A Longitudinal Follow-Up Study of Affect in Children and Adults With Cornelia de Lange Syndrome
Rehabilitation; behavior; Education & Educational Research; Cornelia de Lange syndrome; behavioral-phenotype; mental-retardation; affect; autistic; behavioral phenotypes; delange-syndrome; follow-up; fragile-x-syndrome; genetic syndromes; genotype-phenotype correlations; longitudinal; pervasive developmental disorders; spectrum disorders; williams-syndrome; behavioral problems; De Lange syndrome; Cri-du-chat; trajectory; characteristics; mood; interest; pleasure
Studies of individuals with Cornelia de Lange syndrome (CdLS) have described changes in mood and behavior with age, although no empirical or longitudinal studies have been conducted. Caregivers of individuals with CdLS (N = 67), cri du chat syndrome (CdCS; N = 42), and Fragile X syndrome (FXS; N = 142) completed the Mood, Interest and Pleasure Questionnaire (MIPQ) at Time 1 and 2 years later (Time 2). Scores on the MIPQ were significantly lower in the CdLS group compared with the CdCS and FXS groups at Time 1 and Time 2. Lower MIPQ scores were characteristic of older adolescents (> 15 years) and adults with CdLS. However, there were no significant differences in MIPQ scores between Time 1 and Time 2. Age and insistence on sameness predicted MIPQ scores in CdLS.
Nelson L; Moss J; Oliver C
American Journal on Intellectual and Developmental Disabilities
2014
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1352/1944-7558-119.3.235" target="_blank" rel="noreferrer noopener">10.1352/1944-7558-119.3.235</a>
Depression and anxiety symptoms in children and adolescents with autism spectrum disorders without intellectual disability
Prevalence; Comorbidity; Depression; Anxiety; Children; Adolescents; Autism; DEVELOPMENTAL; PSYCHIATRY; Psychology; ASPERGER-SYNDROME; At Risk Persons; Depression/psychology; DIAGNOSTIC INTERVIEW; Education; FRIENDSHIP; Intelligence Quotient; parent; People; PERVASIVE DEVELOPMENTAL DISORDERS; PSYCHIATRIC-DISORDERS; Rehabilitation; Special; Symptoms (Individual Disorders); VERSION
Recent studies have shown that rates of depression and anxiety symptoms are elevated among individuals with autism spectrum disorders (ASDs) of various ages and IQs and that depression/anxiety symptoms are associated with higher IQ and fewer ASD symptoms. In this study which examined correlates of depression and anxiety symptoms in the full school-age range of children and adolescents (age 6-18) with ASDs and IQs greater than or equal to 70 (n = 95), we also observed elevated rates of depression/anxiety symptoms, but we did not find higher IQ or fewer ASD symptoms among individuals with ASDs and depression or anxiety symptoms. These findings indicate an increased risk for depression/anxiety symptoms in children and adolescents with ASDs without intellectual disability, regardless of age, IQ, or ASD symptoms. (Contains 2 tables and 1 figure.)
Strang JF; Kenworthy L; Daniolos P; Case L; Wills MC; Martin A; Wallace GL
Research In Autism Spectrum Disorders
2012
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Journal Article
<a href="http://doi.org/10.1016/j.rasd.2011.06.015" target="_blank" rel="noreferrer">10.1016/j.rasd.2011.06.015</a>