Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009
Humans; Terminology as Topic; Syndrome; International Agencies; Epilepsy/classification/diagnosis/etiology; Seizures/classification/diagnosis/etiology
The International League Against Epilepsy (ILAE) Commission on Classification and Terminology has revised concepts, terminology, and approaches for classifying seizures and forms of epilepsy. Generalized and focal are redefined for seizures as occurring in and rapidly engaging bilaterally distributed networks (generalized) and within networks limited to one hemisphere and either discretely localized or more widely distributed (focal). Classification of generalized seizures is simplified. No natural classification for focal seizures exists; focal seizures should be described according to their manifestations (e.g., dyscognitive, focal motor). The concepts of generalized and focal do not apply to electroclinical syndromes. Genetic, structural-metabolic, and unknown represent modified concepts to replace idiopathic, symptomatic, and cryptogenic. Not all epilepsies are recognized as electroclinical syndromes. Organization of forms of epilepsy is first by specificity: electroclinical syndromes, nonsyndromic epilepsies with structural-metabolic causes, and epilepsies of unknown cause. Further organization within these divisions can be accomplished in a flexible manner depending on purpose. Natural classes (e.g., specific underlying cause, age at onset, associated seizure type), or pragmatic groupings (e.g., epileptic encephalopathies, self-limited electroclinical syndromes) may serve as the basis for organizing knowledge about recognized forms of epilepsy and facilitate identification of new forms.
2010
Berg AT; Berkovic SF; Brodie MJ; Buchhalter J; Cross JH; van Emde BW; Engel J; French J; Glauser TA; Mathern GW; Moshe SL; Nordli D; Plouin P; Scheffer IE
Epilepsia
2010
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Journal Article
<a href="http://doi.org/10.1111/j.1528-1167.2010.02522.x" target="_blank" rel="noreferrer">10.1111/j.1528-1167.2010.02522.x</a>
New antiepileptic drugs
Humans; United States; Canada; Japan; Europe; Drug Approval; Anticonvulsants/adverse effects/contraindications/therapeutic use; Drugs; Investigational
1996
Dichter MA; Brodie MJ
The New England Journal Of Medicine
1996
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Journal Article
<a href="http://doi.org/10.1056/nejm199606133342407" target="_blank" rel="noreferrer">10.1056/nejm199606133342407</a>