1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month Backlog URL Address <a href="http://doi.org/10.1016/j.tips.2005.01.009" target="_blank" rel="noreferrer">http://doi.org/10.1016/j.tips.2005.01.009</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Individual responder analyses for pain: does one pain scale fit all? Publisher An entity responsible for making the resource available Trends In Pharmacological Sciences Date A point or period of time associated with an event in the lifecycle of the resource 2005 Subject The topic of the resource Humans; Reproducibility of Results; P.H.S.; Research Support; U.S. Gov't; Comparative Study; Pain/drug therapy/physiopathology; Clinical Trials/methods/trends; Pain Measurement/drug effects/methods/standards Creator An entity primarily responsible for making the resource Dionne RA; Bartoshuk L; Mogil J; Witter J Description An account of the resource The outcomes of clinical trials are based on the mean responses of large numbers of subjects but fail to address inter-individual differences. The molecular mechanisms that underlie pain vary among individuals over time and among different types of pain to produce wide inter-individual variations in pain perception and response. Gender, ethnicity, temperament and genetic factors also contribute to individual variation in pain sensitivity and responses to analgesics. Pain measurement scales can be used differently across individuals based on the past pain experiences of individuals. We propose that individual responder analyses could be used in clinical trials to better detect analgesic activity across patient groups and within sub-groups, and to identify molecular-genetic mechanisms that contribute to individual variation. 2005 Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.tips.2005.01.009" target="_blank" rel="noreferrer">10.1016/j.tips.2005.01.009</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). Type The nature or genre of the resource Journal Article 2005 Backlog Bartoshuk L Clinical Trials/methods/trends Comparative Study Dionne RA Humans Journal Article Mogil J P.H.S. Pain Measurement/drug effects/methods/standards Pain/drug therapy/physiopathology Reproducibility of Results Research Support Trends In Pharmacological Sciences U.S. Gov't Witter J