Sleep dysfunction in Rett syndrome: lack of age related decrease in sleep duration
Age Factors; Child; Humans; Adolescent; Cohort Studies; Female; Child Preschool; Brain; Sleep; Epilepsy; Movement Disorders; Sleep Wake Disorders; Rett Syndrome; sleep disturbance/disorders; trajectory; characteristics
The sleep patterns of a cohort of 83 Rett syndrome females were characterized using a sleep diary for 7 consecutive days and nights and compared with normative sleep data. The mean total sleep time of the cohort was 10.75 h, daytime sleep 0.77 h, sleep efficiency 89.7%, and sleep latency 0.52 h. When subjects were categorized according to age and Rett syndrome classification, there was no significant difference in their sleep characteristics. There was a significant difference in the percentage predicted total sleep time (P<0.001) and Z scores for total sleep time (P<0.001), when subjects were categorized according to age and compared with normal children. The Rett syndrome subjects in this study did not show the age related decrease in total and daytime sleep time seen in normal children. The immature sleep pattern demonstrated in this cohort, may be a consequence of arrested brain development.
Peat J; Leonard H; Christodoulou J; Ellaway C
Brain and Development
2001
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1016/s0387-7604(01)00356-4" target="_blank" rel="noreferrer noopener">10.1016/s0387-7604(01)00356-4</a>
Development of a video-based evaluation tool in Rett syndrome
Male; Diagnosis Differential; Child; Humans; Adult; Adolescent; Female; Phenotype; Feasibility Studies; Videotape Recording; Movement Disorders/diagnosis/etiology; Rett Syndrome/complications/diagnosis; feeding difficulties; tone and motor problems; Rett syndrome; tool development; scale development; filming and coding protocol
This paper describes the development of a video-based evaluation tool for use in Rett syndrome (RTT). Components include a parent-report checklist, and video filming and coding protocols that contain items on eating, drinking, communication, hand function and movements, personal care and mobility. Ninety-seven of the 169 families who initially agreed to participate returned a videotape within 8 months of the first request. Subjects whose videos were returned had a similar age profile to those who did not provide a video but were more likely to have classical than atypical RTT. Evidence of the content and social validity and inter-rater reliability on 11 videos is provided. Video may provide detailed, objective assessment of function and behaviour in RTT.
Fyfe S; Downs J; McIlroy O; Burford B; Lister J; Reilly S; Laurvick C L; Philippe C; Msall M; Kaufmann W E; Ellaway C; Leonard H
Journal of Autism and Developmental Disorders
2007
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1007/s10803-006-0293-9" target="_blank" rel="noreferrer noopener">10.1007/s10803-006-0293-9</a>