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Text
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Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1038/nm908" target="_blank" rel="noreferrer">http://doi.org/10.1038/nm908</a>
Dublin Core
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Title
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Attacking pain at its source: new perspectives on opioids
Publisher
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Nature Medicine
Date
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2003
Subject
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Humans; Analgesics; Animals; Non-U.S. Gov't; Research Support; Drug Tolerance; Receptors; Ligands; Afferent/metabolism; Cell Movement; Neurons; Opioid Peptides/metabolism/therapeutic use; Opioid/genetics/metabolism; Opioid/metabolism/therapeutic use; Pain/drug therapy/metabolism/therapy; Signal Transduction/physiology
Creator
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Stein C; Schafer M; Machelska H
Description
An account of the resource
The treatment of severe pain with opioids has thus far been limited by their unwanted central side effects. Recent research promises new approaches, including opioid analgesics acting outside the central nervous system, targeting of opioid peptide-containing immune cells to peripheral damaged tissue, and gene transfer to enhance opioid production at sites of injury.
2003
Identifier
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<a href="http://doi.org/10.1038/nm908" target="_blank" rel="noreferrer">10.1038/nm908</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2003
Afferent/metabolism
Analgesics
Animals
Backlog
Cell Movement
Drug Tolerance
Humans
Journal Article
Ligands
Machelska H
Nature Medicine
Neurons
Non-U.S. Gov't
Opioid Peptides/metabolism/therapeutic use
Opioid/genetics/metabolism
Opioid/metabolism/therapeutic use
Pain/drug therapy/metabolism/therapy
Receptors
Research Support
Schafer M
Signal Transduction/physiology
Stein C