1 40 1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource September 2024 List Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month September List 2024 URL Address <a href="http://doi.org/10.1097/PCC.0000000000003579" target="_blank" rel="noreferrer noopener"> http://doi.org/10.1097/PCC.0000000000003579</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Trajectories in Intensity of Medical Interventions at the End of Life: Clustering Analysis in a Pediatric, Single-Center Retrospective Cohort, 2013-2021 Publisher An entity responsible for making the resource available Pediatric Critical Care Medicine Date A point or period of time associated with an event in the lifecycle of the resource 2024 Subject The topic of the resource palliative therapy; major clinical study; retrospective study; cohort analysis; health care personnel; time of death; human; article; child; female; male; terminal care; consultation; resuscitation; intensive care unit; drug therapy; aggression; coronary care unit; special situation for pharmacovigilance; cluster analysis; hospital mortality; organ transplantation Creator An entity primarily responsible for making the resource Liesse KM; Malladi L; Dinh TC; Wesp BM; Kam BN; Turturice BA; Pyke-Grimm KA; Char DS; Hollander SA Description An account of the resource Objective: Pediatric deaths often occur within hospitals and involve balancing aggressive treatment with minimization of suffering. This study first investigated associations between clinical/demographic features and the level of intensity of various therapies these patients undergo at the end of life (EOL). Second, the work used these data to develop a new, broader spectrum for classifying pediatric EOL trajectories. Design: Retrospective, single-center study, 2013-2021. Setting: Four hundred sixty-one bed tertiary, stand-alone children's hospital with 112 ICU beds. Patients: Patients of age 0-26 years old at the time of death. Interventions: None. Measurements and main results: Of 1111 included patients, 85.7% died in-hospital. Patients who died outside the hospital were older. Among the 952 in-hospital deaths, most occurred in ICUs (89.5%). Clustering analysis was used to distinguish EOL trajectories based on the presence of intensive therapies and/or an active resuscitation attempt at the EOL. We identified five simplified categories: 1) death during active resuscitation, 2) controlled withdrawal of life-sustaining technology, 3) natural progression to death despite maximal therapy, 4) discontinuation of nonsustaining therapies, and 5) withholding/noninitiation of future therapies. Patients with recent surgical procedures, a history of organ transplantation, or admission to the Cardiovascular ICU had more intense therapies at EOL than those who received palliative care consultations, had known genetic conditions, or were of older age. Conclusions: In this retrospective study of pediatric EOL trajectories based on the intensity of technology and/or resuscitation discontinued at the EOL, we have identified associations between these trajectories and patient characteristics. Further research is needed to investigate the impact of these trajectories on families, patients, and healthcare providers. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1097/PCC.0000000000003579" target="_blank" rel="noreferrer noopener">10.1097/PCC.0000000000003579</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). 2024 Aggression Article Char DS Child Cluster Analysis Cohort Analysis Consultation coronary care unit Dinh TC Drug Therapy Female Health Care Personnel Hollander SA Hospital Mortality Human Intensive Care Unit Kam BN Liesse KM Major Clinical Study Male Malladi L Organ Transplantation Palliative Therapy Pediatric Critical Care Medicine Pyke-Grimm KA Resuscitation Retrospective Study September List 2024 special situation for pharmacovigilance Terminal Care time of death Turturice BA Wesp BM