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40
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1002/cncr.21497" target="_blank" rel="noreferrer">http://doi.org/10.1002/cncr.21497</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Transdermal fentanyl in the management of children with chronic severe pain: results from an international study
Publisher
An entity responsible for making the resource available
Cancer
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
Subject
The topic of the resource
Child; Female; Humans; Male; Pain; Pain Measurement; Analgesics; Follow-Up Studies; Severity of Illness Index; Risk Assessment; Single-Blind Method; International Cooperation; adolescent; Preschool; Chronic disease; Administration; Dose-Response Relationship; Drug; Opioid/administration & dosage; Cutaneous; Fentanyl/administration & dosage; Intractable/diagnosis/drug therapy; Skin Absorption/drug effects
Creator
An entity primarily responsible for making the resource
Finkel JC; Finley A; Greco C; Weisman SJ; Zeltzer L
Description
An account of the resource
BACKGROUND: The current study was conducted to assess the safety and tolerability of a transdermal fentanyl delivery system for the relief of chronic pain in a pediatric population, and also to validate titration recommendations and conversion to transdermal fentanyl from oral opioid therapy. METHODS: This 15-day (with 3-month extension), single-arm, open-label trial was conducted at 66 sites in 10 countries. A total of 199 pediatric patients (ages 2-16 years) with both malignant and nonmalignant conditions who were receiving oral or parenteral opioids for moderate to severe chronic pain were enrolled. Transdermal fentanyl doses were titrated upward according to the rescue medication consumed during the previous application period. Degree of pain was assessed by patients and parents/guardians using visual and numeric scales. Level of play and quality of life were assessed using the Play Performance Scale (PPS) and the Child Health Questionnaire (CHQ). Adverse events were monitored on Days 1-15. Hypoventilation and sedation were monitored every 4 hours during the first 72 hours of the study. RESULTS: A total of 173 patients completed the primary treatment period and 130 entered the extension phase. The average daily pain intensity scores were reported to have decreased by Day 16 and improvements in the mean PPS scores were observed to the end of the extension period. The CHQ scores demonstrated improvements in 11 of 12 domains after Month 1 of the extension period. CONCLUSIONS: Transdermal fentanyl was found to be a safe and well tolerated alternative to oral opioid treatment for children ages 2-16 years who were previously exposed to opioid therapy.
2005
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/cncr.21497" target="_blank" rel="noreferrer">10.1002/cncr.21497</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2005
Administration
Adolescent
Analgesics
Backlog
Cancer
Child
Chronic Disease
Cutaneous
Dose-Response Relationship
Drug
Female
Fentanyl/administration & dosage
Finkel JC
Finley A
Follow-up Studies
Greco C
Humans
International Cooperation
Intractable/diagnosis/drug therapy
Journal Article
Male
Opioid/administration & dosage
Pain
Pain Measurement
Preschool
Risk Assessment
Severity Of Illness Index
Single-Blind Method
Skin Absorption/drug effects
Weisman SJ
Zeltzer L
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1097/01241398-199807000-00018" target="_blank" rel="noreferrer">http://doi.org/10.1097/01241398-199807000-00018</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Epidural analgesia for postoperative pain control in children
Publisher
An entity responsible for making the resource available
Journal Of Pediatric Orthopedics
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
Subject
The topic of the resource
Child; Female; Humans; Male; Pain; Pain Measurement; Prognosis; Treatment Outcome; Drug Therapy; Length of Stay; Analgesia; Anesthetics; adolescent; Preschool; infant; Comparative Study; Dose-Response Relationship; Drug; Fentanyl/administration & dosage; Adjuvants; Postoperative/drug therapy; Combination; Anesthesia/administration & dosage; Bupivacaine/administration & dosage; Epidural/methods; Local/administration & dosage
Creator
An entity primarily responsible for making the resource
Jones MD; Aronsson DD; Harkins JM; Smail DF; Haugh LD
Description
An account of the resource
Ninety-eight continuous postoperative epidurals were administered to 87 children. The patients were divided into two groups: group I included 63 cases in which a 0.0625-0.25% solution of bupivacaine was continuously administered; group II included 35 cases in which a similar solution of bupivacaine mixed with 2-10 micrograms of fentanyl was administered. The dose of the epidural medication was titrated by the anesthesiologist according to the patient's age and anticipated level of postoperative pain. The average pain score for all patients for the first 48 h was 1.43. Supplemental analgesia averaging 0.132 mg intravenous morphine/kg/8 h was required in 49 cases (41 in group I and eight in group II). In group I, the average dose of supplemental analgesia was 0.144 mg intravenous morphine/kg/8 h, whereas in group II, it was only 0.056 mg intravenous morphine/kg/8 h. Continuous epidural analgesia is effective in controlling postoperative pain, and the addition of fentanyl reduces the need for systemic narcotics.
1998
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/01241398-199807000-00018" target="_blank" rel="noreferrer">10.1097/01241398-199807000-00018</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1998
Adjuvants
Adolescent
Analgesia
Anesthesia/administration & dosage
Anesthetics
Aronsson DD
Backlog
Bupivacaine/administration & dosage
Child
Combination
Comparative Study
Dose-Response Relationship
Drug
Drug Therapy
Epidural/methods
Female
Fentanyl/administration & dosage
Harkins JM
Haugh LD
Humans
Infant
Jones MD
Journal Article
Journal Of Pediatric Orthopedics
Length Of Stay
Local/administration & dosage
Male
Pain
Pain Measurement
Postoperative/drug therapy
Preschool
Prognosis
Smail DF
Treatment Outcome
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11591092" target="_blank" rel="noreferrer">http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11591092</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Transdermal fentanyl for pain relief in a paediatric palliative care population
Publisher
An entity responsible for making the resource available
Palliative Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
Subject
The topic of the resource
Child; Female; Male; Palliative Care; Pain Measurement; Terminally Ill; Analgesics; Parents; Treatment Outcome; Patient Satisfaction; adolescent; Preschool; Non-U.S. Gov't; Administration; Human; Cutaneous; Support; Pain/drug therapy; Opioid/administration & dosage; Fentanyl/administration & dosage
Creator
An entity primarily responsible for making the resource
Hunt A; Goldman A; Devine T; Phillips M
Description
An account of the resource
This multicentre, observational study examined the efficacy of the therapeutic transdermal fentanyl system (TTS-fentanyl) in children requiring opioids for pain in life-threatening disease. Forty-one children receiving oral morphine (median dose 60 mg/day) transferred to transdermal fentanyl (median dose 25 micrograms/h according with the manufacturer's dose conversion guidelines). Twenty-six children completed the 15-day treatment phase, seven died due to disease progression and eight were withdrawn because of adverse events, inadequate analgesia or a change to parenteral opioids. After 15 days, the median fentanyl dose was 75 micrograms/h (range 25-250). No serious adverse events were attributed to fentanyl. There was a trend toward improved side-effects and convenience with fentanyl. Twenty-three of 26 parents (three missing) and 25 of 26 investigators considered transdermal fentanyl to be better than previous treatment. For all records available (at 15 days or on withdrawal if earlier), 75% (27/36) reported that fentanyl treatment was 'good' or 'very good'. The findings suggest that transdermal fentanyl is both effective and acceptable for children and their families.
2001
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2001
Administration
Adolescent
Analgesics
Backlog
Child
Cutaneous
Devine T
Female
Fentanyl/administration & dosage
Goldman A
Human
Hunt A
Journal Article
Male
Non-U.S. Gov't
Opioid/administration & dosage
Pain Measurement
Pain/drug Therapy
Palliative Care
Palliative Medicine
Parents
Patient Satisfaction
Phillips M
Preschool
Support
Terminally Ill
Treatment Outcome