1
40
2
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1055/s-0028-1091644" target="_blank" rel="noreferrer noopener">http://doi.org/10.1055/s-0028-1091644</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The effect of L 5 hydroxytryptophan on self mutilation in Lesch Nyhan disease: a negative report
Publisher
An entity responsible for making the resource available
Neuropadiatrie
Date
A point or period of time associated with an event in the lifecycle of the resource
1976
Subject
The topic of the resource
automutilation; self-mutilation; child; clinical study; clinical trial; controlled study; drug therapy; human; Lesch Nyhan syndrome; major clinical study; therapy; L-5-hydroxyl-tryptophan; carbidopa; placebo; pharmacologic intervention; behavioral problems
Creator
An entity primarily responsible for making the resource
Anderson L T; Herrmann L; Dancis J
Description
An account of the resource
Four patients with Lesch Nyhan disease were treated with L 5 hydroxytryptophan, alone, or in combination with carbidopa, and their effect on self mutilatory behavior was compared to that observed during periods in which placebo was administered. Observation periods were carefully standardized because of the ease with which patient observer interactions can influence the behavior of the Lesch Nyhan patient. The dosage level was sufficient to produce undesirable side effects (diarrhea and vomiting). No effect on self mutilation was observed under test conditions in the hospital or in the natural environment of the home. These results contrast with previous beneficial effects reported by others.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1055/s-0028-1091644" target="_blank" rel="noreferrer noopener">10.1055/s-0028-1091644</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
1976
Anderson L T
automutilation
behavioral problems
carbidopa
Child
Clinical Study
Clinical Trial
Controlled Study
Dancis J
Drug Therapy
Herrmann L
Human
L-5-hydroxyl-tryptophan
Lesch Nyhan syndrome
Major Clinical Study
Neuropadiatrie
pharmacologic intervention
PLACEBO
self-mutilation
Therapy
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1038/265461a0" target="_blank" rel="noreferrer noopener">http://doi.org/10.1038/265461a0</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Punishment learning and self mutilation in Lesch Nyhan disease
Publisher
An entity responsible for making the resource available
Nature
Date
A point or period of time associated with an event in the lifecycle of the resource
1977
Subject
The topic of the resource
automutilation; aversion; child; etiology; learning; Lesch Nyhan syndrome; punishment; reinforcement therapy; behavioral problems; psychological intervention; aversive stimulation electric shock; positive reinforcement; time-out; self-injury; self-mutilation
Creator
An entity primarily responsible for making the resource
Anderson L; Dancis J; Alpert M; Herrmann L
Description
An account of the resource
The self injurious behavior of five male children with Lesch Nyhan disease was studied during three learning paradigms: punishment, positive reinforcement and time out from reinforcement following an attempt at self injury. Punishment of self injury by contingent electric finger shock failed to suppress this behavior but positive reinforcement of non self injury and time out procedures were effective. The results stress the importance of environmental factors in the development and control of self injurious behavior, and suggest the presence of an unusual harmful defect which may be related to the specific enzyme deficiency in Lesch Nyhan disease.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1038/265461a0" target="_blank" rel="noreferrer noopener">10.1038/265461a0</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
1977
Alpert M
Anderson L
automutilation
aversion
aversive stimulation electric shock
behavioral problems
Child
Dancis J
etiology
Herrmann L
Learning
Lesch Nyhan syndrome
Nature
positive reinforcement
psychological intervention
punishment
reinforcement therapy
self-injury
self-mutilation
time-out