1
40
4
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Text
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URL Address
<a href="http://doi.org/10.1016/S0140-6736(10)61115-4" target="_blank" rel="noreferrer">http://doi.org/10.1016/S0140-6736(10)61115-4</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: a double-blind, randomised controlled trial
Publisher
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Lancet
Date
A point or period of time associated with an event in the lifecycle of the resource
2010
Subject
The topic of the resource
Female; Humans; Male; United States; Great Britain; Adult; Aged; Middle Aged; Treatment Outcome; Australia; Sleep Stages; Double-Blind Method; quality of life; Palliative Care/methods; Sleep; Air; Anxiety/chemically induced; Dyspnea/drug therapy/therapy; Epistaxis/chemically induced; Oxygen/administration & dosage/adverse effects/blood
Creator
An entity primarily responsible for making the resource
Abernethy AP; McDonald CF; Frith PA; Clark K; Herndon JE; Marcello J; Young IH; Bull J; Wilcock A; Booth S; Wheeler JL; Tulsky JA; Crockett AJ; Currow DC
Description
An account of the resource
BACKGROUND: Palliative oxygen therapy is widely used for treatment of dyspnoea in individuals with life-limiting illness who are ineligible for long-term oxygen therapy. We assessed the effectiveness of oxygen compared with room air delivered by nasal cannula for relief of breathlessness in this population of patients. METHODS: Adults from outpatient clinics at nine sites in Australia, the USA, and the UK were eligible for enrolment in this double-blind, randomised controlled trial if they had life-limiting illness, refractory dyspnoea, and partial pressure of oxygen in arterial blood (PaO(2)) more than 7.3 kPa. Participants were randomly assigned in a 1:1 ratio by a central computer-generated system to receive oxygen or room air via a concentrator through a nasal cannula at 2 L per min for 7 days. Participants were instructed to use the concentrator for at least 15 h per day. The randomisation sequence was stratified by baseline PaO(2) with balanced blocks of four patients. The primary outcome measure was breathlessness (0-10 numerical rating scale [NRS]), measured twice a day (morning and evening). All randomised patients who completed an assessment were included in the primary analysis for that data point (no data were imputed). This study is registered, numbers NCT00327873 and ISRCTN67448752. FINDINGS: 239 participants were randomly assigned to treatment (oxygen, n=120; room air, n=119). 112 (93%) patients assigned to receive oxygen and 99 (83%) assigned to receive room air completed all 7 days of assessments. From baseline to day 6, mean morning breathlessness changed by -0.9 points (95% CI -1.3 to -0.5) in patients assigned to receive oxygen and by -0.7 points (-1.2 to -0.2) in patients assigned to receive room air (p=0.504). Mean evening breathlessness changed by -0.3 points (-0.7 to 0.1) in the oxygen group and by -0.5 (-0.9 to -0.1) in the room air group (p=0.554). The frequency of side-effects did not differ between groups. Extreme drowsiness was reported by 12 (10%) of 116 patients assigned to receive oxygen compared with 14 (13%) of 108 patients assigned to receive room air. Two (2%) patients in the oxygen group reported extreme symptoms of nasal irritation compared with seven (6%) in the room air group. One patient reported an extremely troublesome nose bleed (oxygen group). INTERPRETATION: Since oxygen delivered by a nasal cannula provides no additional symptomatic benefit for relief of refractory dyspnoea in patients with life-limiting illness compared with room air, less burdensome strategies should be considered after brief assessment of the effect of oxygen therapy on the individual patient. FUNDING: US National Institutes of Health, Australian National Health and Medical Research Council, Duke Institute for Care at the End of Life, and Doris Duke Charitable Foundation.
2010
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/S0140-6736(10)61115-4" target="_blank" rel="noreferrer">10.1016/S0140-6736(10)61115-4</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2010
Abernethy AP
Adult
Aged
Air
Anxiety/chemically induced
Australia
Backlog
Booth S
Bull J
Clark K
Crockett AJ
Currow DC
Double-Blind Method
Dyspnea/drug therapy/therapy
Epistaxis/chemically induced
Female
Frith PA
Great Britain
Herndon JE
Humans
Journal Article
Lancet
Male
Marcello J
McDonald CF
Middle Aged
Oxygen/administration & dosage/adverse effects/blood
Palliative Care/methods
Quality Of Life
Sleep
Sleep Stages
Treatment Outcome
Tulsky JA
United States
Wheeler JL
Wilcock A
Young IH
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1089/jpm.2010.0392" target="_blank" rel="noreferrer">http://doi.org/10.1089/jpm.2010.0392</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Adverse events in hospice and palliative care: a pilot study to determine feasibility of collection and baseline rates
Publisher
An entity responsible for making the resource available
Journal Of Palliative Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
Subject
The topic of the resource
Female; Humans; Male; Young Adult; Adult; Aged; Middle Aged; Pilot Projects; Feasibility Studies; Australia; Urinary Retention; 80 and over; retrospective studies; Palliative Care/standards; Hospice Care/standards; Accidental Falls; Confusion; Hyperglycemia; Hypoglycemia; Hypotension
Creator
An entity primarily responsible for making the resource
Currow DC; Agar MR; To TH; Rowett D; Greene A; Abernethy AP
Description
An account of the resource
BACKGROUND: Continuous quality improvement is fundamental in all health care, including hospice and palliative care. Identifying and systematically reducing symptomatic adverse events is limited in hospice and palliative care because these events are mostly attributed to disease progression. OBJECTIVES: The aim of this study was to assess the feasibility of symptomatic adverse events in hospice and palliative care and assessing their incidence. METHODS: A retrospective, consecutive cohort of notes from a specialist palliative care inpatient service was surveyed by a clinical nurse consultant for symptomatic adverse events: falls, confusion, decreased consciousness, hypo- and hyperglycaemia, urinary retention, and hypotension. Demographic and clinical factors were explored for people at higher risk. RESULTS: Data were available on the most recent admissions of 65 people, generating >900 inpatient days. Fifty people (78%) had events precipitating admission, of whom 31 (62%) had at least one further event during admission. Eleven of 15 people who were admitted without an event experienced at least one during their admissions. Only 4 did not have an adverse event. During their stay, there were 0.13 (standard deviation [SD] = 0.19) events per patient per day. No drug-drug or drug-host events were noted. No clinical or demographic factors predicted groups at higher risk. CONCLUSIONS: This pilot highlights the feasibility of collecting, and ubiquity of, symptomatic adverse events, and forms a baseline against which future interventions to decrease the frequency or intensity can be measured. Given the frailty of hospice and palliative patients, any adverse event is likely to accelerate irreversibly their systemic decline.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1089/jpm.2010.0392" target="_blank" rel="noreferrer">10.1089/jpm.2010.0392</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2011
80 And Over
Abernethy AP
Accidental Falls
Adult
Agar MR
Aged
Australia
Backlog
Confusion
Currow DC
Feasibility Studies
Female
Greene A
Hospice Care/standards
Humans
Hyperglycemia
Hypoglycemia
Hypotension
Journal Article
Journal of Palliative Medicine
Male
Middle Aged
Palliative Care/standards
Pilot Projects
Retrospective Studies
Rowett D
To TH
Urinary Retention
Young Adult
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1200/JCO.2012.42.1081" target="_blank" rel="noreferrer">http://doi.org/10.1200/JCO.2012.42.1081</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Randomized, double-blind, placebo-controlled study to assess the efficacy and toxicity of subcutaneous ketamine in the management of cancer pain
Publisher
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Journal Of Clinical Oncology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
Creator
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Hardy J; Quinn S; Fazekas B; Plummer J; Eckermann S; Agar M; Spruyt O; Rowett D; Currow DC
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1200/JCO.2012.42.1081" target="_blank" rel="noreferrer">10.1200/JCO.2012.42.1081</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2012
Agar M
Backlog
Currow DC
Eckermann S
Fazekas B
Hardy J
Journal Article
Journal Of Clinical Oncology
Plummer J
Quinn S
Rowett D
Spruyt O
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
May 2016 List
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Assessing The Presence And Severity Of Constipation With Plain Radiographs In Constipated Palliative Care Patients.
Publisher
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Journal Of Palliative Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
Palliative And Supportive Care; Constipation; Australia; Gastroenterology
Creator
An entity primarily responsible for making the resource
Clark K; Lam LT; Talley NJ; Quinn J; Blight A; Byfieldt N; Currow DC
Description
An account of the resource
BACKGROUND:
Palliative care guidelines recommend plain radiographs to assess constipation based on the presumption that visible fecal shadowing represents stool retention. Despite this, using plain radiographs in this way is not well validated.
OBJECTIVES:
This work's main aim was to compare clinicians' reports of fecal loading on radiographs. This study also compares clinicians' assessments with radio-opaque marker transit studies and patients' self-reported constipation symptoms.
METHODS:
This study was conducted in a sample of 30 constipated palliative care patients taking laxatives who had all undergone colon transit studies and contemporaneous assessment of constipation symptoms with the Patient Assessment of Constipation Symptom (PAC-SYM) questionnaire. Four separate clinicians independently reported their opinions of fecal loading using a previously developed fecal loading scale. Participant details were summarized and pair-wise inter-rater agreement among all four raters were examined using the Bland-Altman approach. For the comparisons of the clinician-assigned fecal loading score between the radiographic assessment of the normal and slow colon transit time, the nonparametric approach of Mann-Whitney U tests were applied. Spearman's correlation analyses were employed to investigate the association between the clinician-assigned fecal loading score and the patient self-reported PAC-SYM score.
RESULTS:
The results of this study are very similar to other studies conducted in functional constipation, highlighting systematic disagreement between observers. Further poor correlations were noted between fecal loading scores and colon transit times and with patient self-reported symptoms.
CONCLUSION:
These results, when considered with other work in chronic constipation, question the ongoing use of radiographs in the diagnosis of constipation.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
Australia
Blight A
Byfieldt N
Clark K
Constipation
Currow DC
Gastroenterology
Journal of Palliative Medicine
Lam LT
May 2016 List
Palliative And Supportive Care
Quinn J
Talley NJ