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<a href="http://doi.org/10.1002/ana.10996" target="_blank" rel="noreferrer">http://doi.org/10.1002/ana.10996</a>
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Title
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The effect of spinal cord stimulation in patients with chronic reflex sympathetic dystrophy: two years' follow-up of the randomized controlled trial
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Annals Of Neurology
Date
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2004
Subject
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Chronic disease; Reflex sympathetic dystrophy; Spinal cord
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Kemler MA; De Vet HCW; Barendse GAM; Van Den Wildenberg FAJM; Van Kleef M
Description
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Chronic reflex sympathetic dystrophy is a painful, disabling disorder for which no treatment with proven effect is available. We performed a randomized trial in a 2 to 1 ratio of patients, in which 36 patients were treated with spinal cord stimulation and physical therapy (SCS+PT), and 18 patients received solely PT. Twenty-four SCS+PT patients were given a permanent spinal cord stimulation system after successful test stimulation; the remaining 12 patients received no permanent system. We assessed pain intensity, global perceived effect, functional status, and health-related qualify of life. Patients were examined before randomization, before implantation, and also at 1, 3, 6, 12, and 24 months thereafter. At 2 years, three patients were excluded from the analysis. The intention-to-treat analysis showed improvements in the SCS+PT group concerning pain intensity (-2.1 vs 0.0cm; p < 0.001) and global perceived effect (43% vs 6% "much improved"; p = 0.001). There was no clinically important improvement of functional status. Health-related quality of life improved only in the group receiving spinal cord stimulation. After careful selection and successful test stimulation, spinal cord stimulation results in a long-term pain reduction and health-related quality of life improvement in chronic reflex sympathetic dystrophy.
2004
Identifier
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<a href="http://doi.org/10.1002/ana.10996" target="_blank" rel="noreferrer">10.1002/ana.10996</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2004
Annals Of Neurology
Backlog
Barendse GAM
Chronic Disease
De Vet HCW
Journal Article
Kemler MA
Reflex sympathetic dystrophy
Spinal cord
Van Den Wildenberg FAJM
Van Kleef M