1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1002/pbc.24977" target="_blank" rel="noreferrer">http://doi.org/10.1002/pbc.24977</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Brachytherapy in children with rhabdomyosarcomas of the nasolabial fold Publisher An entity responsible for making the resource available Pediatric Blood & Cancer Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource adolescent; Child; Female; Humans; infant; Male; retrospective studies; Survival Rate; Rhabdomyosarcoma; Skin Neoplasms; Preschool; Newborn; Disease-Free Survival; Brachytherapy; Facial Neoplasms; Nasolabial Fold Creator An entity primarily responsible for making the resource Mazeron R; Oberlin O; Dumas I; Kolb F; Goulart J; Rivin E; Haie-Méder C Description An account of the resource BACKGROUND: Rhabdomyosarcomas (RMS) of the nasolabial fold can be difficult to manage surgically due to functional and cosmetic limitations. Therefore, brachytherapy (BT) has been proposed to improve local control while limiting the volume of irradiation as well as the extent of the surgical excision. MATERIALS AND METHODS: Sixteen pediatric cases with RMS of the nasolabial fold treated from 1971 to 2005 were retrospectively reviewed. RESULTS: Median follow-up was 4.4 years (1.7-33). Half of the patients were male and their age at diagnosis ranged from 4 months to 13.5 years. Histological subtypes included 10 embryonal and 6 alveolar RMS. Initial treatment consisted of induction multi-agent chemotherapy in all cases. In 12 patients, BT was combined with local excision (4 complete resections, 1 with macroscopic residual disease, and 7 with microscopic disease). Low dose-rate brachytherapy was performed in all cases according to the Paris system, using plastic catheters implanted per-operatively. The doses delivered ranged from 50 to 70 Gy, depending on chemotherapy response, and surgical margin status. 10 patients relapsed: 4 local, 6 regional, and 2 metastatic failures were reported. The median time to relapse was 6.5 months. At the time of analysis eight patients were alive and four had died. Four cases, under palliative care at last check-up, were lost to follow-up. CONCLUSION: BT provided an acceptable local control rate, but the poor regional control of these cases may suggest a need for more aggressive management of cervical regional lymph node regions in RMS of the nasolabial fold. 2014-07 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1002/pbc.24977" target="_blank" rel="noreferrer">10.1002/pbc.24977</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 2014 Adolescent Backlog Brachytherapy Child Disease-Free Survival Dumas I Facial Neoplasms Female Goulart J Haie-Méder C Humans Infant Journal Article Kolb F Male Mazeron R Nasolabial Fold Newborn Oberlin O Pediatric Blood & Cancer Preschool Retrospective Studies Rhabdomyosarcoma Rivin E Skin Neoplasms Survival Rate