1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1016/j.jclinane.2006.07.003" target="_blank" rel="noreferrer">http://doi.org/10.1016/j.jclinane.2006.07.003</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource No change in serum melatonin, or plasma beta-endorphin levels after sevoflurane anesthesia Publisher An entity responsible for making the resource available Journal Of Clinical Anesthiology Date A point or period of time associated with an event in the lifecycle of the resource 2007 Subject The topic of the resource Female; Humans; Cohort Studies; Adult; Prospective Studies; Middle Aged; Time Factors; Reference Values; Anesthetics; Anesthesia; beta-Endorphin/blood/drug effects; Blood Pressure/drug effects; Dilatation and Curettage/methods; Electroencephalography/methods; General/methods; Heart Rate/drug effects; Inhalation/administration & dosage/pharmacology; Melatonin/blood; Methyl Ethers/administration & dosage/pharmacology; Oximetry/methods; Oxygen/blood; Postoperative Period; Sleep/drug effects Creator An entity primarily responsible for making the resource Fassoulaki A; Kostopanagiotou G; Meletiou P; Chasiakos D; Markantonis S Description An account of the resource STUDY OBJECTIVE: To investigate the effect of sevoflurane as single anesthetic on melatonin and beta-endorphin plasma levels during the first 24 hours postoperatively. DESIGN: Prospective, open-cohort study. SETTING: University hospital. PATIENTS: 13 ASA physical status I and II, adults, scheduled for dilatation and curettage of the uterus, and 13 healthy volunteers. INTERVENTIONS: Patients received general anesthesia with sevoflurane. MEASUREMENTS: Melatonin and beta-endorphin plasma levels were determined before anesthesia, immediately after, and two, 4, 8, and 24 hours after the end of anesthesia. Melatonin and beta-endorphin were also measured in 13 healthy subjects (controls) not undergoing anesthesia at similar times during the day. Systolic and diastolic blood pressure, heart rate, bispectral index, and oxygen saturation via pulse oximeter (SpO(2)) were recorded before and after anesthesia. Quality of sleep postoperatively was also assessed. MAIN RESULTS: Melatonin levels (pg/mL) in the patients and controls were 8.2 +/- 7.9 versus 15.2 +/- 15.0 before anesthesia and 7.7 +/- 7.9 versus 11.1 +/- 7.0, 6.5 +/- 6.1 versus 15.6 +/- 16.3, and 19.5 +/- 17.9 versus 23.7 +/- 23.3 at the end of anesthesia and 4 and 24 hours after the end of anesthesia, respectively (P = 0.057). At the same time points, beta-endorphin plasma levels (pmol/L) in patients and controls were 5.2 +/- 2.0 versus 4.0 +/- 2.3, 5.4 +/- 3.3 versus 3.9 +/- 2.5, 4.9 +/- 1.2 versus 4.4 +/- 1.7, and 3.7 +/- 2.6 versus 4.2 +/- 1.8, respectively (P= 0.285). The quality of sleep assessed clinically was not altered. CONCLUSION: Sevoflurane as a single anesthetic for minor gynecological procedures did not influence significantly melatonin or beta-endorphin plasma levels. Sleep quality assessed clinically was not influenced. 2007 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.jclinane.2006.07.003" target="_blank" rel="noreferrer">10.1016/j.jclinane.2006.07.003</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 2007 Adult Anesthesia Anesthetics Backlog beta-Endorphin/blood/drug effects Blood Pressure/drug effects Chasiakos D Cohort Studies Dilatation and Curettage/methods Electroencephalography/methods Fassoulaki A Female General/methods Heart Rate/drug effects Humans Inhalation/administration & dosage/pharmacology Journal Article Journal Of Clinical Anesthiology Kostopanagiotou G Markantonis S Melatonin/blood Meletiou P Methyl Ethers/administration & dosage/pharmacology Middle Aged Oximetry/methods Oxygen/blood Postoperative Period Prospective Studies Reference Values Sleep/drug effects Time Factors