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Text
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<a href="http://doi.org/10.1111/j.1460-9592.2006.01918.x" target="_blank" rel="noreferrer">http://doi.org/10.1111/j.1460-9592.2006.01918.x</a>
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Title
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Abdominal pain related to mitochondrial neurogastrointestinal encephalomyopathy syndrome may benefit from splanchnic nerve blockade
Publisher
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Paediatric Anaesthesia
Date
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2006
Subject
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Humans; Male; Magnetic Resonance Imaging; Nerve Block; Anesthetics; adolescent; Electromyography; Neurologic Examination; Analgesics/therapeutic use; Local; Amines/therapeutic use; Cyclohexanecarboxylic Acids/therapeutic use; gamma-Aminobutyric Acid/therapeutic use; Abdominal Pain/etiology/therapy; Gastrointestinal Diseases/complications/radiography; Mitochondrial Encephalomyopathies/complications/radiography; Paresthesia/etiology; Prilocaine; Splanchnic Nerves
Creator
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Celebi N; Sahin A; Canbay O; Uzumcugil F; Aypar U
Description
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Patients diagnosed with abdominal pain related to mitochondrial neurogastrointestinal encephalopathy (MNGIE) may benefit from splanchnic nerve blockade. MNGIE, varying in age of onset and rate of progression, is caused by loss of function mutation in thymidine phosphorylase gene. Gastrointestinal dysmotility, pseudo-obstruction and demyelinating sensorimotor peripheral neuropathy (stocking-glove sensory loss, absent tendon reflexes, distal limb weakness, and wasting) are the most prominent manifestations. Patients usually die in early adulthood (mean 37.6 years; range 26-58 years). We report a case of an 18-year-old patient with MNGIE. Our patient's abdominal pain was relieved after splanchnic nerve blockade.
2006
Identifier
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<a href="http://doi.org/10.1111/j.1460-9592.2006.01918.x" target="_blank" rel="noreferrer">10.1111/j.1460-9592.2006.01918.x</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2006
Abdominal Pain/etiology/therapy
Adolescent
Amines/therapeutic use
Analgesics/therapeutic use
Anesthetics
Aypar U
Backlog
Canbay O
Celebi N
Cyclohexanecarboxylic Acids/therapeutic use
Electromyography
gamma-Aminobutyric Acid/therapeutic use
Gastrointestinal Diseases/complications/radiography
Humans
Journal Article
Local
Magnetic Resonance Imaging
Male
Mitochondrial Encephalomyopathies/complications/radiography
Nerve Block
Neurologic Examination
Paediatric Anaesthesia
Paresthesia/etiology
Prilocaine
Sahin A
Splanchnic Nerves
Uzumcugil F