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Tags: Opioid/immunology/therapeutic use

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Influence of pain treatment by epidural fentanyl and bupivacaine on homing of opioid-containing leukocytes to surgical wounds

Endogenous opioids released from leukocytes extravasating into injured tissue can interact with peripheral opioid receptors to inhibit nociception. Animal studies have shown that the homing of opioid-producing leukocytes to the injured site is…

Tags: 2007, Adjuvants, Aged, Analgesia, Analgesics, Anesthesia, Anesthesia/immunology/pharmacology, Anesthetics, Backlog, beta-Endorphin/drug effects/immunology/metabolism, Biomarkers of Pain, Brain, Behavior, And Immunity, Bupivacaine/immunology/therapeutic use, Cell Movement/drug effects/immunology, Enkephalin, Epidural, Female, Fentanyl/immunology/therapeutic use, Heurich M, Humans, Journal Article, Kopf A, Lenzner M, Leukocytes/drug effects/immunology/metabolism, Local/immunology/therapeutic use, Longitudinal Studies, Male, Methionine/drug effects/immunology/metabolism, Middle Aged, Morciniec P, Mousa SA, Nociceptors/drug effects/immunology, Opioid/immunology/therapeutic use, Pain, Patient-Controlled, Pirinitramide/therapeutic use, Postganglionic/drug effects/immunology, Postoperative/immunology/prevention & control, Stein C, Subcutaneous Tissue/immunology, Sympathetic Fibers, Welte M, Wound Healing/drug effects/immunology

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