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Text
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<a href="http://doi.org/10.1016/0165-1781(95)02674-6" target="_blank" rel="noreferrer">http://doi.org/10.1016/0165-1781(95)02674-6</a>
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Title
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T-lymphocyte concentrations of cholecystokinin-8 and beta-endorphin in eating disorders: II. Bulimia nervosa
Publisher
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Psychiatry Research
Date
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1995
Subject
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Female; Humans; Adult; Middle Aged; Treatment Outcome; Antidepressive Agents; Combined Modality Therapy; adolescent; Comparative Study; beta-Endorphin/blood; Cognitive Therapy; Dibenzocycloheptenes/administration & dosage; Sincalide/blood; T-Lymphocytes/drug effects/metabolism; Bulimia/blood/therapy; Fluvoxamine/administration & dosage; Serotonin Uptake Inhibitors/administration & dosage; Tricyclic/administration & dosage
Creator
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Brambilla F; Brunetta M; Draisci A; Peirone A; Perna G; Sacerdote P; Manfredi B; Panerai AE
Description
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Concentrations of cholecystokinin-8 (CCK-8) and beta-endorphin (beta-EP) in T-lymphocytes of 26 women with bulimia nervosa (BN) and in 26 age- and sex-matched healthy comparison subjects were measured. Ten patients were then treated with 300 mg/day of fluvoxamine, p.o., and five patients were treated with 300 mg/day of amineptine, p.o., for 4 months. Concentrations of the two peptides were measured again after 1, 2, and 4 months of therapy. Basal CCK-8 values were significantly lower in patients than in healthy subjects. During fluvoxamine therapy, CCK-8 values increased, reaching normal levels by month 4 of treatment. No such increase occurred during amineptine therapy. Baseline beta-EP values were normal in the bulimic patients but had declined by month 4 of fluvoxamine therapy.
1995
Identifier
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<a href="http://doi.org/10.1016/0165-1781(95)02674-6" target="_blank" rel="noreferrer">10.1016/0165-1781(95)02674-6</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
The nature or genre of the resource
Journal Article
1995
Adolescent
Adult
Antidepressive Agents
Backlog
beta-Endorphin/blood
Brambilla F
Brunetta M
Bulimia/blood/therapy
Cognitive Therapy
Combined Modality Therapy
Comparative Study
Dibenzocycloheptenes/administration & dosage
Draisci A
Female
Fluvoxamine/administration & dosage
Humans
Journal Article
Manfredi B
Middle Aged
Panerai AE
Peirone A
Perna G
Psychiatry Research
Sacerdote P
Serotonin Uptake Inhibitors/administration & dosage
Sincalide/blood
T-Lymphocytes/drug effects/metabolism
Treatment Outcome
Tricyclic/administration & dosage