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Text
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URL Address
<a href="http://doi.org/10.1016/j.jclinepi.2013.02.003" target="_blank" rel="noreferrer">http://doi.org/10.1016/j.jclinepi.2013.02.003</a>
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Title
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GRADE guidelines: 15. Going from evidence to recommendation-determinants of a recommendation's direction and strength
Publisher
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Journal Of Clinical Epidemiology
Date
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2013
Subject
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Humans; United States; Canada; Practice Guidelines as Topic; Treatment Outcome; Research Design; Risk Assessment; Evidence-Based Medicine; Treatment Failure; Germany; Pulmonary Disease; Health Care; Quality Assurance; Chronic Obstructive
Creator
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Andrews JC; Schunemann HJ; Oxman A; Pottie K; Meerpohl Joerg J; Coello PA; Rind D; Montori VM; Brito JP; Norris S; Elbarbary M; Post P; Nasser M; Shukla V; Jaeschke R; Brozek J; Djulbegovic B; Guyatt G
Description
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In the GRADE approach, the strength of a recommendation reflects the extent to which we can be confident that the composite desirable effects of a management strategy outweigh the composite undesirable effects. This article addresses GRADE's approach to determining the direction and strength of a recommendation. The GRADE describes the balance of desirable and undesirable outcomes of interest among alternative management strategies depending on four domains, namely estimates of effect for desirable and undesirable outcomes of interest, confidence in the estimates of effect, estimates of values and preferences, and resource use. Ultimately, guideline panels must use judgment in integrating these factors to make a strong or weak recommendation for or against an intervention.
2013-07
Identifier
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<a href="http://doi.org/10.1016/j.jclinepi.2013.02.003" target="_blank" rel="noreferrer">10.1016/j.jclinepi.2013.02.003</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2013
Andrews JC
Backlog
Brito JP
Brozek J
Canada
Chronic Obstructive
Coello PA
Djulbegovic B
Elbarbary M
Evidence-based Medicine
Germany
Guyatt G
Health Care
Humans
Jaeschke R
Journal Article
Journal Of Clinical Epidemiology
Meerpohl Joerg J
Montori VM
Nasser M
Norris S
Oxman A
Post P
Pottie K
Practice Guidelines As Topic
Pulmonary Disease
Quality Assurance
Research Design
Rind D
Risk Assessment
Schunemann HJ
Shukla V
Treatment Failure
Treatment Outcome
United States