drug therapy; Substance-Related Disorders; Opioid/pharmacokinetics/pharmacology/therapeutic use; Central Nervous System/drug effects/metabolism
Creator
An entity primarily responsible for making the resource
Upton RN; Semple TJ; Macintyre PE
Description
An account of the resource
Traditionally, opioids have been administered as fixed doses at fixed dose intervals. This approach has been largely ineffective. Patient-controlled analgesia (PCA) and upgraded traditional approaches incorporating flexibility in dose size and dose interval, and titration for an effect in individual patients with the monitoring of pain and sedation scores, can greatly improve the efficacy of opioid administration. Optimising opioid use, therefore, entails optimising the titration process. Opioids have similar pharmacodynamic properties but have widely different kinetic properties. The most important of these is the delay between the blood concentrations of an opioid and its analgesic or other effects, which probably relate to the delay required for blood and brain and spinal cord (CNS) equilibrium. The half-lives of these delays range from approximately 34 minutes for morphine to 1 minute for alfentanil. The titration is influenced by the time needed after an initial dose before it is safe to administer a second dose and the duration of the effects of a single dose, which varies widely between opioids, doses and routes of administration. To compare opioids and routes of administration, we examined the relative CNS concentration profiles of opioids - the CNS concentration expressed as a percentage of its maximum value. The relative onset was the defined as the time the relative CNS concentration first rose to 80% of maximum, while the relative duration was defined as the length of time the concentration was above 80%. For an intravenous bolus dose, the relative onset varies from approximately 1 for alfentanil to 6 minutes for morphine, while their relative durations are approximately 2 and 96 minutes, respectively. Although all of the common opioids, perhaps with the exception of alfentanil, have kinetic and dynamic properties suitable for use in PCA with intravenous bolus doses, the long relative duration of morphine makes it particularly suited to an upgraded traditional approach using staff administered intramuscular or subcutaneous doses. There is a clear kinetic preference for regimens with a rapid onset and short duration (e.g. intravenous PCA) for coping with incident pain. It is shown that, in general, titration is improved by the more frequent administration of smaller doses, but it is important to use additional doses to initially 'load' a patient. The titration of opioids should always be accompanied by the monitoring of pain and sedation scores and ventilation.
1997
Identifier
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<a href="http://doi.org/10.2165/00003088-199733030-00005" target="_blank" rel="noreferrer">10.2165/00003088-199733030-00005</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1997
Administration
Analgesia
Analgesics
Backlog
Central Nervous System/drug effects/metabolism
Clinical Pharmacokinetics
Dose-Response Relationship
Drug
Drug Administration Schedule
Drug Interactions
Humans
Infusions
Injections
Intramuscular
Intravenous
Journal Article
Macintyre PE
Opioid/pharmacokinetics/pharmacology/therapeutic use
Oral
Pain
Pain/drug Therapy
Patient-Controlled
Postoperative/drug therapy
Semple TJ
Subcutaneous
Substance-Related Disorders
Upton RN
-
Dublin Core
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Title
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PedPalASCNet Member Publications
Subject
The topic of the resource
A collection of relevant articles published by one or more of PedPalASCNet's members
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1155/2000/767058" target="_blank" rel="noreferrer">http://doi.org/10.1155/2000/767058</a>
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Title
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Evaluating treatment outcome in an interdisciplinary pediatric pain service
Publisher
An entity responsible for making the resource available
Pain Research And Management
Date
A point or period of time associated with an event in the lifecycle of the resource
2000
Subject
The topic of the resource
Treatment Outcome; Pain; Therapeutics; Children
Creator
An entity primarily responsible for making the resource
Bennett S; Chambers C; Bellows D; Court C; Huntsman E; Montgomery C; Oberlander T; Sheriff M; Siden H
Description
An account of the resource
OBJECTIVE: To provide descriptive data evaluating outcome and treatment satisfaction among former pediatric patients and their parents seen in an interdisciplinary treatment program for complex pain syndromes. DESIGN: Retrospective telephone interview. SETTING: Pediatric academic health care centre. SUBJECTS AND METHODS: A semistructured interview designed for this study was administered by phone with 24 former patients (mean age 15.63 years) and parents, seen over the previous three years in the Complex Pain Consultation Service. Participants provided both qualitative and quantitative information about pre- and post-treatment levels of pain and functioning, achievement of treatment goals and satisfaction with the treatment program. RESULTS: Findings indicated significantly lower frequency and intensity of pain, as rated by patients, when current pain levels were compared with recalled pretreatment levels. As well, improvements were reported in strategies for managing pain and participation in regular activities of daily living. Satisfaction with the team treatment was generally very high, and most felt that their goals were partially to completely met. Child and parent ratings of outcome and satisfaction were consistent. CONCLUSIONS: These descriptive data provide preliminary support for the application of an interdisciplinary model to treating disabling complex pain syndromes in children and youths.
2000
Identifier
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<a href="http://doi.org/10.1155/2000/767058" target="_blank" rel="noreferrer">10.1155/2000/767058</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2000
Backlog
Bellows D
Bennett S
Chambers C
Children
Court C
Huntsman E
Journal Article
Montgomery C
Oberlander T
Pain
Pain Research And Management
Sheriff M
Siden H
Therapeutics
Treatment Outcome
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1111/j.1469-8749.2001.tb00734.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1469-8749.2001.tb00734.x</a>
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Title
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Beliefs about pain among professionals working with children with significant neurologic impairment
Publisher
An entity responsible for making the resource available
Developmental Medicine And Child Neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
Subject
The topic of the resource
Child; Female; Humans; Male; Physician-Patient Relations; Adult; Health Care Surveys; Attitude of Health Personnel; Pain; quality of life; Nervous System Diseases/complications; caregivers; Child welfare
Creator
An entity primarily responsible for making the resource
Oberlander T; O'Donnell ME
Identifier
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<a href="http://doi.org/10.1111/j.1469-8749.2001.tb00734.x" target="_blank" rel="noreferrer">10.1111/j.1469-8749.2001.tb00734.x</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2001
2001
Adult
Attitude Of Health Personnel
Backlog
Caregivers
Child
Child welfare
Developmental Medicine and Child Neurology
Female
Health Care Surveys
Humans
Journal Article
Male
Nervous System Diseases/complications
O'Donnell ME
Oberlander T
Pain
Physician-patient Relations
Quality Of Life
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1111/j.1365-2710.1996.tb00016.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1365-2710.1996.tb00016.x</a>
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Title
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Assessment of nurses' judgement for analgesic requirements of postoperative children
Publisher
An entity responsible for making the resource available
Journal Of Clinical Pharmacy And Therapeutics
Date
A point or period of time associated with an event in the lifecycle of the resource
1996
Subject
The topic of the resource
Child; Female; Humans; Male; Pain; Analgesics; Nursing Assessment; Preschool; Non-Narcotic/administration & dosage/therapeutic use; Acetaminophen/administration & dosage/therapeutic use; Postoperative/drug therapy/psychology; Suppositories; Tonsillectomy
Creator
An entity primarily responsible for making the resource
Romsing J
Description
An account of the resource
Over the last 5-10 years, there has been significant growth in the knowledge and strategies of pain management in children. Investigations are required to discern whether concomitant improvements in clinical practice have occurred. The purpose of this study was to identify the nurses' administration of a traditional analgesic (acetaminophen) with regard to appropriate doses and time intervals. This issue was examined, within 24 h after surgery, in 72 children (aged 3-12 years) scheduled for a tonsillectomy. Acetaminophen suppositories were administered in subtherapeutic doses and at too large time intervals. An average single dose administered represented 87% of the calculated dose. Comparison between the correct dose, which should have been given considering the dose levels of the suppositories available, and the actual dose administered indicates that the nurses tended to round doses down to the next lowest. The average dosage administered per day represented only 76% of the recommended dosage. The prevalence of pain amongst the children was high both before and after analgesics, indicating that acetaminophen in the doses used did not provide any significant measure of pain relief. Current practice is still not optimal. Educating nurses on the effective use of traditional pain therapies may improve paediatric pain management.
1996
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1365-2710.1996.tb00016.x" target="_blank" rel="noreferrer">10.1111/j.1365-2710.1996.tb00016.x</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1996
Acetaminophen/administration & dosage/therapeutic use
Analgesics
Backlog
Child
Female
Humans
Journal Article
Journal Of Clinical Pharmacy And Therapeutics
Male
Non-Narcotic/administration & dosage/therapeutic use
Nursing Assessment
Pain
Postoperative/drug therapy/psychology
Preschool
Romsing J
Suppositories
Tonsillectomy
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1097/01241398-199807000-00018" target="_blank" rel="noreferrer">http://doi.org/10.1097/01241398-199807000-00018</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Epidural analgesia for postoperative pain control in children
Publisher
An entity responsible for making the resource available
Journal Of Pediatric Orthopedics
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
Subject
The topic of the resource
Child; Female; Humans; Male; Pain; Pain Measurement; Prognosis; Treatment Outcome; Drug Therapy; Length of Stay; Analgesia; Anesthetics; adolescent; Preschool; infant; Comparative Study; Dose-Response Relationship; Drug; Fentanyl/administration & dosage; Adjuvants; Postoperative/drug therapy; Combination; Anesthesia/administration & dosage; Bupivacaine/administration & dosage; Epidural/methods; Local/administration & dosage
Creator
An entity primarily responsible for making the resource
Jones MD; Aronsson DD; Harkins JM; Smail DF; Haugh LD
Description
An account of the resource
Ninety-eight continuous postoperative epidurals were administered to 87 children. The patients were divided into two groups: group I included 63 cases in which a 0.0625-0.25% solution of bupivacaine was continuously administered; group II included 35 cases in which a similar solution of bupivacaine mixed with 2-10 micrograms of fentanyl was administered. The dose of the epidural medication was titrated by the anesthesiologist according to the patient's age and anticipated level of postoperative pain. The average pain score for all patients for the first 48 h was 1.43. Supplemental analgesia averaging 0.132 mg intravenous morphine/kg/8 h was required in 49 cases (41 in group I and eight in group II). In group I, the average dose of supplemental analgesia was 0.144 mg intravenous morphine/kg/8 h, whereas in group II, it was only 0.056 mg intravenous morphine/kg/8 h. Continuous epidural analgesia is effective in controlling postoperative pain, and the addition of fentanyl reduces the need for systemic narcotics.
1998
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/01241398-199807000-00018" target="_blank" rel="noreferrer">10.1097/01241398-199807000-00018</a>
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Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1998
Adjuvants
Adolescent
Analgesia
Anesthesia/administration & dosage
Anesthetics
Aronsson DD
Backlog
Bupivacaine/administration & dosage
Child
Combination
Comparative Study
Dose-Response Relationship
Drug
Drug Therapy
Epidural/methods
Female
Fentanyl/administration & dosage
Harkins JM
Haugh LD
Humans
Infant
Jones MD
Journal Article
Journal Of Pediatric Orthopedics
Length Of Stay
Local/administration & dosage
Male
Pain
Pain Measurement
Postoperative/drug therapy
Preschool
Prognosis
Smail DF
Treatment Outcome
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1097/00006254-199404000-00008" target="_blank" rel="noreferrer">http://doi.org/10.1097/00006254-199404000-00008</a>
Dublin Core
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Title
A name given to the resource
Does episiotomy prevent perineal trauma and pelvic floor relaxation?
Publisher
An entity responsible for making the resource available
The Online Journal Of Current Clinical Trials
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
Subject
The topic of the resource
Female; Humans; Pregnancy; Pain; Adult; Time Factors; RDF Project; Coitus; Episiotomy/adverse effects/methods; Labor Stage; Muscle Hypotonia/prevention & control; Parity; Pelvic Floor; Perineum/injuries; Postoperative; Rectum/injuries; Second; Urinary Incontinence/prevention & control; Wounds and Injuries/etiology/prevention & control
Creator
An entity primarily responsible for making the resource
Klein MC; Gauthier RJ; Jorgensen SH; Robbins JM; Kaczorowski J; Johnson B; Corriveau M; Westreich R; Waghorn K; Gelfand MM
Description
An account of the resource
OBJECTIVE: To compare the outcomes of the current practice of liberally or routinely employing episiotomy to prevent perineal tears and pelvic floor relaxation (control group) to a policy of restricting episiotomy use to specific fetal and maternal indications (experimental group). DESIGN: A randomized controlled trial (RCT). SETTING: Three university hospitals in Montreal. SUBJECTS: Seven hundred three low-risk women enrolled at 30 to 34 weeks of gestation were randomized late in labor to the designated trial arm, by parity, and followed up to 3 months postpartum. MAIN OUTCOME MEASURES: Antepartum and postpartum information on perineal trauma and pain, pelvic floor symptoms (urinary incontinence), and sexual activity was collected through the use of standard questionnaires; pelvic floor function was measured by electromyographic (EMG) perineometry. RESULTS: Restricting episiotomy use in primiparous women was associated with similar sutured perineal trauma to the liberal or routine approach. Multiparous women in the restricted episiotomy group more often gave birth with an intact perineum (31% compared with 19%, odds ratio (OR) = 1.85, 95% confidence interval (CI) = 1.09 to 3.16). All but one 3rd/4th-degree perineal tear was associated with median episiotomy (46 of 47 in primiparous women and 6 of 6 among multiparous women). No difference between trial groups was found in postpartum perineal pain, antepartum and 3-month postpartum EMG perineometry, and urinary and pelvic floor symptoms. CONCLUSIONS: We found no evidence that liberal or routine use of episiotomy prevents perineal trauma or pelvic floor relaxation. Virtually all severe perineal trauma was associated with median episiotomy. Restriction of episiotomy use among multiparous women resulted in significantly more intact perineums and less perineal suturing.
1992
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/00006254-199404000-00008" target="_blank" rel="noreferrer">10.1097/00006254-199404000-00008</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1992
Adult
Backlog
Coitus
Corriveau M
Episiotomy/adverse effects/methods
Female
Gauthier RJ
Gelfand MM
Humans
Johnson B
Jorgensen SH
Journal Article
Kaczorowski J
Klein MC
Labor Stage
Muscle Hypotonia/prevention & control
Pain
Parity
Pelvic Floor
Perineum/injuries
Postoperative
Pregnancy
RDF Project
Rectum/injuries
Robbins JM
Second
The Online Journal Of Current Clinical Trials
Time Factors
Urinary Incontinence/prevention & control
Waghorn K
Westreich R
Wounds and Injuries/etiology/prevention & control
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1093/oxfordjournals.bmb.a072500" target="_blank" rel="noreferrer">http://doi.org/10.1093/oxfordjournals.bmb.a072500</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pain management in children
Publisher
An entity responsible for making the resource available
British Medical Bulletin
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
Subject
The topic of the resource
Child; Humans; infant; Pain; Preschool; infant; Newborn; Pain/drug therapy/etiology; Anti-Inflammatory Agents; Neoplasms/complications; Narcotics/therapeutic use; Pain Measurement/methods; Postoperative/drug therapy; Non-Steroidal/therapeutic use
Creator
An entity primarily responsible for making the resource
Goldman A; Lloyd-Thomas AR
Description
An account of the resource
Interest in the management and study of pain in children has increased in recent years. A range of techniques appropriate to children with different developmental levels is now available for the assessment of various aspects of childhood pain. A management plan can be developed depending on the cause of pain and choosing from a range of therapeutic techniques. It should take into account both the physical and psychological aspects of pain. Drugs from the mainstay of treatment of pain with a clear physiological cause. Suitable drugs are now available but inexperience and myths may still result in reluctance to use appropriate strong analgesics in children. Postoperative pain control and the analgesic needs of neonates have been particularly neglected areas. Management can be dramatically improved by increasing staff sensitivity and the use of an integrated programme of drugs, physical techniques and psychological approaches.
1991
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/oxfordjournals.bmb.a072500" target="_blank" rel="noreferrer">10.1093/oxfordjournals.bmb.a072500</a>
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Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1991
Anti-Inflammatory Agents
Backlog
British Medical Bulletin
Child
Goldman A
Humans
Infant
Journal Article
Lloyd-Thomas AR
Narcotics/therapeutic use
Neoplasms/complications
Newborn
Non-Steroidal/therapeutic use
Pain
Pain Measurement/methods
Pain/drug therapy/etiology
Postoperative/drug therapy
Preschool
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1093/bja/72.2.160" target="_blank" rel="noreferrer">http://doi.org/10.1093/bja/72.2.160</a>
Dublin Core
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Title
A name given to the resource
Comparison of different bolus doses of morphine for patient-controlled analgesia in children
Publisher
An entity responsible for making the resource available
British Journal Of Anaesthesia
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
Subject
The topic of the resource
Child; Female; Male; Pain; Pain Measurement; Time Factors; Non-U.S. Gov't; Comparative Study; Nausea/chemically induced; Human; Support; Adolescence; Patient-Controlled; Sleep/drug effects; Vomiting/chemically induced; Appendectomy; Analgesia; Morphine/administration & dosage/adverse effects; Postoperative/prevention & control
Creator
An entity primarily responsible for making the resource
Doyle E; Mottart KJ; Marshall C; Morton NS
Description
An account of the resource
Forty children undergoing appendicectomy were allocated randomly to receive one of two PCA regimens with morphine. Group B10 received bolus doses of 10 micrograms kg-1 and group B20 received bolus doses of 20 micrograms kg-1. In both groups there was a lockout interval of 5 min and a background infusion of 4 micrograms kg-1 h-1. Group B20 self-administered considerably more morphine (P < 0.01) than group B10. There was no difference between the pain scores of the groups at rest. Group B20 had significantly (P < 0.05) smaller pain scores during movement than group B10 and the latter group suffered significantly (P < 0.01) more hypoxaemic episodes than group B20. There were no differences between the groups in the incidence of vomiting, excess sedation or the amount of time spent asleep at night.
1994
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/bja/72.2.160" target="_blank" rel="noreferrer">10.1093/bja/72.2.160</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1994
Adolescence
Analgesia
Appendectomy
Backlog
British Journal Of Anaesthesia
Child
Comparative Study
Doyle E
Female
Human
Journal Article
Male
Marshall C
Morphine/administration & dosage/adverse effects
Morton NS
Mottart KJ
Nausea/chemically induced
Non-U.S. Gov't
Pain
Pain Measurement
Patient-Controlled
Postoperative/prevention & control
Sleep/drug effects
Support
Time Factors
Vomiting/chemically induced
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1093/bja/71.6.818" target="_blank" rel="noreferrer">http://doi.org/10.1093/bja/71.6.818</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Patient-controlled analgesia with low dose background infusions after lower abdominal surgery in children
Publisher
An entity responsible for making the resource available
British Journal Of Anaesthesia
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
Subject
The topic of the resource
Child; Female; Humans; Male; Pain; Analgesia; Drug Administration Schedule; Non-U.S. Gov't; Research Support; Comparative Study; Infusions; Intravenous; Nausea/chemically induced; Morphine/administration & dosage/adverse effects; Postoperative Period; Sleep/drug effects; Vomiting/chemically induced; Postoperative/drug therapy; Appendectomy; Patient-Controlled/adverse effects/methods
Creator
An entity primarily responsible for making the resource
Doyle E; Harper I; Morton NS
Description
An account of the resource
Forty-five children (aged 6-12 yr) undergoing appendicectomy received one of three analgesic regimens using patient-controlled analgesia (PCA) with morphine: no background infusion (BO); background infusion 4 micrograms kg-1 h-1 (B4); background infusion 10 micrograms kg-1 h-1 (B10). Total consumption of morphine was greater in group B10 compared with groups B0 (P < 0.01) and B4 (P < 0.05). There was no significant difference in morphine consumption in groups B0 and B4. All three groups self-administered similar amounts of morphine and there were no significant differences in pain scores or incidence of excessive sedation. Group B4 suffered less hypoxaemia compared with groups B0 (P < 0.01) and B10 (P < 0.001). Group B10 suffered more nausea and vomiting than groups B0 (P < 0.001) and B4 (P < 0.001), but there was no significant difference in the incidence of nausea and vomiting between groups B0 and B4. Groups B4 and B10 spent more time at night asleep than group B0 (P < 0.05). There were no significant differences between the groups in the amount of time spent asleep during the day. Inclusion of a background infusion of morphine 4 micrograms kg-1 h-1 in a PCA regimen for children did not increase the incidence of side effects and was associated with less hypoxaemia and a better sleep pattern than no background infusion.
1993
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/bja/71.6.818" target="_blank" rel="noreferrer">10.1093/bja/71.6.818</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1993
Analgesia
Appendectomy
Backlog
British Journal Of Anaesthesia
Child
Comparative Study
Doyle E
Drug Administration Schedule
Female
Harper I
Humans
Infusions
Intravenous
Journal Article
Male
Morphine/administration & dosage/adverse effects
Morton NS
Nausea/chemically induced
Non-U.S. Gov't
Pain
Patient-Controlled/adverse effects/methods
Postoperative Period
Postoperative/drug therapy
Research Support
Sleep/drug effects
Vomiting/chemically induced
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1093/bja/70.4.414" target="_blank" rel="noreferrer">http://doi.org/10.1093/bja/70.4.414</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Ventilatory effects of morphine, pethidine and methadone in children
Publisher
An entity responsible for making the resource available
British Journal Of Anaesthesia
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
Subject
The topic of the resource
Child; Female; Humans; Male; Pain; Time Factors; Depression; Preschool; Non-U.S. Gov't; Research Support; Oxygen/blood; Postoperative/prevention & control; Respiration/drug effects; Chemical; Meperidine/pharmacology; Methadone/pharmacology; Morphine/pharmacology; Tidal Volume/drug effects
Creator
An entity primarily responsible for making the resource
Hamunen K
Description
An account of the resource
The ventilatory effects of single i.v. doses of morphine 0.1 mg kg-1, pethidine 0.67 mg kg-1 and methadone 0.1 mg kg-1 were compared after ophthalmic surgery in an open, randomized study in 30 children aged 3-8 yr. Ventilatory changes after each drug had distinctive profiles, with appreciable individual variation. Acutely, the decrease in ventilatory frequency was greater with pethidine and methadone than with morphine. The acute decrease in oxygen saturation was greater with methadone and pethidine than with morphine. Methadone produced a greater and longer lasting increase in end-tidal carbon dioxide and greater decrease in end-tidal oxygen than morphine or pethidine. Changes in end-tidal carbon dioxide and oxygen concentrations and saturation were most transient after pethidine and of longest duration after methadone. No child developed apnoea or hypoventilation requiring assistance.
1993
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/bja/70.4.414" target="_blank" rel="noreferrer">10.1093/bja/70.4.414</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1993
Backlog
British Journal Of Anaesthesia
Chemical
Child
Depression
Female
Hamunen K
Humans
Journal Article
Male
Meperidine/pharmacology
Methadone/pharmacology
Morphine/pharmacology
Non-U.S. Gov't
Oxygen/blood
Pain
Postoperative/prevention & control
Preschool
Research Support
Respiration/drug effects
Tidal Volume/drug effects
Time Factors
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1046/j.1460-9592.2001.00659.x" target="_blank" rel="noreferrer">http://doi.org/10.1046/j.1460-9592.2001.00659.x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Postoperative epidural analgesia with bupivacaine and fentanyl: hourly pain assessment in 348 paediatric cases
Publisher
An entity responsible for making the resource available
Paediatric Anaesthesia
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
Subject
The topic of the resource
Child; Female; Humans; infant; Male; Pain; Analgesics; Prospective Studies; Analgesia; Anesthetics; adolescent; Preschool; infant; Newborn; Pain Measurement/drug effects; Opioid/administration & dosage/adverse effects/therapeutic use; Sleep/drug effects; Postoperative/drug therapy; Bupivacaine/administration & dosage/adverse effects/therapeutic use; Epidural/adverse effects; Fentanyl/administration & dosage/adverse effects/therapeutic use; Local/administration & dosage/adverse effects/therapeutic use
Creator
An entity primarily responsible for making the resource
Lejus C; Surbled M; Schwoerer D; Renaudin M; Guillaud C; Berard L; Pinaud M
Description
An account of the resource
BACKGROUND: The objective of this prospective study was the evaluation of the analgesia provided by an epidural infusion of bupivacaine and fentanyl after different types of surgery in children. METHODS: Data were collected from 348 epidural analgesia in 87 children below 2 years of age, in 80 children between 2 and 6 years and 181 above 6 years of age, for a median duration of 43 postoperative hours. Bupivacaine (mean concentration 0.185%) and fentanyl (5 microg.kg-1.day-1) were administered on the surgical ward. RESULTS: Pain control was considered excellent in 86% of the 11 072 pain hourly assessments. Analgesia was found to be better for children older than 2 years, and the overall quality of their night's sleep was better than that of older children. Higher pain scores were noted for Nissen fundoplication surgery and club foot repairs. Early discontinuation rarely occurred, and only because of technical problems with the epidural catheter (4%) or insufficient analgesia (6%). Complications were minor (nausea/vomiting 14%, pruritus 0.6%, urinary retention 17%) and easily reversed. CONCLUSIONS: This combination of bupivacaine-fentanyl provides safe analgesia after major surgery in children with frequent clinical monitoring. Regular pain assessments of intensity and duration are useful to improve the quality of postoperative analgesia.
2001
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1046/j.1460-9592.2001.00659.x" target="_blank" rel="noreferrer">10.1046/j.1460-9592.2001.00659.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2001
Adolescent
Analgesia
Analgesics
Anesthetics
Backlog
Berard L
Bupivacaine/administration & dosage/adverse effects/therapeutic use
Child
Epidural/adverse effects
Female
Fentanyl/administration & dosage/adverse effects/therapeutic use
Guillaud C
Humans
Infant
Journal Article
Lejus C
Local/administration & dosage/adverse effects/therapeutic use
Male
Newborn
Opioid/administration & dosage/adverse effects/therapeutic use
Paediatric Anaesthesia
Pain
Pain Measurement/drug effects
Pinaud M
Postoperative/drug therapy
Preschool
Prospective Studies
Renaudin M
Schwoerer D
Sleep/drug effects
Surbled M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1046/j.1460-9592.1999.00384.x" target="_blank" rel="noreferrer">http://doi.org/10.1046/j.1460-9592.1999.00384.x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Efficacy and complications of morphine infusions in postoperative paediatric patients
Publisher
An entity responsible for making the resource available
Paediatric Anaesthesia
Date
A point or period of time associated with an event in the lifecycle of the resource
1999
Subject
The topic of the resource
Child; Female; Humans; Male; Pain; Analgesics; Follow-Up Studies; Confidence Intervals; Incidence; Acute Disease; adolescent; Preschool; infant; retrospective studies; Infusions; Intravenous; Opioid/administration & dosage/adverse effects/therapeutic use; Morphine/administration & dosage/adverse effects/therapeutic use; Postoperative/prevention & control; Respiration/drug effects; Akathisia; Analgesia/nursing; Anesthesia Recovery Period; Anoxemia/chemically induced; Arousal/drug effects; Drug-Induced/etiology; Postoperative Nausea and Vomiting/chemically induced; Pruritus/chemically induced; Urinary Retention/chemically induced
Creator
An entity primarily responsible for making the resource
Esmail Z; Montgomery C; Courtrn C; Hamilton D; Kestle J
Description
An account of the resource
The aim of the study was to evaluate the efficacy and the incidence of clinically significant adverse drug reactions (ADRs) in paediatric patients receiving continuous intravenous morphine infusions for acute postoperative pain. Definitions were established for ADRs and data were collected in an immediately retrospective fashion for a maximum of 72 h in 110 patients >/=5 three months of age (0.3-16.7 years) receiving morphine infusions and admitted to a general ward over a three month convenience sampling period. Inadequate analgesia occurred in 65.5% of patients during the first 24 h of therapy and occurred most frequently in patients with infusion rates of 20 microg.kg-1.h-1 or less. Nausea/vomiting was the most commonly experienced ADR (42.5%). The incidence of respiratory depression was 0% (95% CI=0-3.3%). Other ADRs included: urinary retention (13.5%), pruritus (12.7%), dysphoria (7.3%), hypoxaemia (4.5%), discontinuation of morphine for treatment of an ADR (3.6%), and difficulty in arousal (0.9%). The most common ADRs associated with morphine infusions were inadequate analgesia (in the first 24 h) and nausea/vomiting. There were no cases of respiratory depression. Methods of avoiding initial inadequate analgesia and treating nausea and vomiting associated with morphine infusions are needed.
1999
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1046/j.1460-9592.1999.00384.x" target="_blank" rel="noreferrer">10.1046/j.1460-9592.1999.00384.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1999
Acute Disease
Adolescent
Akathisia
Analgesia/nursing
Analgesics
Anesthesia Recovery Period
Anoxemia/chemically induced
Arousal/drug effects
Backlog
Child
Confidence Intervals
Courtrn C
Drug-Induced/etiology
Esmail Z
Female
Follow-up Studies
Hamilton D
Humans
Incidence
Infant
Infusions
Intravenous
Journal Article
Kestle J
Male
Montgomery C
Morphine/administration & dosage/adverse effects/therapeutic use
Opioid/administration & dosage/adverse effects/therapeutic use
Paediatric Anaesthesia
Pain
Postoperative Nausea and Vomiting/chemically induced
Postoperative/prevention & control
Preschool
Pruritus/chemically induced
Respiration/drug effects
Retrospective Studies
Urinary Retention/chemically induced
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1037//0022-006x.59.3.431" target="_blank" rel="noreferrer">http://doi.org/10.1037//0022-006x.59.3.431</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Control beliefs, coping efforts, and adjustment to chronic pain
Publisher
An entity responsible for making the resource available
Journal Of Consulting And Clinical Psychology
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
Subject
The topic of the resource
Female; Humans; Male; Pain; Pain Measurement; Chronic disease; Middle Aged; Sick Role; Internal-External Control; Adaptation; Psychological
Creator
An entity primarily responsible for making the resource
Jensen MP; Karoly P
Description
An account of the resource
This study examined factors hypothesized to influence adaptation to chronic pain in 118 patients who were interviewed to gauge adjustment (psychological functioning, medical services utilization, and activity level) and several widely discussed predictors of adjustment. Control appraisals and the practice of ignoring pain, using coping self-statements, and increasing activities were positively related to psychological functioning. Control appraisals and the practice of diverting attention, ignoring pain, and using coping self-statements also yielded a positive relation to activity level, but only for those patients reporting relatively low levels of pain severity. None of the predictors were related to medical services utilization. Future research is needed to replicate these findings and help clarify when appraisals and coping strategies are most productive among patients with chronic pain.
1991-06
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1037//0022-006x.59.3.431" target="_blank" rel="noreferrer">10.1037//0022-006x.59.3.431</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1991
Adaptation
Backlog
Chronic Disease
Female
Humans
Internal-External Control
Jensen MP
Journal Article
Journal Of Consulting And Clinical Psychology
Karoly P
Male
Middle Aged
Pain
Pain Measurement
Psychological
Sick Role
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s1089-9472(97)80051-2" target="_blank" rel="noreferrer">http://doi.org/10.1016/s1089-9472(97)80051-2</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pain management: a quality improvement project
Publisher
An entity responsible for making the resource available
Journal Of Perianesthesia Nursing
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
Subject
The topic of the resource
Humans; Pain; Program Evaluation; RDF Project; Postoperative/nursing/therapy; Quality of Health Care/organization & administration; Recovery Room/standards
Creator
An entity primarily responsible for making the resource
Rittenmeyer H; Dolezal D; Vogel E
Description
An account of the resource
Pain management in the PACU is vital to patient care and favorable outcomes. Understanding all aspects of pain management is essential when caring for surgical patients. Most PACUs have quality improvement (QI) and/or risk management projects that involve pain management. This article discusses a QI project on the management of pain and the effect it had on nursing practice. The QI committee developed an improvement program that identified a patient care need and changed practice to improve patient care. The project began with the question "Are we accurately assessing patients' pain, or is the pain assessed only what the nurse perceives?" The QI data collected indicated that 100% of patients were discharged with adequate pain relief. The question was answered by following the recommendations of the Joint Commission on Accreditation of Healthcare Organizations for the QI process, in addition to using a model for linking outcomes to care processes developed by Windle and Houston.
1997
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s1089-9472(97)80051-2" target="_blank" rel="noreferrer">10.1016/s1089-9472(97)80051-2</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1997
Backlog
Dolezal D
Humans
Journal Article
Journal Of Perianesthesia Nursing
Pain
Postoperative/nursing/therapy
Program Evaluation
Quality of Health Care/organization & administration
RDF Project
Recovery Room/standards
Rittenmeyer H
Vogel E
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s1072-7515(01)01091-2" target="_blank" rel="noreferrer">http://doi.org/10.1016/s1072-7515(01)01091-2</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Chronic pain management and the surgeon: barriers and opportunities
Publisher
An entity responsible for making the resource available
Journal Of The American College Of Surgeons
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
Subject
The topic of the resource
Humans; Palliative Care; Pain; Analgesics; Physician's Role; patient care team; Chronic disease; Surgery; Opioid/administration & dosage/therapeutic use; Pain/therapy; Intractable/drug therapy; Neoplasms/surgery; Postoperative/drug therapy
Creator
An entity primarily responsible for making the resource
Lee KF; Ray JB; Dunn GP
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s1072-7515(01)01091-2" target="_blank" rel="noreferrer">10.1016/s1072-7515(01)01091-2</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
Description
An account of the resource
2001
2001
Analgesics
Backlog
Chronic Disease
Dunn GP
Humans
Intractable/drug therapy
Journal Article
Journal Of The American College Of Surgeons
Lee KF
Neoplasms/surgery
Opioid/administration & dosage/therapeutic use
Pain
Pain/therapy
Palliative Care
Patient Care Team
Physician's Role
Postoperative/drug therapy
Ray JB
Surgery
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s0885-3924(99)00048-2" target="_blank" rel="noreferrer">http://doi.org/10.1016/s0885-3924(99)00048-2</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Methadone response in advanced cancer patients with pain followed at home
Publisher
An entity responsible for making the resource available
Journal Of Pain And Symptom Management
Date
A point or period of time associated with an event in the lifecycle of the resource
1999
Subject
The topic of the resource
Female; Humans; Male; Pain; Pain Measurement; Analgesics; Prospective Studies; Middle Aged; Sex Factors; Neoplasms/physiopathology; Methadone/administration & dosage/adverse effects/therapeutic use; Opioid/administration & dosage/adverse effects/therapeutic use; home care services; Intractable/drug therapy
Creator
An entity primarily responsible for making the resource
Mercadante S; Casuccio A; Agnello A; Barresi L
Description
An account of the resource
Concerns about the safety of therapy with methadone, which may arise because of its pharmacokinetic characteristics and inappropriate dosing, may deter clinicians from using this drug, especially in elderly patients. Experience is accumulating that the drug may be used safely and successfully if low doses are given initially and care is taken in the titration of the dose against the pain. A prospective study was carried out in a consecutive sample of 45 advanced cancer patients followed at home, who had never received other strong opioids for their pain. Patients were treated with an oral liquid preparation of methadone, which was administered 2-3 times daily, according to need. Doses were kept as low as possible and were titrated to achieve acceptable analgesia with minimal adverse effects. The methadone starting dose (MSD) at referral, the maximum dose of methadone (MMD), the days of methadone treatment, the use of other nonopioid analgesics, symptoms associated with methadone therapy, pain intensity, and pain mechanism were recorded. Methadone escalation index percentage (MEI%) and methadone escalation index in mg (MEI mg) were calculated from these parameters. No correlations between age and gender, and MSD, MMD, days on methadone, VAS and symptoms were found. No significant differences were found in pain mechanisms, age, and other parameters, including methadone-related symptoms. Treatment of pain with methadone provides important support to patients with cancer followed at home and the risks are low with individually titrated doses, even in older patients or in the presence of a neuropathic pain mechanism.
1999
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0885-3924(99)00048-2" target="_blank" rel="noreferrer">10.1016/s0885-3924(99)00048-2</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1999
Agnello A
Analgesics
Backlog
Barresi L
Casuccio A
Female
home care services
Humans
Intractable/drug therapy
Journal Article
Journal of Pain and Symptom Management
Male
Mercadante S
Methadone/administration & dosage/adverse effects/therapeutic use
Middle Aged
Neoplasms/physiopathology
Opioid/administration & dosage/adverse effects/therapeutic use
Pain
Pain Measurement
Prospective Studies
Sex Factors
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s0885-3924(98)00366-2" target="_blank" rel="noreferrer">http://doi.org/10.1016/s0885-3924(98)00366-2</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pain medication during terminal care of children with cancer
Publisher
An entity responsible for making the resource available
Journal Of Pain And Symptom Management
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
Subject
The topic of the resource
Palliative Care; Terminal Care; Analgesics; Pain; Morphine; Analgesia; Narcotics; Palliative treatment; Children; Administration; Oral; Neoplasms; Opioid
Creator
An entity primarily responsible for making the resource
Sirkia K; Hovi L; Pouttu J; Saarinen-Pihkala U
Description
An account of the resource
The purpose of this study was to evaluate the need for pain medication and the adequacy or inadequacy of the analgesia achieved, in children with cancer who died while in terminal care. Of the 100 pediatric patients with cancer treated at the Children's Hospital, University of Helsinki, Finland, who died during 1987-1992, 70 died while in terminal care. The underlying diseases were leukemia (N=25), solid tumors (N=24), and brain tumors (N=21). Of these children, 60% were treated at home, 29% at hospital, and 11% at both. The assessment of pain during terminal care was retrospective and included analysis of the patients' records and a structured interview of the two parents separately. In total, 62 children (89%) received regular pain medication, with a mean duration of 17 days in children with leukemia, 58 days in those with solid tumors, and 66 days in those with brain tumors. Medication was usually started with anti-inflammatory drugs, then changed to oral opioids when deemed necessary, and finally to parenteral opioids. Parenteral morphine was administered to 40 children, to 30 as a continuous infusion through a central venous line. The dose of morphine was 0.8 mg/kg/day at the start and was increased to 4.9 (range, 0.2-55) mg/kg/day. Of the 62 children who received regular pain medication, the majority (81%) had adequate analgesia. In 19%, analgesia had been suboptimal. In conclusion, the vast majority of children with cancer need regular pain medication while in terminal care. This can be administered adequately at home, even if continuous intravenous infusions are required.
1998
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0885-3924(98)00366-2" target="_blank" rel="noreferrer">10.1016/s0885-3924(98)00366-2</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1998
Administration
Analgesia
Analgesics
Backlog
Children
Hovi L
Journal Article
Journal of Pain and Symptom Management
Morphine
Narcotics
Neoplasms
Opioid
Oral
Pain
Palliative Care
Palliative Treatment
Pouttu J
Saarinen-Pihkala U
Sirkia K
Terminal Care
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s0885-3924(97)00075-4" target="_blank" rel="noreferrer">http://doi.org/10.1016/s0885-3924(97)00075-4</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
A randomized, controlled trial of intravenous clodronate in patients with metastatic bone disease and pain
Publisher
An entity responsible for making the resource available
Journal Of Pain And Symptom Management
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
Subject
The topic of the resource
Female; Humans; Male; Pain; Adult; Analgesics; Aged; Middle Aged; Treatment Outcome; Analysis of Variance; Chi-Square Distribution; Cross-Over Studies; 80 and over; Comparative Study; Injections; Intravenous; Dose-Response Relationship; Drug; Clodronate; Pain Measurement/drug effects; Clodronic Acid/administration & dosage; Non-Narcotic/administration & dosage; Intractable/drug therapy/etiology; Bone Neoplasms/complications/secondary
Creator
An entity primarily responsible for making the resource
Ernst DS; Brasher P; Hagen N; Paterson AH; MacDonald RN; Bruera E
Description
An account of the resource
To evaluate the effectiveness of intravenous clodronate in ameliorating refractory bone pain in patients with metastatic bone disease, 60 patients with established osseous metastases and persistent bone pain were randomized to receive either clodronate (600 mg or 1500 mg in 500 mL of normal saline) or 500 mL of saline as placebo. After 2 weeks, the patients were crossed over to receive the alternate treatment. After another 2 weeks, each patient and investigator made a blinded choice. Daily visual analogue scales (VAS) and analgesic diaries were recorded throughout the study period. Forty-six patients were evaluable (77%). A treatment x period interaction was identified in the VAS and daily morphine equivalent dose (DMED) scores. First period analysis of the VAS scores for general pain, pain at rest, and pain upon movement demonstrated an average reduction of 13, 14, and 24 mm, respectively, from baseline, but were not significantly different from changes following placebo. The average change in DMED was -6.4 (SE = 2.9) following clodronate and was +24.6 (SE = 14.9) following placebo (p = 0.03). In the blinded choice of which agent resulted in improvement in pain, 26 (57%) patients chose clodronate, 12 (26%) chose placebo, and eight (17%) had no preference (p = 0.0021). For the investigators who also made a blinded selection, clodronate was chosen in 30 (65%) patients, placebo in ten (22%) patients, and no difference was apparent in six (13%) (p < 0.0001). Intravenous clodronate appeared to have analgesic effect in patients with refractory bone pain due to metastatic bone disease. The optimal dose and duration of effect require further evaluation, particularly in patients with stable disease and persistent bone pain.
1997
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0885-3924(97)00075-4" target="_blank" rel="noreferrer">10.1016/s0885-3924(97)00075-4</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1997
80 And Over
Adult
Aged
Analgesics
Analysis of Variance
Backlog
Bone Neoplasms/complications/secondary
Brasher P
Bruera E
Chi-Square Distribution
Clodronate
Clodronic Acid/administration & dosage
Comparative Study
Cross-Over Studies
Dose-Response Relationship
Drug
Ernst DS
Female
Hagen N
Humans
Injections
Intractable/drug therapy/etiology
Intravenous
Journal Article
Journal of Pain and Symptom Management
MacDonald RN
Male
Middle Aged
Non-Narcotic/administration & dosage
Pain
Pain Measurement/drug effects
Paterson AH
Treatment Outcome
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s0304-3959(99)00267-5" target="_blank" rel="noreferrer">http://doi.org/10.1016/s0304-3959(99)00267-5</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Quantitative estimation of rare adverse events which follow a biological progression: a new model applied to chronic NSAID use
Publisher
An entity responsible for making the resource available
Pain
Date
A point or period of time associated with an event in the lifecycle of the resource
2000
Subject
The topic of the resource
Humans; Cohort Studies; Death; Disease Progression; Risk Assessment; Non-U.S. Gov't; Research Support; Models; Statistical; Anti-Inflammatory Agents; Databases; Factual; Digestive System; Endoscopy; Gastrointestinal Hemorrhage/chemically induced/mortality; Non-Steroidal/adverse effects; Peptic Ulcer Perforation/chemically induced/mortality
Creator
An entity primarily responsible for making the resource
Tramer MR; Moore RA; Reynolds DJ; McQuay HJ
Description
An account of the resource
Randomised controlled trials (RCTs) alone are unlikely to provide reliable estimates of the incidence of rare events because of their limited size. Cohort, case control, and other observational studies have large numbers but are vulnerable to various kinds of bias. Wanting to estimate the risk of death from bleeding or perforated gastroduodenal ulcers with chronic usage of non-steroidal anti-inflammatory drugs (NSAIDs) with greater precision, we developed a model to quantify the frequency of rare adverse events which follow a biological progression. The model combined data from both RCTs and observational studies. We searched systematically for any report of chronic (>/=2 months) use of NSAIDs which gave information on gastroduodenal ulcer, bleed or perforation, death due to these complications, or progression from one level of harm to the next. Fifteen RCTs (19364 patients exposed to NSAIDs for 2-60 months), three cohort studies (215076 patients redeeming a NSAID prescription over a 3-12 month period), six case-control studies (2957 cases) and 20 case series (7406), and case reports (4447) were analysed. In RCTs the incidence of bleeding or perforation in 6822 patients exposed to NSAIDs was 0.69%; two deaths occurred. Of 11040 patients with bleeding or perforation with or without NSAID exposure across all reports, 6-16% (average 12%) died; the risk was lowest in RCTs and highest in case reports. Death from bleeding or perforation in all controls not exposed to NSAIDs occurred in 18 out of 849489 (0.002%). From these numbers we calculated the number-needed-to-treat for one patient to die due to gastroduodenal complications with chronic (>/=2 months) NSAIDs as 1/((0.69x inverted question mark6-16%, average 12% inverted question mark)-0.002%))=909-2500 (average 1220). On average 1 in 1200 patients taking NSAIDs for at least 2 months will die from gastroduodenal complications who would not have died had they not taken NSAIDs. This extrapolates to about 2000 deaths each year in the UK.
2000
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0304-3959(99)00267-5" target="_blank" rel="noreferrer">10.1016/s0304-3959(99)00267-5</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2000
Anti-Inflammatory Agents
Backlog
Cohort Studies
Databases
Death
Digestive System
Disease Progression
Endoscopy
Factual
Gastrointestinal Hemorrhage/chemically induced/mortality
Humans
Journal Article
McQuay HJ
Models
Moore RA
Non-Steroidal/adverse effects
Non-U.S. Gov't
Pain
Peptic Ulcer Perforation/chemically induced/mortality
Research Support
Reynolds DJ
Risk Assessment
statistical
Tramer MR
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s0304-3959(99)00154-2" target="_blank" rel="noreferrer">http://doi.org/10.1016/s0304-3959(99)00154-2</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Efficacy of pharmacological treatments of neuropathic pain: An update and effect related to mechanism of drug action
Publisher
An entity responsible for making the resource available
Pain
Date
A point or period of time associated with an event in the lifecycle of the resource
1999
Subject
The topic of the resource
Humans; Animals; Antidepressive Agents; Non-U.S. Gov't; Research Support; Pain/drug therapy/etiology; Randomized Controlled Trials; Narcotics/therapeutic use; Analgesics/therapeutic use; Carbamazepine/therapeutic use; Diabetic Neuropathies/complications; N-Methylaspartate/antagonists & inhibitors/therapeutic use; Neuralgia/drug therapy; Polyneuropathies/complications; Serotonin Uptake Inhibitors/therapeutic use; Tricyclic/therapeutic use
Creator
An entity primarily responsible for making the resource
Sindrup SH; Jensen TS
Description
An account of the resource
Tricyclic antidepressants and carbamazepine have become the mainstay in the treatment of neuropathic pain. Within the last decade, controlled trials have shown that numerous other drugs relieve such pain. We identified all placebo-controlled trials and calculated numbers needed to treat (NNT) to obtain one patient with more than 50% pain relief in order to compare the efficacy with the current treatments, and to search for relations between mechanism of pain and drug action. In diabetic neuropathy, NNT was 1.4 in a study with optimal doses of the tricyclic antidepressant imipramine as compared to 2.4 in other studies on tricyclics. The NNT was 6.7 for selective serotonin reuptake inhibitors, 3.3 for carbamazepine, 10.0 for mexiletine, 3.7 for gabapentin, 1.9 for dextromethorphan, 3.4 for tramadol and levodopa and 5.9 for capsaicin. In postherpetic neuralgia, the NNT was 2.3 for tricyclics, 3.2 for gabapentin, 2.5 for oxycodone and 5.3 for capsaicin, whereas dextromethorphan was inactive. In peripheral nerve injury, NNT was 2.5 for tricyclics and 3.5 for capsaicin. In central pain, NNT was 2.5 for tricyclics and 3. 4 for carbamazepine, whereas selective serotonin reuptake inhibitors, mexiletine and dextromethorphan were inactive. There were no clear relations between mechanism of action of the drugs and the effect in distinct pain conditions or for single drug classes and different pain conditions. It is concluded that tricyclic antidepressants in optimal doses appear to be the most efficient treatment of neuropathic pain, but some of the other treatments may be important due to their better tolerability. Relations between drug and pain mechanisms may be elucidated by studies focusing on specific neuropathic pain phenomena such as pain paroxysms and touch-evoked pain.
1999
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0304-3959(99)00154-2" target="_blank" rel="noreferrer">10.1016/s0304-3959(99)00154-2</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1999
Analgesics/therapeutic use
Animals
Antidepressive Agents
Backlog
Carbamazepine/therapeutic use
Diabetic Neuropathies/complications
Humans
Jensen TS
Journal Article
N-Methylaspartate/antagonists & inhibitors/therapeutic use
Narcotics/therapeutic use
Neuralgia/drug therapy
Non-U.S. Gov't
Pain
Pain/drug therapy/etiology
Polyneuropathies/complications
Randomized Controlled Trials
Research Support
Serotonin Uptake Inhibitors/therapeutic use
Sindrup SH
Tricyclic/therapeutic use
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/s0304-3959(99)00117-7" target="_blank" rel="noreferrer">http://doi.org/10.1016/s0304-3959(99)00117-7</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
N of 1 randomised controlled trials of oral ketamine in patients with chronic pain
Publisher
An entity responsible for making the resource available
Pain
Date
A point or period of time associated with an event in the lifecycle of the resource
1999
Subject
The topic of the resource
Female; Humans; Male; Administration; Oral; Analgesics/administration & dosage/therapeutic use; Pain/drug therapy/etiology/physiopathology; Ketamine/administration & dosage/therapeutic use; Placebos
Creator
An entity primarily responsible for making the resource
Haines DR; Gaines SP
Description
An account of the resource
Anecdotal reports suggest that the general anaesthetic drug ketamine, taken orally in low doses, can give rise to some extra analgesia in patients with refractory neuropathic pain. This study was designed to determine the proportion of patients with chronic neuropathic pain responding to oral ketamine, and then to separate the true treatment effect from non-specific effects by means of an n of 1 randomised controlled trial. Twenty-one patients gave informed consent and completed daily pain diaries and continued on their usual treatments (drug and non-drug) for the duration of the study. After a 'baseline' week, oral ketamine was taken once a day for 1 week. The dose of 20 mg was increased each day until an analgesic effect was noticed or adverse effects occurred, or until a maximum of 100 mg was reached. Those patients responding to oral ketamine were then entered into the n of 1 randomised trial which consisted of three treatment/placebo week pairs. Twelve patients did not progress to the n of 1 trial because of no benefit and/or intolerable adverse effects (dizziness, drowsiness etc.). Nine patients completed the n of 1 trial; there was no difference between the ketamine and placebo weeks in six patients; one patient demonstrated effective analgesia with ketamine, but it was of short duration and marred by unpleasant adverse effects; two patients showed some evidence of a beneficial response to ketamine, and continued with the oral ketamine after the trial. We conclude that oral ketamine only gave rise to an extra analgesic response in three out of 21 patients with chronic neuropathic pain (14%). Adverse effects limited the use of the drug in almost half of the patients. The n of 1 trial was useful in demonstrating no true therapeutic effect for the ketamine in two thirds of the patients progressing to that part of the trial.
1999
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0304-3959(99)00117-7" target="_blank" rel="noreferrer">10.1016/s0304-3959(99)00117-7</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1999
Administration
Analgesics/administration & dosage/therapeutic use
Backlog
Female
Gaines SP
Haines DR
Humans
Journal Article
Ketamine/administration & dosage/therapeutic use
Male
Oral
Pain
Pain/drug therapy/etiology/physiopathology
Placebos