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Text
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<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11087278" target="_blank" rel="noreferrer">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11087278</a>
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Title
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Effect of severity of disability on survival in north east England cerebral palsy cohort
Publisher
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Archives Of Disease In Childhood
Date
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2000
Subject
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Female; infant; Male; Survival Rate; Cohort Studies; Prognosis; Risk Factors; Birth Weight; Non-U.S. Gov't; Newborn; cause of death; Human; Life Expectancy; Sex Distribution; Life Style; Support; England/epidemiology; Disability Evaluation; Cerebral Palsy/mortality
Creator
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Hutton JL; Colver AF; Mackie PC
Description
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AIMS: To investigate the effect of motor and cognitive disabilities on the survival of people on the North of England Collaborative Cerebral Palsy Survey, and compare this with other published results. METHODS: The cerebral palsy cohort consists of 1960-1990 births in Northumberland, Newcastle, and North Tyneside health districts. Survival and cause of death were analysed in relation to data on birth, disabilities, and a unique measure of the impact of disability. RESULTS: Disability strongly influences survival. More than a third of those with a severe disability die before age 30. Fewer than a third of deaths are attributed to cerebral palsy on death certificates. Of those with severe cognitive disability, 63% live to age 35 (58% with severe ambulatory disability and 53% with severe manual disability), whereas at least 98% without severe disabilities live to age 35. The Lifestyle Assessment Score (LAS) allows a finer categorisation of impact of disability, and is strongly associated with survival: a ten point increase in LAS is associated with a doubling of the hazard rate. People who had LAS of at least 70, and had survived to age 5 have a 39% chance of dying before age 35. CONCLUSIONS: The majority of people with cerebral palsy attain adulthood. There appears to be more variation in survival rates associated with severe disability between regions of England, than between north east England, British Columbia, and California. Instantaneous risks of dying vary widely between England and California. This variation is not obviously attributable to differing rates of severe disability.
2000
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2000
Archives of Disease in Childhood
Backlog
Birth Weight
Cause Of Death
Cerebral Palsy/mortality
Cohort Studies
Colver AF
Disability Evaluation
England/epidemiology
Female
Human
Hutton JL
Infant
Journal Article
Life Expectancy
Life Style
Mackie PC
Male
Newborn
Non-U.S. Gov't
Prognosis
Risk Factors
Sex Distribution
Support
Survival Rate