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Text
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URL Address
<a href="http://doi.org/10.1007/bf00350961" target="_blank" rel="noreferrer">http://doi.org/10.1007/bf00350961</a>
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Title
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Radiological manifestations of bisphosphonate treatment with APD in a child suffering from osteogenesis imperfecta
Publisher
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Skeletal Radiology
Date
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1987
Subject
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Child; Female; Humans; Follow-Up Studies; Clodronate; Diphosphonates/therapeutic use; Osteogenesis Imperfecta/drug therapy/radiography
Creator
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Devogelaer JP; Malghem J; Maldague B; Nagant de Deuxchaisnes C
Description
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A 12-year-old female suffering from osteogenesis imperfecta (OI) was treated with 3-amino-1-hydroxypropylidene-1,1-bisphosphonate (APD) orally, 250 mg daily, for periods of 2 months, alternating with periods of 2 months of abstinence. Total duration of therapy was 1 year. Radiological and clinical improvement was striking. Furthermore, X-rays of the bones showed large, parallel radio-opaque striae, corresponding exactly to the periods of therapy. These were present in all metaphyses.
1987
Identifier
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<a href="http://doi.org/10.1007/bf00350961" target="_blank" rel="noreferrer">10.1007/bf00350961</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
1987
Backlog
Child
Clodronate
Devogelaer JP
Diphosphonates/therapeutic use
Female
Follow-up Studies
Humans
Journal Article
Maldague B
Malghem J
Nagant de Deuxchaisnes C
Osteogenesis Imperfecta/drug therapy/radiography
Skeletal Radiology