1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1007/bf00598955" target="_blank" rel="noreferrer">http://doi.org/10.1007/bf00598955</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Tay-Sachs disease: Progression of changes on neuroimaging in four cases. Publisher An entity responsible for making the resource available Neuroradiology Date A point or period of time associated with an event in the lifecycle of the resource 1992 Subject The topic of the resource Child; Humans; Male; Follow-Up Studies; Longitudinal Studies; Magnetic Resonance Imaging; Preschool; infant; Brain Diseases; Emission-Computed; Tomography; Brain/pathology; Atrophy; X-Ray Computed; Demyelinating Diseases/diagnosis/pathology; Metabolic/diagnosis/pathology; Tay-Sachs Disease/diagnosis/pathology Creator An entity primarily responsible for making the resource Fukumizu M; Yoshikawa H; Takashima S; Sakuragawa N; Kurokawa T Description An account of the resource The neuroradiological findings in four patients with Tay-Sachs disease are described in three phases of the clinical course. The basal ganglia and cerebral white matter show low density on computed tomography and high signal intensity on T2-weighted magnetic resonance imaging in the initial phase. The caudate nuclei are characteristically enlarged and protrude into the lateral ventricles in the first and second phases. The cerebral white matter shows low density on the CT which varies in extent from the second to third phases, and the whole brain becomes atrophic in the last phase. Thus, central nervous system involvement in the disease may begin in basal ganglia as well as in cerebral white matter. 1992 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1007/bf00598955" target="_blank" rel="noreferrer">10.1007/bf00598955</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 1992 Atrophy Backlog Brain Diseases Brain/pathology Child Demyelinating Diseases/diagnosis/pathology Emission-Computed Follow-up Studies Fukumizu M Humans Infant Journal Article Kurokawa T Longitudinal Studies Magnetic Resonance Imaging Male Metabolic/diagnosis/pathology Neuroradiology Preschool Sakuragawa N Takashima S Tay-Sachs Disease/diagnosis/pathology Tomography X-Ray Computed Yoshikawa H