1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1007/978-3-540-33823-9_2" target="_blank" rel="noreferrer">http://doi.org/10.1007/978-3-540-33823-9_2</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Opioids
Publisher
An entity responsible for making the resource available
Handbook Of Experimental Pharmacology
Date
A point or period of time associated with an event in the lifecycle of the resource
2007
Subject
The topic of the resource
Humans; Analgesics; Animals; Molecular Sequence Data; Chronic disease; Biomarkers of Pain; Drug Tolerance; Receptors; Amino Acid Sequence; Ligands; Opioid/adverse effects/pharmacology/therapeutic use; Opioid/drug effects
Creator
An entity primarily responsible for making the resource
Zollner C; Stein C
Description
An account of the resource
Opioids are the most effective and widely used drugs in the treatment of severe pain. They act through G protein-coupled receptors. Four families of endogenous ligands (opioid peptides) are known. The standard exogenous opioid analgesic is morphine. Opioid agonists can activate central and peripheral opioid receptors. Three classes of opioid receptors (mu, delta, kappa) have been identified. Multiple pathways ofopioid receptor signaling (e.g., G(i/o) coupling, cAMP inhibition, Ca++ channel inhibition) have been described. The differential regulation of effectors, preclinical pharmacology, clinical applications, and side effects will be reviewed in this chapter.
2007
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/978-3-540-33823-9_2" target="_blank" rel="noreferrer">10.1007/978-3-540-33823-9_2</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2007
Amino Acid Sequence
Analgesics
Animals
Backlog
Biomarkers of Pain
Chronic Disease
Drug Tolerance
Handbook Of Experimental Pharmacology
Humans
Journal Article
Ligands
Molecular Sequence Data
Opioid/adverse effects/pharmacology/therapeutic use
Opioid/drug effects
Receptors
Stein C
Zollner C