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Text
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<a href="http://doi.org/10.1111/j.1440-1746.2005.03993.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1440-1746.2005.03993.x</a>
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Title
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Morbidity and mortality after percutaneous endoscopic gastrostomy in children with neurological disability
Publisher
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Journal Of Gastroenterology And Hepatology
Date
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2006
Subject
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Child; Female; Humans; Male; Survival Rate; Adult; Treatment Outcome; Comorbidity; Survival Analysis; Risk Factors; Incidence; adolescent; Preschool; infant; Nutritional Failure; Australia/epidemiology; Endoscopy; Gastrointestinal/mortality; Gastrostomy/mortality; Malnutrition/mortality/prevention & control; Nervous System Diseases/mortality/surgery; Risk Assessment/methods
Creator
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Catto-Smith AG; Jimenez S
Description
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BACKGROUND AND AIM: Gastrostomy placement has become an integral mechanism for delivering nutritional support to children with severe neurological disability. Its impact on gastroesophageal reflux and mortality remains contentious. We examined the morbidity and long-term mortality of a group of children with severe neurological disability after percutaneous endoscopic gastrostomy (PEG). METHODS: We retrospectively identified all children with severe neurological disability who had a PEG at the Royal Children's Hospital in Melbourne between 1990 and 1997. Data were obtained from medical records. RESULTS: Ninety-eight children with neurological disability (M:F 1.8:1.0; median age 3.5 years, interquartile range 1.1-8.7 years) had an initial PEG in this period and were able to be followed for 6-14 years. As a group, they were underweight for their age with a Z score at PEG of -3.52 (SD 3.33), but had increased weight-for-age Z scores by 1.05 after a mean period of 6.1 months. Fourteen subsequently required fundoplication for reflux. Mortality rates were 11% after 1 year, 21% after 2 years, 27% after 3 years and 39% after 13 years. Mortality was increased in those children who were older at the time of PEG (P = 0.06). Gastroesophageal reflux, underweight-for-age and gender were not significantly related to mortality. CONCLUSION: Children with severe neurological dysfunction who require gastrostomy feeding have a substantial long-term mortality, but this may be unrelated to PEG placement.
2006
Identifier
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<a href="http://doi.org/10.1111/j.1440-1746.2005.03993.x" target="_blank" rel="noreferrer">10.1111/j.1440-1746.2005.03993.x</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2006
Adolescent
Adult
Australia/epidemiology
Backlog
Catto-Smith AG
Child
Comorbidity
Endoscopy
Female
Gastrointestinal/mortality
Gastrostomy/mortality
Humans
Incidence
Infant
Jimenez S
Journal Article
Journal Of Gastroenterology And Hepatology
Male
Malnutrition/mortality/prevention & control
Nervous System Diseases/mortality/surgery
Nutritional Failure
Preschool
Risk Assessment/methods
Risk Factors
Survival Analysis
Survival Rate
Treatment Outcome