1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Backlog
URL Address
<a href="http://doi.org/10.1136/thx.2003.010793" target="_blank" rel="noreferrer">http://doi.org/10.1136/thx.2003.010793</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Open lung biopsy in neonatal and paediatric patients referred for extracorporeal membrane oxygenation (ECMO)
Publisher
An entity responsible for making the resource available
Thorax
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
Subject
The topic of the resource
Child; Humans; infant; Extracorporeal Membrane Oxygenation; infant; referral and consultation; Newborn; retrospective studies; Heart Defects; Safety; Biopsy/methods; Congenital/pathology; Hyperplasia/pathology; Lung/pathology; Respiratory Insufficiency/pathology/surgery/therapy; Thoracotomy/methods
Creator
An entity primarily responsible for making the resource
Inwald D; Brown K; Gensini F; Malone M; Goldman A
Description
An account of the resource
BACKGROUND: This study was undertaken to determine the usefulness, safety, and most appropriate timing of open lung biopsy in infants and children considered for and on extracorporeal membrane oxygenation (ECMO) for respiratory failure. METHODS: A retrospective review of children referred for consideration of and placed on ECMO in our institution in the period 1996-2002. RESULTS: 506 patients were referred, 15 (3%) of whom underwent antemortem open lung biopsy (eight neonatal, four paediatric, and three cardiac patients). In the neonatal group open lung biopsy contributed to clinical decision making in all patients. Four neonates had a fatal lung dysplasia (three alveolar capillary dysplasia and one surfactant protein B deficiency) and treatment was withdrawn. Of the other four neonates, two had pulmonary hypoplasia, one had pulmonary lymphangiectasia, and one had meconium aspiration with mild barotrauma. Treatment was continued in these four patients and two survived. In the paediatric group the biopsies were of clinical relevance in two infants with pertussis who had lung infarction on biopsy in whom treatment was withdrawn. In the other two paediatric patients the biopsies were equivocal, treatment was continued, but both patients died. In the cardiac group, who presented perioperatively with pulmonary hypertension, the biopsies excluded a fatal lung dysplasia and severe pulmonary vascular disease but all three infants died. One patient had non-fatal bleeding complications. CONCLUSION: Open lung biopsy is clinically most useful when performed to diagnose fatal lung dysplasias in neonates and to confirm the presence of viable lung tissue in patients with acute lung injury due to pertussis infection.
2004
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1136/thx.2003.010793" target="_blank" rel="noreferrer">10.1136/thx.2003.010793</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
2004
Backlog
Biopsy/methods
Brown K
Child
Congenital/pathology
Extracorporeal Membrane Oxygenation
Gensini F
Goldman A
Heart Defects
Humans
Hyperplasia/pathology
Infant
Inwald D
Journal Article
Lung/pathology
Malone M
Newborn
Referral And Consultation
Respiratory Insufficiency/pathology/surgery/therapy
Retrospective Studies
Safety
Thoracotomy/methods
Thorax