1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1203/00006450-199804001-00475" target="_blank" rel="noreferrer">http://doi.org/10.1203/00006450-199804001-00475</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bisphosphonates for treatment of childhood hypercalcemia Publisher An entity responsible for making the resource available Pediatrics Date A point or period of time associated with an event in the lifecycle of the resource 1998 Subject The topic of the resource Child; Female; Humans; Leukemia; adolescent; Preschool; Clodronate; Diphosphonates/therapeutic use; Acute; Lymphocytic; Calcium/blood; Hypercalcemia/drug therapy/etiology; Immobilization/adverse effects; L1/complications Creator An entity primarily responsible for making the resource Lteif AN; Zimmerman D Description An account of the resource Most clinicians only have a limited experience in treating childhood hypercalcemia with bisphosphonates. We report our experience in the use of intravenous and oral bisphosphonates in a 5-year-old with hypercalcemia secondary to acute lymphocytic leukemia, a 16-year-old with immobilization hypercalcemia, and a 14-year-old with chronic hypercalcemia of unknown cause. Single infusions of 0.5 mg/kg and 1 mg/kg of intravenous pamidronate were administered over 4 hours. No adverse reactions were observed except for hypocalcemia. A dose between 10 and 20 mg of oral alendronate was successfully used to maintain normocalcemia in the patient with chronic hypercalcemia. In our experience, the administration of bisphosphonates has enabled us to achieve normocalcemia in all cases, and in all cases there were no significant side effects. Long-term potential side effects from their use in children during the active phase of growth remain unknown. 1998 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1203/00006450-199804001-00475" target="_blank" rel="noreferrer">10.1203/00006450-199804001-00475</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 1998 Acute Adolescent Backlog Calcium/blood Child Clodronate Diphosphonates/therapeutic use Female Humans Hypercalcemia/drug therapy/etiology Immobilization/adverse effects Journal Article L1/complications Leukemia Lteif AN Lymphocytic Pediatrics Preschool Zimmerman D