Subject
Female; Humans; infant; Male; Adult; Disease Progression; Longitudinal Studies; Genetic Counseling; Newborn; Age of Onset; Cholesterol/metabolism; Esterification; Fibroblasts/pathology; Foam Cells/pathology; Histiocytes/pathology; Intelligence Tests; Jaundice; Neonatal/etiology; Nervous System Diseases/etiology; Niemann-Pick Diseases/diagnosis/genetics/pathology/physiopathology/therapy; Splenomegaly/etiology