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Text
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URL Address
<a href="http://doi.org/10.1007/bf02532424" target="_blank" rel="noreferrer">http://doi.org/10.1007/bf02532424</a>
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Title
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On the mathematical modelling of pain
Publisher
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Neurochemical Research
Date
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1996
Subject
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Humans; Analgesia; Reproducibility of Results; Animals; Models; Pain/physiopathology; Axons/physiology; Nerve Net/physiology; Neurological; Neuronal Plasticity; Neurons/physiology; Theoretical
Creator
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Britton NF; Skevington SM
Description
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In this review a case is presented for the use of mathematical modelling in the study of pain. The philosophy of mathematical modelling is outlined and a recommendation is made for the use of modern nonlinear techniques and computational neuroscience in the modelling of pain. Classic and more recent examples of modelling in neurobiology in general and pain in particular, at three different levels-molecular, cellular and neural networks-are described and evaluated. Directions for further progress are indicated, particularly in plasticity and in modelling brain mechanisms. Major advantages of mathematical modelling are that it can handle extremely complex theories and it is non-invasive, and so is particularly valuable in the investigation of chronic pain.
1996
Identifier
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<a href="http://doi.org/10.1007/bf02532424" target="_blank" rel="noreferrer">10.1007/bf02532424</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
1996
Analgesia
Animals
Axons/physiology
Backlog
Britton NF
Humans
Journal Article
Models
Nerve Net/physiology
Neurochemical Research
Neurological
Neuronal Plasticity
Neurons/physiology
Pain/physiopathology
Reproducibility of Results
Skevington SM
Theoretical