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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
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URL Address
<a href="http://doi.org/10.1007/s00381-017-3361-x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00381-017-3361-x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Considerations in deep brain stimulation (DBS) for pediatric secondary dystonia
Publisher
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Childs Nervous System
Date
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2017
Subject
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Pediatrics; Surgery; Neurosciences & Neurology; cerebral-palsy; Deep brain stimulation; globus-pallidus internus; hemidystonia; Secondary dystonia; Pediatric neurosurgery; surgical-treatment; tone and motor problems; IND; surgical intervention; deep brain stimulation; dystonia
Creator
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Tsering D; Tochen L; Lavenstein B; Reddy S K; Granader Y; Keating R F; Oluigbo C O
Description
An account of the resource
Purpose There is a paucity of effective long-term medication treatment for secondary dystonias. In situations where significantly impairing secondary dystonias fail to respond to typical enteral medications and intrathecal (or even intraventricular) baclofen, consideration should be given to the use of deep brain stimulation (DBS). While Level I evidence and long-term follow-up clearly demonstrate the efficacy of DBS for primary dystonia, the evidence for secondary dystonia remains mixed and unclear. In this study, we report our experience with pediatric subjects who have undergone DBS for secondary dystonia. Methods We discuss the indications and outcomes of DBS procedures completed at our center. We also present a detailed discussion of the considerations in the management of these patients as well as a literature review. Results Of the four cases retrospectively examined here, all subjects experienced reductions in the severity of their dystonia (ranging from 0 to 100% on both the Barry-Albright Dystonia (BAD) and Burke-Fahn-Marsden Dystonia Rating Scale-Motor (BFMDRS-M) scales). Conclusions Pallidal DBS should be considered among children with functionally debilitating, medication-resistant secondary dystonia. Patients without fixed skeletal deformities who have experienced a short duration of symptoms are most likely to benefit from this intervention.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s00381-017-3361-x" target="_blank" rel="noreferrer noopener">10.1007/s00381-017-3361-x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
cerebral-palsy
Childs Nervous System
deep brain stimulation
Dystonia
globus-pallidus internus
Granader Y
hemidystonia
IND
Keating R F
Lavenstein B
Neurosciences & Neurology
Oluigbo C O
Pediatric neurosurgery
Pediatrics
Reddy S K
secondary dystonia
Surgery
surgical intervention
surgical-treatment
Tochen L
tone and motor problems
Tsering D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
n/a
URL Address
<a href="http://doi.org/10.1007/s00381-015-2771-x" target="_blank" rel="noreferrer">http://doi.org/10.1007/s00381-015-2771-x</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Challenges and opportunities to advance pediatric neuro-oncology care in the developing world
Publisher
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Childs Nervous System
Date
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2015
Subject
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Brain Neoplasms/ep [epidemiology];brain Neoplasms/th [therapy];developing Countries;medical Oncology;neurology; Humans
Creator
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Chan MH; Boop F; Qaddoumi I
Description
An account of the resource
PURPOSE: As the morbidity and mortality associated with communicable diseases continue to decrease in the developing world, the medical burden of childhood cancer continues to expand. Although international aid and relief groups such as the World Health Organization recognize the importance of childhood cancer, their main emphasis is on the more easily treated malignancies, such as leukemias and lymphomas, and not pediatric brain tumors, which are the second most common malignancy in children and the leading cause of cancer-related deaths in the pediatric population. Addressing the needs of these children is a growing concern of several professional neuro-oncology-related societies. Thus, the goal of this review is to describe the current state of pediatric neuro-oncology care in the developing world, address the current and future needs of the field, and help guide professional societies' efforts to contribute in a more holistic and multidisciplinary manner. METHODS: We reviewed the literature to compare the availability of neuro-oncology care in various regions of the developing world with that in higher income nations, to describe examples of successful initiatives, and to present opportunities to improve care. RESULTS: The current challenges, previous successes, and future opportunities to improve neuro-oncology care are presented. The multidisciplinary nature of neuro-oncology depends on large teams of highly specialized individuals, including neuro-oncologists, neurosurgeons, neurologists, radiologists, radiation oncologists, pathologists, palliative care specialists, oncology nurses, physical therapists, occupational therapists, speech therapists, pediatric intensivists, and social workers, among others. CONCLUSION: Pediatric neuro-oncology is one of the most complex types of medical care to deliver, as it relies on numerous specialists, subspecialists, support staff, and physical resources and infrastructure. However, with increasing collaboration and advancing technologies, developed nations can help substantially improve neuro-oncology care for children in developing nations.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s00381-015-2771-x" target="_blank" rel="noreferrer">10.1007/s00381-015-2771-x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2015
Boop F
Brain Neoplasms/ep [epidemiology]
brain Neoplasms/th [therapy]
Chan MH
Childs Nervous System
Developing Countries
Humans
Medical Oncology
Neurology
Qaddoumi I
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
November 2017 List
URL Address
<a href="https://link.springer.com/article/10.1007%2Fs00381-016-3201-4" target="_blank" rel="noreferrer">https://link.springer.com/article/10.1007%2Fs00381-016-3201-4</a>
Notes
<p>Dlouhy, Brian J<br />Miller, Brandon<br />Jeong, Anna<br />Bertrand, Mary E<br />Limbrick, David D Jr<br />Smyth, Matthew D<br />10.1007/s00381-016-3201-4</p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Palliative epilepsy surgery in Dravet syndrome-case series and review of the literature
Publisher
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Childs Nervous System
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
Corpus Callosum/su [surgery]; Epilepsies Myoclonic/di [diagnosis]; Epilepsies Myoclonic/su [surgery]; Palliative Care/td [trends]; Vagus Nerve Stimulation; Electroencephalography/td [trends]; Epilepsies Myoclonic/pp [physiopathology]; Epilepsy/di [diagnosis]; Epilepsy/pp [physiopathology]; Epilepsy/su [surgery]; Female; Humans; Infant; Male; Vagus Nerve Stimulation/td [trends]
Creator
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Dlouhy BJ; Miller B; Jeong A; Bertrand ME; Limbrick DD Jr; Smyth MD
Description
An account of the resource
PURPOSE: Dravet syndrome (DS), also known as severe myoclonic epilepsy of infancy (SMEI), is a rare genetic disorder that results in severe childhood-onset epilepsy. Children with DS initially present with seizures in the first year of life that are often associated with fevers. With age, multiple seizure types develop. There are few reports and no guidelines regarding palliative surgical treatment for DS. Therefore, we reviewed our surgical experience with DS. METHODS: We conducted a retrospective review of all patients with genetically confirmed DS who underwent either vagal nerve stimulator (VNS) implantation or corpus callosotomy (CC) from May 2001 to April 2014 at our institution. All inpatient and outpatient relevant documentation were reviewed. Demographic information, genetic mutation, operation performed, and preoperative and postoperative seizure frequency were recorded. Inclusion criteria required greater than one-year postoperative follow-up. RESULTS: Seven children with DS were assessed. Six patients were treated with VNS and one patient was treated with CC. In one child, VNS was followed by CC as a secondary procedure. Therefore, in total, eight surgeries were performed on seven patients during the study period. At least 1 year elapsed from presentation to our hospital and surgery for all patients. Average time after the first seizure to VNS was 4.1 years, and the average time after the first seizure to CC was 7.6 years. The mean age of patients undergoing VNS implantation was 4.3 years, and the mean age for patients undergoing CC was eight. Average follow-up for all seven patients was 6.6 years. Seizures were decreased in five of the six patients with VNS and decreased in the two patients after CC. Four of the six patients who had VNS implanted had a greater than 50 % reduction in seizure frequency, and one of the six patients who had VNS implanted had a less than 50 % reduction in seizure frequency. One patient did not respond effectively to the VNS and had very limited change in seizure frequency. Both patients who had a CC had a greater than 50 % reduction in seizure frequency. CONCLUSIONS: Both VNS and CC in patients with DS can be effective at reducing seizure frequency. Patients with DS may benefit from earlier and more aggressive surgical intervention. Studies using larger patient cohorts will help clarify the role that surgery may play in the multidisciplinary approach to controlling seizures in DS. Further studies will help determine the appropriate timing of and type of surgical intervention.
Identifier
An unambiguous reference to the resource within a given context
<a href="https://doi.org/10.1007/s00381-016-3201-4">10.1007/s00381-016-3201-4</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
Bertrand ME
Childs Nervous System
Corpus Callosum/su [surgery]
Dlouhy BJ
Electroencephalography/td [trends]
Epilepsies Myoclonic/di [diagnosis]
Epilepsies Myoclonic/pp [physiopathology]
Epilepsies Myoclonic/su [surgery]
Epilepsy/di [diagnosis]
Epilepsy/pp [physiopathology]
Epilepsy/su [surgery]
Female
Humans
Infant
Jeong A
Limbrick DD Jr
Male
Miller B
November 2017 List
Palliative Care/td [trends]
Smyth MD
Vagus Nerve Stimulation
Vagus Nerve Stimulation/td [trends]