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Gabapentin Successfully Manages Chronic Unexplained Irritability in Children With Severe Neurologic Impairment

Neurologically impaired children have an increased frequency of recurrent pain and irritability that persist in some despite comprehensive evaluation and management of possible pain sources. We hypothesized that visceral hyperalgesia was a source of…

Tags: 2007, Adolescent, Adult, Amines/therapeutic use, amitriptyline/dt [Drug Therapy], Analgesics/therapeutic use, Article, brain disease, brain ischemia, Charnas L, Child, Child Preschool, Chronic Disease, Clinical Article, Clinical Feature, Controlled Study, Cyclohexanecarboxylic Acids/therapeutic use, drug dose titration, Drug Withdrawal, Female, Gabapentin, gabapentin/ae [Adverse Drug Reaction], gabapentin/dt [Drug Therapy], gamma-Aminobutyric Acid/therapeutic use, gastritis, Hauer Julie M, Human, Humans, hyperalgesia/dt [Drug Therapy], Infant, infantile spasm, intestinal dysmotility, Irritability, Irritable Mood/drug effects, Male, Nervous System Diseases/complications, NET Files, neurologic disease/dt [Drug Therapy], neurological impairment, nystagmus/si [Side Effect], Pain, Pediatrics, Priority Journal, proton pump inhibitor, Remission Induction, Retrospective Studies, salazosulfapyridine, Severity Of Illness Index, steroid, symptomatology, tricyclic antidepressant agent/dt [Drug Therapy], visceral hyperalgesia, Wical B S

Outcome reporting in industry-sponsored trials of gabapentin for off-label use

BACKGROUND: There is good evidence of selective outcome reporting in published reports of randomized trials. METHODS: We examined reporting practices for trials of gabapentin funded by Pfizer and Warner-Lambert's subsidiary, Parke-Davis (hereafter…

Gabapentin Successfully Manages Chronic Unexplained Irritability in Children With Severe Neurologic Impairment

Neurologically impaired children have an increased frequency of recurrent pain and irritability that persist in some despite comprehensive evaluation and management of possible pain sources. We hypothesized that visceral hyperalgesia was a source of…

Empirical evidence for the use of lithium and anticonvulsants in children with psychiatric disorders

BACKGROUND: The use of psychotropic medications-in particular, mood stabilizers--in youths with psychiatric illness has grown. There are trends toward polypharmacy and the increased use of newer mood stabilizers in youths with psychiatric illness…

Abdominal pain related to mitochondrial neurogastrointestinal encephalomyopathy syndrome may benefit from splanchnic nerve blockade

Patients diagnosed with abdominal pain related to mitochondrial neurogastrointestinal encephalopathy (MNGIE) may benefit from splanchnic nerve blockade. MNGIE, varying in age of onset and rate of progression, is caused by loss of function mutation in…

Browse Items (5 total)

Gabapentin Successfully Manages Chronic Unexplained Irritability in Children With Severe Neurologic Impairment

Outcome reporting in industry-sponsored trials of gabapentin for off-label use

Gabapentin Successfully Manages Chronic Unexplained Irritability in Children With Severe Neurologic Impairment

Empirical evidence for the use of lithium and anticonvulsants in children with psychiatric disorders

Abdominal pain related to mitochondrial neurogastrointestinal encephalomyopathy syndrome may benefit from splanchnic nerve blockade