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40
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1159/000181525" target="_blank" rel="noreferrer">http://doi.org/10.1159/000181525</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Plasma beta-endorphin during fasting in man
Publisher
An entity responsible for making the resource available
Hormone Research
Date
A point or period of time associated with an event in the lifecycle of the resource
1990
Subject
The topic of the resource
Female; Humans; Male; Adult; adolescent; Body Weight; beta-Endorphin/blood; Homeostasis/drug effects; Creatinine/blood; Hydrocortisone/blood; Blood Urea Nitrogen; Cholesterol/blood; Fasting/metabolism; Uric Acid/blood
Creator
An entity primarily responsible for making the resource
Komaki G; Tamai H; Sumioki H; Mori T; Kobayashi N; Mori K; Mori S; Nakagawa T
Description
An account of the resource
To identify the effects of acute starvation on endogenous opioids in man, plasma beta-endorphin (beta-EP) was measured in 17 patients before, during and after fasting. Patients were assigned a posteriori into two groups: group A, comprised of 11 patients able to tolerate 5-7 days of fasting, and group B, comprised of 6 patients able to tolerate 10 days of fasting. Changes in plasma beta-EP, serum cortisol, circulating nutritional markers, and their relative levels were assessed on the 5th and 10th days of fasting, and on the 5th and 10th days of the refeeding period. Beta-EP had increased by the 5th day (group A: 4.74 +/- 0.42 to 6.91 +/- 0.65 pmol/l, p less than 0.01; group B: 3.60 +/- 0.48 to 5.14 +/- 0.22 pmol/l, p less than 0.05, and remained at 5.05 +/- 0.65 pmol/l on the 10th day (group B: 0.05 less than p less than 0.1) during fasting. Group B had lower levels of plasma beta-EP on the 5th day of fasting than group A (p less than 0.05). However, serum cortisol levels changed similarly in both groups. Plasma beta-EP showed no significant correlation with either the percentage of body weight lost or the body mass index (kg/m2) over this study period. These findings indicate that plasma beta-EP is elevated in the early phase of fasting, while not directly being associated with body weight changes. Plasma beta-EP is lower and less activated in subjects who are able to tolerate fasting for longer periods.
1990
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1159/000181525" target="_blank" rel="noreferrer">10.1159/000181525</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1990
Adolescent
Adult
Backlog
beta-Endorphin/blood
Blood Urea Nitrogen
Body Weight
Cholesterol/blood
Creatinine/blood
Fasting/metabolism
Female
Homeostasis/drug effects
Hormone Research
Humans
Hydrocortisone/blood
Journal Article
Kobayashi N
Komaki G
Male
Mori K
Mori S
Mori T
Nakagawa T
Sumioki H
Tamai H
Uric Acid/blood
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1016/0196-9781(95)00030-n" target="_blank" rel="noreferrer">http://doi.org/10.1016/0196-9781(95)00030-n</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Age-related changes in mitogen-induced beta-endorphin release from human peripheral blood mononuclear cells
Publisher
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Peptides
Date
A point or period of time associated with an event in the lifecycle of the resource
1995
Subject
The topic of the resource
Humans; Adult; Middle Aged; Biomarkers of Pain; Leukocytes; Aging/blood; beta-Endorphin/metabolism; Calcium-Transporting ATPases/antagonists & inhibitors; Calcium/blood; Concanavalin A/pharmacology; Homeostasis/drug effects; Ionomycin/pharmacology; Mitogens/pharmacology; Mononuclear/cytology/drug effects; Phytohemagglutinins/pharmacology; Terpenes/pharmacology; Thapsigargin
Creator
An entity primarily responsible for making the resource
Manfredi B; Clementi E; Sacerdote P; Bassetti M; Panerai AE
Description
An account of the resource
beta-Endorphin is an opioid peptide synthesized in the pituitary, hypothalamus, and immunocytes, known to affect immune responses both when added in vitro and when its synthesis is increased in vivo (e.g., during stress). We show here that, similar to its concentrations in peripheral blood mononuclear cells, the release of the opioid peptide from these cells after stimulation with polyclonal mitogens such as PHA or Con-A is also age dependent. Moreover, the effect of both mitogens on Ca2+ homeostasis changes with age. Finally, the ionophore ionomycin and the Ca2+ ATPase blocker thapsigargin induce the same age related effect on beta-endorphin release. For these reasons, we suggest that calcium homeostasis might be important for the differences observed in the release of the opioid from cells obtained from younger ( or = 45 years) volunteers.
1995
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0196-9781(95)00030-n" target="_blank" rel="noreferrer">10.1016/0196-9781(95)00030-n</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1995
Adult
Aging/blood
Backlog
Bassetti M
beta-Endorphin/metabolism
Biomarkers of Pain
Calcium-Transporting ATPases/antagonists & inhibitors
Calcium/blood
Clementi E
Concanavalin A/pharmacology
Homeostasis/drug effects
Humans
Ionomycin/pharmacology
Journal Article
Leukocytes
Manfredi B
Middle Aged
Mitogens/pharmacology
Mononuclear/cytology/drug effects
Panerai AE
Peptides
Phytohemagglutinins/pharmacology
Sacerdote P
Terpenes/pharmacology
Thapsigargin