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Text
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URL Address
<a href="http://doi.org/10.1089/152308604773934378" target="_blank" rel="noreferrer">http://doi.org/10.1089/152308604773934378</a>
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Title
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Nitric oxide as a prognostic marker for neurological diseases
Publisher
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Antioxidants & Redox Signaling
Date
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2004
Subject
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Child; Humans; Adult; Prognosis; Animals; Biomarkers of Pain; Brain/pathology; Children W/SNI; Brain Neoplasms/cerebrospinal fluid/diagnosis; Cerebrospinal Fluid; Craniocerebral Trauma/cerebrospinal fluid/diagnosis; Electron Spin Resonance Spectroscopy/methods; Meningitis/cerebrospinal fluid/diagnosis; Nervous System Diseases/cerebrospinal fluid/diagnosis/mortality; Nitric Oxide/cerebrospinal fluid/metabolism
Creator
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Bratasz A; Kuter I; Konior R; Goscinski I; Lukiewicz S
Description
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The potential value of the nitric oxide (NO) level as a prognostic marker in human brain diseases is investigated. Cerebrospinal fluid (CSF) collected from neurological patients was examined for NO content using electron paramagnetic resonance (EPR) spectroscopy. In adult patients with meningitis, the level of NO was higher than that in other groups of brain disorders, such as brain traumas and brain tumors. Very high levels of NO in the CSF appeared to be correlated with a high incidence of fatal outcomes. In children with meningitis, it was possible to differentiate between viral and bacterial origin of the disease as evidenced by the EPR analysis of the CSF. The results indicated that NO levels in the CSF can be a useful prognostic marker in neurological diseases.
2004
Identifier
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<a href="http://doi.org/10.1089/152308604773934378" target="_blank" rel="noreferrer">10.1089/152308604773934378</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2004
Adult
Animals
Antioxidants & Redox Signaling
Backlog
Biomarkers of Pain
Brain Neoplasms/cerebrospinal fluid/diagnosis
Brain/pathology
Bratasz A
Cerebrospinal Fluid
Child
Children W/SNI
Craniocerebral Trauma/cerebrospinal fluid/diagnosis
Electron Spin Resonance Spectroscopy/methods
Goscinski I
Humans
Journal Article
Konior R
Kuter I
Lukiewicz S
Meningitis/cerebrospinal fluid/diagnosis
Nervous System Diseases/cerebrospinal fluid/diagnosis/mortality
Nitric Oxide/cerebrospinal fluid/metabolism
Prognosis