1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1001/jama.295.1.50" target="_blank" rel="noreferrer">http://doi.org/10.1001/jama.295.1.50</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource First documented rhythm and clinical outcome from in-hospital cardiac arrest among children and adults Publisher An entity responsible for making the resource available Jama Date A point or period of time associated with an event in the lifecycle of the resource 2006 Subject The topic of the resource Child; Female; Hospitalization; Humans; Male; Adult; Hospital Mortality; Prospective Studies; Aged; Middle Aged; Survival Analysis; adolescent; Preschool; 80 and over; infant; cardiopulmonary resuscitation; Heart Arrest/mortality/physiopathology/therapy; Tachycardia; Ventricular Fibrillation/physiopathology; Ventricular/physiopathology Creator An entity primarily responsible for making the resource Nadkarni VM; Larkin GL; Peberdy MA; Carey SM; Kaye W; Mancini ME; Nichol G; Lane-Truitt T; Potts J; Ornato JP; Berg RA; National Registry of Cardiopulmonary Resuscitation Investigators Description An account of the resource CONTEXT: Cardiac arrests in adults are often due to ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT), which are associated with better outcomes than asystole or pulseless electrical activity (PEA). Cardiac arrests in children are typically asystole or PEA. OBJECTIVE: To test the hypothesis that children have relatively fewer in-hospital cardiac arrests associated with VF or pulseless VT compared with adults and, therefore, worse survival outcomes. DESIGN, SETTING, AND PATIENTS: A prospective observational study from a multicenter registry (National Registry of Cardiopulmonary Resuscitation) of cardiac arrests in 253 US and Canadian hospitals between January 1, 2000, and March 30, 2004. A total of 36,902 adults (> or =18 years) and 880 children (<18 years) with pulseless cardiac arrests requiring chest compressions, defibrillation, or both were assessed. Cardiac arrests occurring in the delivery department, neonatal intensive care unit, and in the out-of-hospital setting were excluded. MAIN OUTCOME MEASURE: Survival to hospital discharge. RESULTS: The rate of survival to hospital discharge following pulseless cardiac arrest was higher in children than adults (27% [236/880] vs 18% [6485/36,902]; adjusted odds ratio [OR], 2.29; 95% confidence interval [CI], 1.95-2.68). Of these survivors, 65% (154/236) of children and 73% (4737/6485) of adults had good neurological outcome. The prevalence of VF or pulseless VT as the first documented pulseless rhythm was 14% (120/880) in children and 23% (8361/36,902) in adults (OR, 0.54; 95% CI, 0.44-0.65; P<.001). The prevalence of asystole was 40% (350) in children and 35% (13 024) in adults (OR, 1.20; 95% CI, 1.10-1.40; P = .006), whereas the prevalence of PEA was 24% (213) in children and 32% (11,963) in adults (OR, 0.67; 95% CI, 0.57-0.78; P<.001). After adjustment for differences in preexisting conditions, interventions in place at time of arrest, witnessed and/or monitored status, time to defibrillation of VF or pulseless VT, intensive care unit location of arrest, and duration of cardiopulmonary resuscitation, only first documented pulseless arrest rhythm remained significantly associated with differential survival to discharge (24% [135/563] in children vs 11% [2719/24,987] in adults with asystole and PEA; adjusted OR, 2.73; 95% CI, 2.23-3.32). CONCLUSIONS: In this multicenter registry of in-hospital cardiac arrest, the first documented pulseless arrest rhythm was typically asystole or PEA in both children and adults. Because of better survival after asystole and PEA, children had better outcomes than adults despite fewer cardiac arrests due to VF or pulseless VT. 2006 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1001/jama.295.1.50" target="_blank" rel="noreferrer">10.1001/jama.295.1.50</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 2006 80 And Over Adolescent Adult Aged Backlog Berg RA Cardiopulmonary Resuscitation Carey SM Child Female Heart Arrest/mortality/physiopathology/therapy Hospital Mortality Hospitalization Humans Infant JAMA Journal Article Kaye W Lane-Truitt T Larkin GL Male Mancini ME Middle Aged Nadkarni VM National Registry of Cardiopulmonary Resuscitation Investigators Nichol G Ornato JP Peberdy MA Potts J Preschool Prospective Studies Survival Analysis Tachycardia Ventricular Fibrillation/physiopathology Ventricular/physiopathology