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40
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2066846" target="_blank" rel="noreferrer">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2066846</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Comparison of morphine and methadone for prevention of postoperative pain in 3- to 7-year-old children
Publisher
An entity responsible for making the resource available
Journal Of Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
Subject
The topic of the resource
Child; Female; Male; Pain; Pain Measurement; Prospective Studies; Analysis of Variance; Double-Blind Method; Preschool; Non-U.S. Gov't; Comparative Study; Drug Evaluation; Human; Support; Postoperative/prevention & control; algorithms; Intraoperative Care; Methadone/adverse effects/pharmacokinetics/therapeutic use; Morphine/adverse effects/therapeutic use
Creator
An entity primarily responsible for making the resource
Berde CB; Beyer JE; Bournaki MC; Levin CR; Sethna NF
Description
An account of the resource
A randomized, double-blind, prospective study was performed to determine the effects of perioperative administration of morphine or methadone on postoperative analgesic requirements and pain scores in 35 children aged 3 to 7 years undergoing major surgery. After a standardized induction of anesthesia, methadone or morphine, 0.2 mg/kg, was blindly administered, and supplemental doses were titrated to achieve comfort in the recovery room. Pain was assessed during the next 36 hours with a combination of validated behavioral and self-report measures. Patients in the methadone group required fewer supplemental opioid analgesic drugs during the next 36 hours, and reported lower pain scores. No patient had prolonged emergence from anesthesia, and no patient required naloxone or postoperative ventilatory assistance. No major adverse events occurred. We conclude that perioperative intravenous administration of methadone is an effective, inexpensive, and technologically simple means for providing prolonged analgesia for children after surgery.
1991
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1991
algorithms
Analysis of Variance
Backlog
Berde CB
Beyer JE
Bournaki MC
Child
Comparative Study
Double-Blind Method
Drug Evaluation
Female
Human
Intraoperative Care
Journal Article
Journal of Pediatrics
Levin CR
Male
Methadone/adverse effects/pharmacokinetics/therapeutic use
Morphine/adverse effects/therapeutic use
Non-U.S. Gov't
Pain
Pain Measurement
Postoperative/prevention & control
Preschool
Prospective Studies
Sethna NF
Support
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1080/j354v16n01_04" target="_blank" rel="noreferrer">http://doi.org/10.1080/j354v16n01_04</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Clinical use of methadone
Publisher
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Journal of Pain and Palliative Care Pharmacotherapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
Subject
The topic of the resource
Humans; Analgesics; Drug Interactions; Therapeutic Equivalency; Half-Life; Drug Administration Schedule; Pain/drug therapy; Receptors; Biological Availability; Opioid/adverse effects/pharmacokinetics/therapeutic use; Dosage Forms; Kidney Diseases/metabolism; Liver Diseases/metabolism; Methadone/adverse effects/pharmacokinetics/therapeutic use; Opioid-Related Disorders/drug therapy; Opioid/agonists; Substance Withdrawal Syndrome/etiology
Creator
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Layson-Wolf C; Goode JV; Small RE
Description
An account of the resource
Methadone hydrochloride is a mu-opioid agonist that has been used for the treatment of pain and for the management and maintenance of opioid withdrawal for over 50 years. Several characteristics make methadone a useful drug. However, these same characteristics and wide interpatient variability can make methadone difficult to use safely. A MEDLINE search was conducted on publications between January 1996 and May 2001 to identify literature relevant to this subject. Those publications were reviewed, and from them, other literature was identified and reviewed. Published studies demonstrate methadone's efficacy in pain management and in opioid withdrawal. However, interpatient variability in pharmacokinetic variables of methadone produces difficulties in developing guidelines for methadone use. Clinicians should not be deterred from use of this drug which has been shown to benefit patients in both pain management and methadone maintenance, but an individualized patient approach must be taken to use methadone safely.
2002
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1080/j354v16n01_04" target="_blank" rel="noreferrer">10.1080/j354v16n01_04</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2002
Analgesics
Backlog
Biological Availability
Dosage Forms
Drug Administration Schedule
Drug Interactions
Goode JV
Half-Life
Humans
Journal Article
Journal of Pain and Palliative Care Pharmacotherapy
Kidney Diseases/metabolism
Layson-Wolf C
Liver Diseases/metabolism
Methadone/adverse effects/pharmacokinetics/therapeutic use
Opioid-Related Disorders/drug therapy
Opioid/adverse effects/pharmacokinetics/therapeutic use
Opioid/agonists
Pain/drug Therapy
Receptors
Small RE
Substance Withdrawal Syndrome/etiology
Therapeutic Equivalency