1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1080/j354v16n01_04" target="_blank" rel="noreferrer">http://doi.org/10.1080/j354v16n01_04</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinical use of methadone Publisher An entity responsible for making the resource available Journal of Pain and Palliative Care Pharmacotherapy Date A point or period of time associated with an event in the lifecycle of the resource 2002 Subject The topic of the resource Humans; Analgesics; Drug Interactions; Therapeutic Equivalency; Half-Life; Drug Administration Schedule; Pain/drug therapy; Receptors; Biological Availability; Opioid/adverse effects/pharmacokinetics/therapeutic use; Dosage Forms; Kidney Diseases/metabolism; Liver Diseases/metabolism; Methadone/adverse effects/pharmacokinetics/therapeutic use; Opioid-Related Disorders/drug therapy; Opioid/agonists; Substance Withdrawal Syndrome/etiology Creator An entity primarily responsible for making the resource Layson-Wolf C; Goode JV; Small RE Description An account of the resource Methadone hydrochloride is a mu-opioid agonist that has been used for the treatment of pain and for the management and maintenance of opioid withdrawal for over 50 years. Several characteristics make methadone a useful drug. However, these same characteristics and wide interpatient variability can make methadone difficult to use safely. A MEDLINE search was conducted on publications between January 1996 and May 2001 to identify literature relevant to this subject. Those publications were reviewed, and from them, other literature was identified and reviewed. Published studies demonstrate methadone's efficacy in pain management and in opioid withdrawal. However, interpatient variability in pharmacokinetic variables of methadone produces difficulties in developing guidelines for methadone use. Clinicians should not be deterred from use of this drug which has been shown to benefit patients in both pain management and methadone maintenance, but an individualized patient approach must be taken to use methadone safely. 2002 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1080/j354v16n01_04" target="_blank" rel="noreferrer">10.1080/j354v16n01_04</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 2002 Analgesics Backlog Biological Availability Dosage Forms Drug Administration Schedule Drug Interactions Goode JV Half-Life Humans Journal Article Journal of Pain and Palliative Care Pharmacotherapy Kidney Diseases/metabolism Layson-Wolf C Liver Diseases/metabolism Methadone/adverse effects/pharmacokinetics/therapeutic use Opioid-Related Disorders/drug therapy Opioid/adverse effects/pharmacokinetics/therapeutic use Opioid/agonists Pain/drug Therapy Receptors Small RE Substance Withdrawal Syndrome/etiology Therapeutic Equivalency