1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
November 2017 List
Notes
<p>1440-1754<br />Joffre, Christelle<br />Lesage, Fabrice<br />Bustarret, Olivier<br />Hubert, Philippe<br />Oualha, Mehdi<br />Journal Article<br />Australia<br />J Paediatr Child Health. 2016 Jun;52(6):595-9. doi: 10.1111/jpc.13214.</p>
URL Address
<a href="http://onlinelibrary.wiley.com/doi/10.1111/jpc.13214/abstract" target="_blank" rel="noreferrer">http://onlinelibrary.wiley.com/doi/10.1111/jpc.13214/abstract</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Children with Down syndrome: Clinical course and mortality-associated factors in a French medical paediatric intensive care unit
Publisher
An entity responsible for making the resource available
Journal Of Paediatrics And Child Health
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
Hospitalization; Intensive Care Units Pediatric; Adolescent; Child; Child Preschool; Critical Illness/ Mortality; Critically Ill Children; Down Syndrome; Down Syndrome/ Complications/ Mortality; Female; Hospital Mortality; Humans; Infant; Male; Mortality; Retrospective Studies
Creator
An entity primarily responsible for making the resource
Joffre C; Lesage F; Bustarret O; Hubert P; Oualha M
Description
An account of the resource
AIM: To investigate clinical course and mortality-associated factors in children with Down syndrome (DS) managed in a medical paediatric intensive care unit. METHODS: A single-centre, retrospective study conducted between 2001 and 2010 in DS children aged 1 month to 16 years. RESULTS: Sixty-six patients with a median age of 24 months (1-192) and a male/female ratio of 1.5 were analysed. Patients presented with history of congenital heart disease (n = 52, 78.8%), mechanical ventilation (n = 40, 60.6%) and chronic upper airway obstruction (n = 10, 15.1%). The primary reason for admission was respiratory failure (n = 56, 84.8%). Pulmonary arterial hypertension (PAH) (n = 19, 28.8%), acute respiratory distress syndrome (ARDS) (n = 18, 27.2%) and sepsis (n = 14, 21.2%) were observed during their clinical course. Twenty-six patients died (39.4%). Mortality-associated factors included the following: (i) baseline characteristics: history of mechanical ventilation, chronic upper airway obstruction and congenital heart disease; (ii) clinical course during paediatric intensive care unit stay: sepsis, catecholamine support, ARDS, PAH and nosocomial infection. In multivariate logistic analysis, history of mechanical ventilation, ARDS and PAH remained independently associated with death. CONCLUSIONS: The mortality rate in critically ill DS children admitted for medical reasons is high and is predominantly associated with respiratory conditions.
Identifier
An unambiguous reference to the resource within a given context
<a href="https://doi.org/10.1111/jpc.13214" target="_blank" rel="noreferrer">10.1111/jpc.13214</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
Adolescent
Bustarret O
Child
Child Preschool
Critical Illness/ Mortality
Critically Ill Children
Down Syndrome
Down Syndrome/ Complications/ Mortality
Female
Hospital Mortality
Hospitalization
Hubert P
Humans
Infant
Intensive Care Units Pediatric
Joffre C
Journal of Paediatrics and Child Health
Lesage F
Male
Mortality
November 2017 List
Oualha M
Retrospective Studies