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Text
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URL Address
<a href="http://doi.org/10.1111/dmcn.12519" target="_blank" rel="noreferrer">http://doi.org/10.1111/dmcn.12519</a>
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Title
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Recent trends in cerebral palsy survival. Part II: individual survival prognosis
Publisher
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Developmental Medicine And Child Neurology
Date
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2014
Subject
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adolescent; Child; Female; Humans; infant; Male; Young Adult; Adult; mortality; Prognosis; Disabled Persons; California; Cerebral Palsy; Kaplan-Meier Estimate; Preschool; Life Expectancy
Creator
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Brooks JC; Strauss DJ; Shavelle RM; Tran Linh M; Rosenbloom L; Wu YW
Description
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AIM: The aim of the study was to determine survival probabilities and life expectancies for individuals with cerebral palsy based on data collected over a 28-year period in California. METHOD: We identified all individuals with cerebral palsy, aged 4 years or older, who were clients of the California Department of Developmental Services between 1983 and 2010. Kaplan-Meier survival curves were constructed for 4-year-old children, and the estimated survival probabilities were adjusted to reflect trends in mortality by calendar year. For persons aged 15, 30, 45, and 60 years, separate Poisson regression models were used to estimate age-, sex-, and disability-specific mortality rates. These mortality rates were adjusted to reflect trends of improved survival, and life expectancies were obtained using life table methods. RESULTS: The sample comprised 16,440, 14,609, 11,735, 7023, and 2375 persons at ages 4, 15, 30, 45, and 60 years, respectively. In 1983, 50% of 4-year-old children who did not lift their heads in the prone position and were tube fed lived to age 10.9 years. By 2010, the median age at death had increased to 17.1 years. In ambulatory children the probability of survival to adulthood did not change by more than 1%. Life expectancies for adolescents and adults were lower for those with more severe limitations in motor function and feeding skills, and decreased with advancing age. Life expectancies for tube-fed adolescents and adults increased by 1 to 3 years, depending on age and pattern of disability, over the course of the study period. INTERPRETATION: Over the past three decades in California there have been significant improvements in the survival of children with very severe disabilities. There have also been improvements to the life expectancy of tube-fed adults, though to a lesser extent than in children.
2014-11
Identifier
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<a href="http://doi.org/10.1111/dmcn.12519" target="_blank" rel="noreferrer">10.1111/dmcn.12519</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2014
Adolescent
Adult
Backlog
Brooks JC
California
Cerebral Palsy
Child
Developmental Medicine and Child Neurology
Disabled Persons
Female
Humans
Infant
Journal Article
Kaplan-Meier Estimate
Life Expectancy
Male
Mortality
Preschool
Prognosis
Rosenbloom L
Shavelle RM
Strauss DJ
Tran Linh M
Wu YW
Young Adult